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Fine Structure of Testicular Interstitial Cells in Humans

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The Human Testis

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 10))

Abstract

It is now well established that the interstitial or Leydig cells are the principal site of androgen production in the mammalian testis. In rats, the interstitial tissue can be separated from the seminiferous tubules and shows considerably more activity than the tubules in synthesizing androgen from cholesterol in vitro (1, 2). Proof that the interstitial cells are indeed the source of this activity within the interstitial tissue comes from histochemical studies in which the reaction product of 3ß -hydroxysteroid dehydrogenase appears mainly in these cells. This approach has been applied to a variety of vertebrate species with consistent results, although it appears somewhat more difficult to demonstrate in the human testis (3).

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Author information

Authors and Affiliations

  1. Department of Anatomy, Stanford School of Medicine, Stanford, California, 94305, UK

    A. Kent Christensen

Authors
  1. A. Kent Christensen
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Editor information

Editors and Affiliations

  1. Medical Research Institute of Worcester, Inc., Worcester City Hospital, Worcester, Massachusetts, USA

    Eugenia Rosemberg M. D. (Research Director) (Research Director)

  2. University of Washington School of Medicine, Seattle, Washington, USA

    C. Alvin Paulsen M. D. (Professor of Medicine) (Professor of Medicine)

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© 1970 Plenum Press, New York

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Christensen, A.K. (1970). Fine Structure of Testicular Interstitial Cells in Humans. In: Rosemberg, E., Paulsen, C.A. (eds) The Human Testis. Advances in Experimental Medicine and Biology, vol 10. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9008-8_8

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  • DOI: https://doi.org/10.1007/978-1-4615-9008-8_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9010-1

  • Online ISBN: 978-1-4615-9008-8

  • eBook Packages: Springer Book Archive

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