Lateral Species Separation in the Lipid Bilayer

  • P. H. Von Dreele


The different lipid species in a system of two different kinds of lipids arranged in a bilayer can be well mixed with little lateral species separation or poorly mixed with a large degree of excess lateral species separation according to the magnitude of the nonideal intermolecular forces between the two kinds of lipids in the surface. I shall begin this talk by defining the terms we will be using to describe the excess lateral species separation; secondly, comment on the experimental measurements required to determine the degree of excess species separation; thirdly, discuss the theory for two dimensional systems which we have developed to analyze the data; and finally talk about the ways to represent the results which will give a good physical picture of the membrane.


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  1. 1.
    Von Dreele, P. H., Poland, D., and Scheraga, H. A. (1971) Macromolecules 4, 396CrossRefGoogle Scholar
  2. 2.
    Shimshick, E. J. and McConnell, H. M. (1973) Biochemistry 12, 2351CrossRefGoogle Scholar
  3. 3.
    Von Dreele, P. H. Biochemistry, in press.Google Scholar
  4. 4.
    Von Dreele, P. H. Biochem. Biophys. Res. Commun., in press.Google Scholar

Copyright information

© Springer Science+Business Media New York 1978

Authors and Affiliations

  • P. H. Von Dreele
    • 1
  1. 1.Northwestern UniversityEvanstonUSA

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