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Catecholamines and 3′,5′ Cyclic AMP in Carotid Body Chemoreception in the Cat

  • Robert S. Fitzgerald
  • Ellen M. Rogus
  • Abbas Dehghani
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 78)

Abstract

Almost fifty years have passed since the discovery of the carotid body. Its proper functioning seems essential to the organism’s normal respiratory (1), circulatory (2), endocrine (3) responses to hypoxia. It is common knowledge that the carotid body normally responds to changes in carbon dioxide and hydrogen ion as well. But exactly which structure or structures in the carotid body act as the receptor for these stimuli, and what processes or mechanisms are operating to transduce changes in oxygen, carbon dioxide, and hydrogen ion into changes in neural output are not known.

Keywords

Adenylate Cyclase Carotid Body Microsomal Fraction Adenylate Cyclase Activity Superior Cervical Ganglion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Robert S. Fitzgerald
    • 1
  • Ellen M. Rogus
    • 1
  • Abbas Dehghani
    • 1
  1. 1.The Department of Environmental Medicine and The Department of PhysiologyThe Johns Hopkins UniversityBaltimoreUSA

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