Immunization Against Erythrocytic Forms of Malaria Parasites

  • S. Cohen
  • G. A. Butcher
  • G. H. Mitchell
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 93)


It is almost 20 years since a worldwide program of malaria eradication was formally adopted by the 8th World Health Assembly and its implementation coordinated by the World Health Organization (WHO). The strategy of eradication involved widespread indoor spraying with residual insecticides and elimination of remaining foci using antimalarial drugs and further spraying. The success of this international endeavor can be judged from a recent WHO report showing that malaria has been eradicated or controlled in almost 80% of originally malarious zones.* However, the remaining areas where eradication could not be implemented include 66 countries covering vast tracts of the developing world, notably in Africa, inhabited by about 500 million people. Reliable data are not available from these areas, but it seems likely that malaria at present produces a morbidity rate of 100 million and mortality of about 1 million per annum, mainly among young children. Moreover, the resurgence of malaria in Pakistan, Bangladesh, Sri Lanka, and several Indian provinces that all had advanced eradication programs is a source of much alarm. It is clear that tropical areas still harbor a vast reservoir of malarial infection and that its eradication or even containment is no longer feasible with available health facilities.


Rhesus Monkey Antigenic Variation Blood Parasite Malarial Infection Rodent Malaria 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • S. Cohen
    • 1
  • G. A. Butcher
    • 1
  • G. H. Mitchell
    • 1
  1. 1.Department of Chemical PathologyGuy’s Hospital Medical SchoolLondonUK

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