Skip to main content

Iron and Copper Metabolism in Cancer, as Exemplified by Changes in Ferritin and Ceruloplasmin in Rats with Transplantable Tumors

  • Chapter
Morris Hepatomas

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 92))

Abstract

Iron and copper are crucial to the metabolism of all eukaryotic cells and are often linked in their functions (17). Both elements are associated with electron transport and in mammals are required for the formation of hemoglobin in erythropoisis. Iron and copper are stored in the liver of the fetus during the first part of gestation for utilization during the first part of life when the diet (milk) contains little of these elements.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Aisen, P. and Brown, E.B. (eds). Proteins of Iron Metabolism, Grune and Stratton, New York (1977).

    Google Scholar 

  2. Cohen, D.I. and Linder, M.C. Cooper Absorption in Tumor Bearing Rats. Manuscript in preparation.

    Google Scholar 

  3. Drysdale, J.W. and Munro, H.N. J. Biol. Chem. 241 (1966) 3630.

    PubMed  CAS  Google Scholar 

  4. Evans, G.W. Physiol. Rev. 53 (1973) 535.

    PubMed  CAS  Google Scholar 

  5. Hevesy, G. and Lockner, D. Arkiv. Kemi. 19 (1961) 303.

    Google Scholar 

  6. Hsieh, H.S. and Frieden, E. Bioch. Biophys. Res. Comm. 67 (1975) 1326.

    Article  CAS  Google Scholar 

  7. Knox, W.E., Linder, M.C. and Friedell, G.H. Cancer Res. 30 (1970) 283.

    PubMed  CAS  Google Scholar 

  8. Knox, W.E., Linder-Horowitz, M. and Friedell, G.H. Cancer Res. 29 (1969) 669.

    PubMed  CAS  Google Scholar 

  9. Linder, M.C., Bryant, R.R., Lim, S,, Scott, L.E., and Moor, J.R. Ceruloplasmin Elevation and Synthesis in Rats with Trasnplantable Tumors. Submitted for publication.

    Google Scholar 

  10. Linder, M.C., Houle, P.A., Isaacs, E., Moor, J.R. and Scott, L.E. Regulation of Ceruloplasmin by Copper in Normal and Copper-Deficient Rats. Submitted for publication.

    Google Scholar 

  11. Linder, M.C. and Moor, J.R. Plasma Ceruloplasmin and Copper in Pulmonary Cancer. In: Proceedings of the Third International Conference on Detection and Prevention of Cancer, New York, in press, (1977).

    Google Scholar 

  12. Linder, M.C. and Moor, J.R. Plasma Ceruloplasmin: Evidence for its Presence in and U take by Heart and Other Organs of the Rat. Bioch. Biophys. Acta, in press (1977).

    Google Scholar 

  13. Linder, M.C., Moor, J.R., Munro, H.N. and Morris, H.P. Biochem. Biophys. Acta 386 (1975) 409.

    Article  PubMed  CAS  Google Scholar 

  14. Linder, M.C., Moor, J.R., Munro, H.N. and Morris, H.P. In: Gann Monograph for Cancer Res. S. Weinhouse and T. Ono (eds). 13 (1972) 299.

    Google Scholar 

  15. Linder, M.C., Moor, J.R., Scott, L.E. and Munro, H.N. Biochem. Biophys. Acta 297 (1973) 70.

    Article  PubMed  CAS  Google Scholar 

  16. Linder, M.C. and Munro, H.N. Analyt. Bioch. 48 (1972) 266.

    Article  CAS  Google Scholar 

  17. Linder, M.C. and Munro, H.N. Enzyme 15 (1974) 111.

    Google Scholar 

  18. Linder, M.C. and Munro, H.N. Mechanism of Iron Absorption. Fed. Proc., in press, (1977).

    Google Scholar 

  19. Linder, M.C., Munro, H.N. and Morris, H.P. Cancer Res. 30 (1970) 2231.

    PubMed  CAS  Google Scholar 

  20. Linder, M.C., Zahringer, J., Baliga, B.S., Drake, R.L., Barres, B., and Munro, H.N. In: Proteins of Iron Metabolism. P. Aisen and E.B. Brown (eds). Grune and Stratton, New York, in press (1977).

    Google Scholar 

  21. Morris, H.P., Wagner, B.P. and Meranze, D.R. Cancer Res. 30 (1970) 1362.

    PubMed  CAS  Google Scholar 

  22. Osaki, S. and Johnson, D.A. J. Biol. Chem. 244 (1969) 5757.

    PubMed  CAS  Google Scholar 

  23. Petering, H.G, and Vangiessen, G.J. In: The Biochemsitry of Copper. J. Peisach, P. Aisen and W.E. Blumberg (eds). Academic Press, New York (1966) p. 197.

    Google Scholar 

  24. Ragan, H.A., Nacht, S., Lee, G.R., Bishop, C.R. and Cartwright, G.E. Am. J. Physiol. 217 (1969) 1320.

    PubMed  CAS  Google Scholar 

  25. Richter, G.W. Nature 207 (1965) 616.

    Article  PubMed  CAS  Google Scholar 

  26. Robbins, E. and Pederson, T. Proc. Natl. Acad. Sci. U.S.A 66 (1970) 1244.

    Article  PubMed  CAS  Google Scholar 

  27. Takamiya, K. Nature 185 (1960) 190.

    Article  PubMed  CAS  Google Scholar 

  28. Vulimiri, L., Catsimpoolas, N., Griffith, A., Linder, M.C. and Munro, H.N. Biochem. Biophys. Acta 412 (1975) 148.

    Article  PubMed  CAS  Google Scholar 

  29. Vanngard, T. In: Biological Spplications of ESR. H.M. Swartz, J.R. Bolton, and T. Borg (eds), Wiley-Interscience, New York, (1972) p. 411.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1978 Plenum Press, New York

About this chapter

Cite this chapter

Linder, M.C. (1978). Iron and Copper Metabolism in Cancer, as Exemplified by Changes in Ferritin and Ceruloplasmin in Rats with Transplantable Tumors. In: Morris, H.P., Criss, W.E. (eds) Morris Hepatomas. Advances in Experimental Medicine and Biology, vol 92. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-8852-8_25

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-8852-8_25

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-8854-2

  • Online ISBN: 978-1-4615-8852-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics