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Polymers of β-Lactam Antibiotics: Structural, Chemical and Biological Properties

  • M. K. Stanfield
  • B. L. Warren
  • F. H. Wilson

Abstract

Polymers of benzylpenicillin, ampicillin and cephaloridine have been isolated, physically examined and tested for allergenicity. Five of eleven penicillin sensitive subjects were found to give a positive response in the lymphocyte transformation test (LTT) while two tested individuals showed release of histamine from basophils. Two penicillin sensitive subjects also gave positive LTT with cephaloridine polymer.

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Copyright information

© Springer Science+Business Media New York 1978

Authors and Affiliations

  • M. K. Stanfield
    • 1
  • B. L. Warren
    • 1
  • F. H. Wilson
    • 1
  1. 1.Department of BiochemistryTulane Medical SchoolNew OrleansUSA

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