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Intracellular Studies of Carotid Body Cells: Effects of Temperature, “Natural” Stimuli and Chemical Substances

  • C. Eyzaguirre
  • Margarita Baron
  • R. Gallego
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 78)

Abstract

The carotid body consists of clusters of small cells which have received several names such as epithelioid, glomus, chemoreceptor, etc., in addition to a network of nerve fibers and capillaries. The glomus cells, more recently, have been designated as type I and are surrounded by another type of cell which has been designated as sustentacular, capsular, satellite or type II.

Keywords

Nerve Ending Carotid Body Input Resistance Bathing Medium Glomus Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Hess, A., Zapata, P. Innervation of the cat carotid body: normal and experimental studies. Fedn. Proc. 31:1365–1382, 1972.Google Scholar
  2. 2.
    Fidone, S.J., Stensaas, L.J., Zapata, P. Sensory nerve endings containing “synaptic” vesciles: an electron microscope autoradiographic study. J. Neurobiol. 6:423–427, 1975.PubMedCrossRefGoogle Scholar
  3. 3.
    Castro, de F. Sur la structure de la synapse dans les chemo-cepteurs: leur mécanisme d’excitation et rôle dans la circulation sanguine locale. Acta physiol. Scand., 22:14–43, 1951.CrossRefGoogle Scholar
  4. 4.
    Eyzaguirre, C, Nishi, K. Further study on mass receptor potential of carotid body chemosensors. J. Neurophysiol., 37: 156–169.Google Scholar
  5. 5.
    Eyzaguirre, C, Nishi, K. Effects of different ions on resting polarization and on the mass receptor potential of carotid body chemosensors. J, Neurobiol.,1976 (in press).Google Scholar
  6. 6.
    Baron, M., Eyzaguirre, C. Thermal responses of carotid body cells. J. Neurobiol., 6:521–527, 1975.PubMedCrossRefGoogle Scholar
  7. 7.
    Hubbard, J.I., Llinás, R., Ouastel, D.M.J, Electrophysiological analysis of synaptic transmission. Baltimore, The Williams & Wilkins Co., 1969.Google Scholar
  8. 8.
    Shanes, A.M. Electrochemical aspects of physiological and pharmacological action in excitable cells. Pharmacol. Rev., 10:59–273, 1958.PubMedGoogle Scholar
  9. 9.
    Brown, A.M. Effects of CO2 and pH on neuronal membranes. Fedn. Proc, 31:1399–1403, 1972.Google Scholar
  10. 10.
    Goodman, N.W., McCloskey, D.I. Intracellular potentials in the carotid body. Brain Res., 39:501–504, 1972.PubMedCrossRefGoogle Scholar
  11. 11.
    Eyzaguirre, C, Fidone, S., Nishi, K. Recent studies on the generation of chemoreceptor impulses. In Purves, M.J. (Editor): The Peripheral Arterial Chemoreceptors. Cambridge University Press, 1975, pp. 175–194.Google Scholar
  12. 12.
    Daly, M. de B., Lambertsen, C.J., Schweitzer, A. Observations on the volume of blood flow and oxygen utilization of the carotid body in the cat. J. Physiol., 125:67–89, 1954.Google Scholar
  13. 13.
    Gallego, R., Eyzaguirre, C. Effects of osmotic pressure changes on the carotid body of the cat in vitro. Fedn. Proc., 35:404, 1976.Google Scholar
  14. 14.
    Hubbard, J.I., Jones, S.F., Landau, E.M. An examination of the effects of osmotic pressure changes upon transmitter release from mammalian motor nerve terminals. J. Physiol., 197:639–657, 1968.PubMedGoogle Scholar
  15. 15.
    Eyzaguirre, C., Zapata, P. The release of acetylcholine from carotid body tissues. Further study on the effects of acetylcholine and cholinergic blocking agents on the chemosensory discharge. J. Physiol., 195:589–607, 1968.PubMedGoogle Scholar
  16. 16.
    Torrance, R.W. Arterial chemoreceptors. In Widdicombe, J.G. (Editor): Respiratory Physiology, MTP International Review of Science, London: Butterworths, 1974, pp. 247–271.Google Scholar
  17. 17.
    Verna, A., Roumy, M., Leitner, L.-M. Loss of chemoreceptive properties of the rabbit carotid body after destruction of the glomus cells. Brain Res., 100:13–23, 1976,CrossRefGoogle Scholar
  18. 18.
    Zapata, P., Stensaas, L.J., Eyzaguirre, C. Axon regeneration following a lesion of the carotid nerve: electrophysiological and ultrastructural observations. Brain Res., 1976 (in press).Google Scholar
  19. 19.
    Paintal, A.S. Mechanism of stimulation of aortic chemoreceptors by natural stimuli and chemical substances. J. Physiol., 189: 63–84, 1967.PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • C. Eyzaguirre
    • 1
  • Margarita Baron
    • 1
  • R. Gallego
    • 1
  1. 1.Dept. of PhysiologyUniv. of Utah College of MedicineSalt Lake CityUSA

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