Abstract
The variety of Morris hepatomas with their properties ranging from minimal deviation, slow growing tumors to undifferentiated, fast replicating carcinomas have been invaluable in their contribution to the understanding of basic mechanisms in cellular biology and biochemistry. The ability to culture (Fig 1) and clone many of these tumors have enhanced their value since under conditions in vitro genetically homogeneous populations, derived from single cells, could be readily studied.
This investigation was supported in part by Grant Number CA 12536 awarded by the National Cancer Institute, DHEW.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Borek, C. Proc. Nat. Acad. Sci. U.S.A. 69 (1972) 956.
Borek, C. In: Gene Expression and Carcinogenesis in Cultured Liver, L.E. Gerschenson and E.B. Thompson (eds). Academic Press, New York (1975) 62.
Borek, C., Grob, M. and Burger, M.M. Exp. Cell Res. 77 (1973) 207.
Borek, C., Higashino, S. and Lowenstein, W.R. J. Mem. Biol. 1 (1969) 274.
Borek, C. and Pain, C. Proc. Am. Assoc. Cancer Res. 18 (1977) 193.
Brady, R.O., Borek, C. and Bradley, R.M. J. Biol. Chem. 244 (1969) 6552.
Burger, M.M. Proc. Nat. Acad. Sci. U.S.A. 62 (1969) 994.
Fishman, P.H., Brady, R.O., Bradley, R.M., Aaronson, S.A. and Todaro, G.J. Proc. Nat. Acad. Sci. U.S.A. 71 (1974) 298.
Freund, J.S., Dempsey, E.W., Loeb, J.N. and Borek, C. Proc. of the Soc. for Exp. Biol, and Med. 150 (1975) 14.
Loeb, J.N., Borek, C. and Yeung, L.L. Proc. Nat. Acad. Sci. U.S.A. 70 (1973) 3852.
Miller, D.A., Dev, V.G., Borek, C. and Miller, O.J. Cancer Res. 32 (1972) 2375.
Morris, H.P., Sydransky, H., Wagner, B.P. and Dyer, H.H. Cancer Res. 20 (1960) 1252.
Pitot, H.C., Periano, C., Morse, P.S. and Potter, V.R. Nat. Cancer Inst. Monog. 13 (1964) 229.
Poste, G. Cancer Res. 35 (1976) 2558.
Richardson, V.I., Tashjian, A.H. Jr. and Levine, L. J. Cell Biol. 40 (1969) 236.
Smith, J.E., Muto, Y., Milch, P.O., Goodman, D.W. J. Biol. Chem. 248 (1973) 1544.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1978 Plenum Press, New York
About this chapter
Cite this chapter
Borek, C. (1978). Surface Membranes and Biological Regulation in Differentiated Hepatoma Cells In Vitro . In: Morris, H.P., Criss, W.E. (eds) Morris Hepatomas. Advances in Experimental Medicine and Biology, vol 92. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-8852-8_18
Download citation
DOI: https://doi.org/10.1007/978-1-4615-8852-8_18
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4615-8854-2
Online ISBN: 978-1-4615-8852-8
eBook Packages: Springer Book Archive