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Immunoprophylaxis Against Chagas’ Disease

  • Antonio R. L. Teixeira
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 93)

Abstract

Chagas’ disease is caused by Trypanosoma cruzi, a flagellate protozoan transmitted by an hematophagus reduviid bug. This disease, identified by Dr. Carlos Chagas in 1909 (Chagas 1909, 1910), is a major public health problem in rural areas of Central and South America. Approximately 35 million people are estimated to be at risk of Trypanosoma cruzi infection, and at least 7 million have already been infected (Pan American Health Organization 1970). Human cases have been described from the southern United States to southern Argentina (Marsden 1971). Where Chagas’ disease is endemic, chronic myocarditis is the leading cause of sudden death and heart failure (Laranja et al. 1956). Certain digestive disturbances are also common manifestations of chronic Chagas’ disease (Vampré 1923; Prado 1945; Köberle & Nador 1955).

Keywords

Immune Protection Humoral Antibody Trypanosoma Cruzi Culture Form Blood Parasite 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Antonio R. L. Teixeira
    • 1
  1. 1.Faculdade de Ciencias da SuadeUniversidade de BrasiliaBrasiliaBrazil

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