Antigenic Variation in Babesia

  • John J. Doyle
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 93)


As babesiosis has been the subject of several recent reviews (Mahoney 1972; Riek 1968; Ristic 1970) and is the subject of another chapter in this volume (Callow, Chapter 8), I will only briefly present the evidence now available to show that antigenic variation also occurs in this disease. Parasites of the genus Babesia, intraerythrocytic parasites in the mammalian host, are transmitted by ixodid ticks. They represent a widespread problem in domestic animal husbandry, causing a disease characterized by erythrocyte destruction with anemia, jaundice, and hemoglobinemia. The patterns of morbidity and mortality depend on the conditions under which the animals are maintained.


Antigenic Variation Blood Parasite Ixodid Tick Salivary Gland Cell Erythrocyte Agglutination 
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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • John J. Doyle
    • 1
  1. 1.Research and Training CenterWorld Health Organization ImmunologyLausanneSwitzerland

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