Abstract
In both hemorrhagic and endotoxic shock, a diminished venous return is probably responsible for the decreased cardiac output. Although the heart eventually fails in both types of shock, it is unclear whether cardiac failure is responsible for the irreversibility of the condition. Also, it is unknown whether alterations of myocardial metabolism precede cardiac failure and, if so, whether they are due to or simply a reflection of myocardial hypoxia.
Supported by the U.S. Navy Themis Project and by Grants HE03130 and HE04916 from the National Heart Institute.
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© 1972 Plenum Press, New York
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Spitzer, J.J., Spitzer, J.A., Weng, J.T., Scott, J.C. (1972). Myocardial Metabolism During Acute Hemorrhagic or Endotoxic Shock. In: Hinshaw, L.B., Cox, B.G. (eds) The Fundamental Mechanisms of Shock. Advances in Experimental Medicine and Biology, vol 23. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9014-9_25
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DOI: https://doi.org/10.1007/978-1-4615-9014-9_25
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