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Regional Changes in Metabolism in Hypoxia-Ischemia

  • F. A. Welsh
  • M. J. O’Connor
  • W. Rieder
  • V. R. Marcy
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 78)

Abstract

The purpose of this study is to describe regional metabolic changes following an episode of cerebral ischemia in the cat. Regional characterization of metabolic derangements is imperative because it is unlikely that cerebral blood flow is uniformly reduced in most hypoxic-ischemic episodes.1, 2, 3 Furthermore, neurons in discrete anatomic regions such as hippocampus or arterial border zones4 are selectively vulnerable to hypoxia-ischemia. Consequently, we have investigated regional alterations of cerebral metabolites in a model of incomplete ischemia (oligemia).

Keywords

White Matter Gray Matter Metabolite Level Cortical Surface Subcortical White Matter 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • F. A. Welsh
    • 1
  • M. J. O’Connor
    • 1
  • W. Rieder
    • 1
  • V. R. Marcy
    • 1
  1. 1.Division of NeurosurgeryUniv. of Penna.PhiladelphiaUSA

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