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The Neurobiology of the Amygdala pp 793–813Cite as

Effects of Amygdaloid Lesions on Hypothalamic Macromolecules

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Part of the book series: Advances in Behavioral Biology ((ABBI,volume 2))

Abstract

The role of the amygdaloid nuclear complex in endocrinology did not become apparent until the late 1950s when a number of detailed studies investigated the relationship of electrical stimulation and electrolytic lesions of the amygdala on sexual behavior, fear, and arousal. As a result of these studies, it was found that electrical stimulation of the amygdala in female rats, rabbits, cats, and dogs produces ovulation and increased uterine contractility (Bunn and Everett, 1957; Koikegami, Yamada, and Usui, 1953; Shealy and Peele, 1957). The major psychoendocrine effect of lesions in the amygdala is the disruption of maternal behavior (Masserman et al., 1958; Walker, Thompson and McQueen, 1953). One of the unexplained phenomena has been the differential effects of amygdalectomy in the two sexes. Paradoxically, although amygdaloid lesions cause more hypersexuality in males than in females, the effects on the genital organ show the opposite picture. Amygdalectomy in adult male rats and cats causes a significant degeneration of the testes, whereas in adult female cats the ovaries remain unaffected (Greer and Yamada, 1959; Kling et al., 1960; Yamada and Greer, 1960), and in the young female cat, amygdalectomy causes a precocious development of the ovaries, uterus, and vagina (Elwers and Critchlow, 1961; Lundberg, 1962).

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Authors and Affiliations

  1. The Jackson Laboratory, Bar Harbor, Maine, USA

    Basil E. Eleftheriou

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  1. Basil E. Eleftheriou
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© 1972 Plenum Press, New York

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Eleftheriou, B.E. (1972). Effects of Amygdaloid Lesions on Hypothalamic Macromolecules. In: The Neurobiology of the Amygdala. Advances in Behavioral Biology, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-8987-7_32

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  • DOI: https://doi.org/10.1007/978-1-4615-8987-7_32

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-8989-1

  • Online ISBN: 978-1-4615-8987-7

  • eBook Packages: Springer Book Archive

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