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Some Aspects of Localization, Depletion, Uptake and Turnover of Catecholamines by Glomus Cells of the Rat Carotid Body

  • Arthur Hess
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 78)

Abstract

The carotid body has been shown biochemically to contain catecholamines, predominantly dopamine1. Further evidence for the presence of catecholamines in glomus cells is provided by studies of histofluorescence, and glomus cells fluoresce intently after exposure to hot paraformaldehyde vapor,2 3, 4, a histochemical test specific for catecholamines5. The glomus cells of the rat carotid body contain numerous dense-core or granulated vesicles6, 7, resembling somewhat the vesicles seen in other catecholaminergic cells and nerve fibers. Presumably these vesicles are the site of location, wholly or in part, of the neurotransmitter substances. The biochemical tests show that the catecholamines are in the carotid body, and the histofluorescence studies demonstrate that the catecholamines are in the glomus cells. However, definitive proof has still not yet been presented that the dense-core vesicles are indeed the site of storage of catecholamines in glomus cells.

Keywords

Osmium Tetroxide Carotid Body Dense Core Sympathetic Ganglion Superior Cervical Ganglion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Arthur Hess
    • 1
  1. 1.Department of AnatomyRutgers Medical School-CMDNJPiscatawayUSA

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