Abstract
Increases in specific activities of several different lysosomal enzymes in muscle disease states have implicated the lysosome in muscle atrophy (12). However, lysosomal degradation of myofibrillar proteins has not been demonstrated. We have re-evaluated the lysosome and other degradative systems in denervation atrophy in order to better understand this important problem.
W.T. Stauber is a MDAA Postdoctoral Fellow. This work was supported in part by USPHS grant NINDS 08550, and a grant from MDAA, Inc.
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© 1977 J. Stefan Institute, Ljubljana, Yugoslavia
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Stauber, W.T., Hedge, A.M., Schottelius, B.A. (1977). On the Lysosomal Role in Skeletal Muscle Catabolism Following Denervation. In: Turk, V., Marks, N., Barrett, A.J., Woessner, J.F. (eds) Intracellular Protein Catabolism II. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-8813-9_23
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DOI: https://doi.org/10.1007/978-1-4615-8813-9_23
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