Skip to main content

Human Population Monitoring

  • Chapter
Chemical Mutagens

Abstract

Monitoring the human population is not the preferred way of detecting and identifying environmental mutagens. It is far better that they be discovered in advance, before they come into use. The methods discussed elsewhere in this book are intended for screening potentially dangerous chemicals and removing or restricting those that are found to be mutagenic. The belated discovery of an increased human mutation rate tells us that the screening system has failed. The damage is already done, and will be felt by our descendants for many generations in the future.

Paper No. 1362 from the Genetics Laboratory, University of Wisconsin, Madison, Wisconsin.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. J. F. Crow, Chemical risk to future generations, Scientist and Citizen 10, 113–117 (1968).

    Article  Google Scholar 

  2. J. V. Neel and A. D. Bloom, The detection of environmental mutagens, Med. Clin. N. Amer. 53, 1243–1256 (1969).

    PubMed  CAS  Google Scholar 

  3. H. J. Sanders, Chemical mutagens, Chem. Eng. News 47, 51–71, 54–68 (May 19, June 2, 1969).

    Google Scholar 

  4. H. J. Muller, Our load of mutations, Am. J. Human Genet. 2, 111–176 (1950).

    CAS  Google Scholar 

  5. S. Wright, On the appraisal of genetic effects of radiation in man, in “Biological Effect of Atomic Radiation” pp. 18–24, N.A.S.-NRC (1960).

    Google Scholar 

  6. M. W. Shaw, Human chromosome damage by chemical agents, Ann. Rev. Med. 21, 409–432 (1970).

    Article  PubMed  CAS  Google Scholar 

  7. N. Wald and J. G. Castle, Computer methods in the study of human chromosomes, in “Symposium on Human Cytogenetics,” pp. 49–64, University of Tennessee (1969).

    Google Scholar 

  8. V. A. McKusick, “Mendelian Inheritance in Man,” Johns Hopkins Press, Baltimore (1968).

    Google Scholar 

  9. T. Mukai, The genetic structure of natural populations of Drosophila melanogaster. I. Spontaneous mutation rate of polygenes controlling viability, Genetics 50, 1–19 (1964).

    PubMed  CAS  Google Scholar 

  10. H. J. Whitfield, R. G. Martin, and B. N. Ames, Classification of mutants in the C gene of the histidine operon, J. Mol. Biol. 21, 335–355 (1966).

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1971 Plenum Press, New York

About this chapter

Cite this chapter

Crow, J.F. (1971). Human Population Monitoring. In: Hollaender, A. (eds) Chemical Mutagens. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-8969-3_13

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-8969-3_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-8971-6

  • Online ISBN: 978-1-4615-8969-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics