Abstract
Quantitative appraisals of genetically determined diseases such as the gangliosidoses are only accurate to the degree to which the affected populations under study are genotypically homogeneous. It is certainly apparent that any genetic survey which includes the inadvertent pooling of phenotypically similar, but genetically different, disorders can lead to misleading conclusions.
Dedicated to the memory of Dr. Melissa L. Richter.
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Aronson, S.M. (1975). Epidemiology. In: Volk, B.W., Schneck, L. (eds) The Gangliosidoses. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-8726-2_5
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