Abstract
The differentiation of striated muscle from embryonic myoblasts in cell culture reproduces the processes by which the structural and functional characteristics of differentiated muscle fibers are formed in the organism with remarkable fidelity. The one notable difference is the unusual degree of synchrony which can be achieved in cell culture.
The original researches of the author, discussed in this paper, were supported by grants from the National Science Foundation (GB-5963X), the National Institutes of Health, U.S.P.H.S. (HD 07083) and a grant-in-aid from the Muscular Dystrophy Association of America.
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Konigsberg, I.R. (1977). The Culture Environment and Its Control of Myogenesis. In: Nichols, W.W., Murphy, D.G. (eds) Regulation of Cell Proliferation and Differentiation. Cellular Senescence and Somatic Cell Genetics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-8846-7_5
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DOI: https://doi.org/10.1007/978-1-4615-8846-7_5
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