Skip to main content
SpringerLink
Log in

Prediction and Measurement of Perceptual-Behavioral Change in Drug-Induced Hallucinations

  • Chapter
Origin and Mechanisms of Hallucinations

Abstract

Hallucinations can be defined as intense sensations with simultaneously inhibited or even blocked intention and ability to verify those sensations through voluntary motor performance. Such a view can accommodate even Delay and Pichot’s [1] phantom sensations defined as kinesthetic hallucinations; indeed, phantom phenomena can impressively illustrate the meaning of our new definition of hallucinations since concomitant with the intensely active (phantom) sensation of a limb, the absence of the latter represents a complete “blocking” of motor manifestations. Further, Prevosnik and Eckenhoff [2] produced phantom sensation during spinal anesthesia by keeping the lower extremity flexed until the induction of motor paralysis. A proprioceptive phantom was produced, i.e. patients felt the extremity to be in the position prior to induction of motor blockade in spite of the fact that the limbs were returned to resting position after the induction of motor paralysis. The phantom persisted throughout motor blockade despite the loss of the sense of position.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

a

  1. J. Delay and P. Pichot, “Abrégé de Psychologie”, 2e edition. Paris. Masson & Cie., Editeurs, 1964

    Google Scholar 

  2. S.J. Prevosnik and J.S. Eckenhoff, “Phantom sensations during spinal anesthesia”. Anesthesiology 25:767, 1964

    Article  Google Scholar 

  3. J.P. Zubek, M. Aftanas, K. Kobach, L. Wilgosh and G. Winocur, “Effect of severe immobilization of the body on intellectual and perceptual processes”, Canad.J.Psychol. 17:l8, 1963

    Article  Google Scholar 

  4. D.E. Graveline, B. Blake, R.E. McKenzie and B. Harmon, “Psychobiologic effects of vater-immersion-induced hypodynamics”. Aerospace Med. 32:387, 1961

    PubMed  Google Scholar 

  5. I. Courtney, J.M. Davis and P. Solomon, “Sensory deprivation; the role of movement”, Percept.Motpr Skills, 13:191, 1961

    Article  Google Scholar 

  6. K. Boman, “Psychological testing before and after a period of isolation”, Acta Psychiat.Scand.Suppl. l80:463, 1964

    Article  Google Scholar 

  7. J.P. Zubek and L. Wilgosh, “Prolonged immobilization of the body; changes in performance and in the electroencephalogram” Science 140:306, 1963

    Article  PubMed  Google Scholar 

  8. D.W. Fiske, In: Functions of Varied Experiences, D.W. Fiske and S.R. Maddi, eds., Homewood, Illinois, Dorsey Press, 1961

    Google Scholar 

  9. S.I. Cohen, A.J. Silverman, B. Bressler and B. Shanavonian, “Problems in isolation studies”, In: Sensory Deprivation, P. Solomon et al., eds., Cambridge, Harvard University Press, 1961

    Google Scholar 

  10. S.J. Freedman, H.V. Greenebaum and M. Greenblatt, “Perceptual and cognitive changes in sensory deprivation”, In: Sensory Deprivation. P. Solomon et al., eds., Cambridge, Harvard Univ. Press, 1961

    Google Scholar 

  11. T. Schaefer and N. Bernick, “Sensory deprivation and its effects on perception”, In: Psychopathology of Perception. P.H. Hoch and J. Zubin, eds. New York, Grune and Stratton, 1965

    Google Scholar 

  12. H. Leiderman, J.H. Mendelson, D. Wexler and P. Solomon, “Sensory deprivation: Clinical aspects” A.M.A. Arch.Intern. Med. 101:389, 1958

    Article  Google Scholar 

  13. J. Mendelson, P. Solomon and E. Lindemann, “Hallucinations of poliomyelitis patients during treatment in a respirator” J.Nerv.Ment.Dis. 126:421, 1958

    Article  PubMed  Google Scholar 

  14. G.W. Williams, “Hypnosis in perspective”, In: Experimental Hypnosis, L.M. LeCron, ed., New York, Macmillan, 1958

    Google Scholar 

  15. G. Erickson and G. Gustafson, “Controlling auditory hallucination” Hosp.Community Psychiat. 19:327, 1968

    Google Scholar 

  16. R. Fischer, “The biological fabric of time, in interdisciplinary perspectives of time”, Ed. R. Fischer, Ann.N.Y. Acad.Sci. 138:369, 1967

    Google Scholar 

  17. E.W. Straus, “Phenomenology of hallucinations”,In: Hallucinations, L.J. West, ed., New York, Grune and Stratton, 1962

    Google Scholar 

  18. H. Schulz, A. Meyer and R. Cohen, “Experimenteller Traiim-Entzug und psychische Veränderungen”, Nervenarzt 39:193, 1968

    PubMed  Google Scholar 

  19. J. Wyrsch, “Die Person des Schizophrenen”, Bern, Haupt, 1949

    Google Scholar 

  20. R.J. Hernández-Peón, “A neurophysiologic model of dreams and hallucinations”, J.Nerv.Ment.Dis. 141:623, 1966

    Article  Google Scholar 

  21. D.E. Rosenberg, A.B. Wolbach,Jr., E.J. Miner and H. Isbell, “Observations on direct and cross tolerance with LSD and D-Amphetamine in man”, Psychophannacologia (Berl.) 3:1, 1963

    Article  Google Scholar 

  22. F.W. Hebbard and R. Fischer, “Effect of psilocybin, LSD and mescaline on small, involuntary eye movements”, Psychopharmacologia (Berl.) 9:146, 1966

    Article  Google Scholar 

  23. R. Fischer, “Sympathetic excitation and biological chronometry”, Internat.J.Neuropsychiat. 2:ll6, 1966

    Google Scholar 

  24. E. Rothlin, “Pharmacology of Lysergic Acid Diethylamide and some ot its related compounds”, J.Pharm.Phamicol. 9:569, 1957

    Article  Google Scholar 

  25. R.M. Slivka and D. Landis, “Effect of LSD-25 on activity level of the hooded rat”, Psychol.Reps. 20:158, 1967

    Article  Google Scholar 

  26. G.C. Walters and P.D. Cooper, “Alicyclic analogue of mescaline” Nature 218:298, 1968

    Article  PubMed  Google Scholar 

  27. L. Noteboom, “Experimental catatonia by means of derivatives of mescaline and adrenaline”, Proc. Roy.Acad.Sci.(Amsterdam) 37:562, 1934

    Google Scholar 

  28. R. Michaux and W.G. Verly, “Action Catalepsigène des Ethers Methyliques des Mono- et Polyphenolamines”, Life Sci. 3:175–183, 1963

    Article  PubMed  Google Scholar 

  29. A.M. Ernst, “Relation between the action of Dopamine and Apomorphine and their 0-methylated derivatives upon the CNS”, Psychopharmacologia 7:391, 1965

    Article  PubMed  Google Scholar 

  30. A. Hofmann, “Psychotomimetic agents” In: Chemical Constitution and Pharmacodynamic Action. 11: Drugs Affecting the Central Nervous System, A.Burger, ed., New York, M. Dekker, 1968

    Google Scholar 

  31. W. Dement and N. Kleitman, “Cyclic variations in EEG during sleep and their relation to eye movements, body motility, and dreaming” Electroenceph.clin.Neurophysiol. 9:673, 1957

    Article  PubMed  Google Scholar 

  32. M.L. Reite and G.V. Pegrsun, “Cortical temperature during paradoxical sleep in the monkey”, Electroenceph.clin.Neurophysiol. 25:36, 1968

    Article  PubMed  Google Scholar 

  33. M. Jouvet and D. Jouvet, “A study of the neurophysiological mechanisms of dreaming” In: The Physiological Basis of Mental Activity. R.H. Peón, ed., New York, Elsevier, 1963

    Google Scholar 

  34. J. Larson and D. Foulkes, “Electromyogram suppression during sleep, dream recall, and orientation time”, Psychophysiol. 5: 548, 1969

    Article  Google Scholar 

  35. B.J. Baldridge, R.M. Whiteman and M.Kramer, “The concurrence of fine muscle and rapid eye movements during sleep”, Psychosomat.Med. 27:19, 1965

    Google Scholar 

  36. G.R. Reding, W.C. Rubright, A. Rechtschaffen and R.S. Daniels, “Sleep pattern of tooth-grinding: its relationship to dreaming” Science l45:725, 1964

    Article  PubMed  Google Scholar 

  37. L. Goldstein, A.A. Sugarman, H. Stolberg, H.B. Murphree and C.C. Pfeiffer, “Electro-cerebral activity in schizophrenics and non-psychotic subjects: quantitative EEG amplitude analysis”, Electroenceph.clin.Neurophysiol. 19:350, 1965

    Article  PubMed  Google Scholar 

  38. H.S. Ephron and P. Carrington, “Rapid eye movement, sleep, and cortical homeostasis”, Psychol.Rev. 73:500, 1966

    Article  PubMed  Google Scholar 

  39. W.C. Dement, “An essay on dreams: The role of physiology in Tonderstanding their nature”, In: New Directions in Psychology II, New York, Holt, Rinehart and Winston, Inc., 1965

    Google Scholar 

  40. R. Fischer, T. Kappeler, P. Wisecup and K. Thatcher, “Measurement of handwriting area to pressure ratios during psilocybininduced hallucinations”, Agents and Actions 1:42, 1969

    Article  PubMed  Google Scholar 

  41. R. Fischer and D. Warshay, “Psilocybin-induced. autonomic, perceptual and behavioral change”, Pharmakopsychiat. Neuropsychopharmakol. (Thieme, Stuttgart) 1:291, 1968

    Article  Google Scholar 

  42. P. Gwynne, R. Fischer and R. Hill, “Hypnotic induction of the interference of psilocybin with optically induced spatial distortion”, Pharmakopsychiat.Neuropsychopharmakol. (Thieme, Stuttgart) 2: 1969

    Google Scholar 

  43. R. Fischer, P. Marks, R. Hill and M. Rockey, “Personality structure as the main determinant of drug-induced (model) psychoses”, Nature (London) 218:296, 1968

    Article  Google Scholar 

  44. R. Fischer, T. Kappeler, P. Wisecup and K. Thatcher, “Personality trait-dependent psychomotor performance under psilocybin”, Dis.Nerv.Syst,, in press, 1970

    Google Scholar 

  45. R. Fischer, “Psychotomimetic drug-induced changes in space and time”, Proc. 4th Intl.Cong.Pharmcol., July l4-l8, 1969 Basel, in press in the Proceedings, Vols.2 and 3, Benno Schwa-be, Basel, 1970

    Google Scholar 

  46. Thomas Acquinas, “Summa Theologica I” qu. 5, art. 4, ad.l

    Google Scholar 

  47. M. Lindahl, “On transitions from perceptual to conceptual learning” Scand.J.Psychol. 9:206, 1968

    Article  Google Scholar 

  48. J. Antrobus, “Information theory and stimulus-independent thought”, Brit.J.Psychol. 59:423, 1968

    Article  Google Scholar 

  49. J. Gibson, “Sense perception and knowledge”, Abstracts of papers presented at 3rd Intl.Cong. of the Logic, Methodology and Philosophy of Science, Amsterdam, August 25-September 2, 1967

    Google Scholar 

  50. L. Stone, “Bases for psychiatric prognostic favorability judgments: psychophysical power functions?”, Behavior.Sci. l4:133, 1969

    Article  Google Scholar 

  51. R. Hill, R. Fischer and D. Warshay, “Effects of excitatory and tranquilizing drugs on visual perception. Spatial distortion thresholds”, Experientia, 25:171, 1969

    Article  PubMed  Google Scholar 

  52. A. Sollberger, “A study of biological variation”, Acta Anat. 22: 127, 1954

    Article  PubMed  Google Scholar 

  53. H. Abramson, M. Jarvik, M. Kaufman, C. Kornetsky, A. Levine and M. Wagner, “Lysergic acid diethylamide (LSD-25): I. Physiological and perceptual responses”,J.Pyschol. 39:3, 1955

    Article  Google Scholar 

  54. R. Corlis, G. Splaver, P. Wisecup and R. Fischer, “Myers-Briggs type personality scales and their relation to taste acuity”, Nature 2l6:91, 1967

    Article  PubMed  Google Scholar 

  55. R. Fischer, “Out on a (phantom) limb, variations on the theme: Stability of body image and the golden section”, Perspect. Biol.Med. 12:259, 1969

    PubMed  Google Scholar 

  56. D. MacKinnon, “Paper presented at Annual Meeting of the Western Psychological Association”, Honolulu, June 14–19, 1965

    Google Scholar 

  57. D. MacKinnon, “The nature and nurture of creative talent” In: Personality Assessment. B Semeonoff, ed., Penguin Books, Baltimore, 1966

    Google Scholar 

  58. R. Fischer, S. England, R. Archer and R. Dean: “Psilocybin reactivity and time contraction as measured by psychomotor performance”, Arzneim.Forsch. l6:l80, 1966

    Google Scholar 

  59. J. Lhermitte, “Les Hallucinations”, G. Doin and Co., Paris, 1951

    Google Scholar 

  60. R. Fischer, “The perception-hallucination continuum” (a reexamination) Dis.Nerv.Syst. 30:l6l, 1969

    PubMed  Google Scholar 

  61. R. Fischer, “On creative, psychotic and ecstatic states”, In: Psychiatry and Art, 2, Art Interpretation and Art Therapy I., Jakab, ed., Karger, Basel, 1969

    Google Scholar 

  62. R. Fischer, “Ueber das rhythmisch Ornamentale im halluzinatorisch Schoepferischen”, 6th Intl.Colloqu.Intl.Soc.Art and Psychopathol., Linz, Sept. 26–28, 1969, Confin.Psychiat. (in press)

    Google Scholar 

  63. K. Behanan, “Yoga, a scientific evaluation”, Dover, New York, 1937

    Google Scholar 

  64. A. Kasamatsu and T. Hirai, “An electroencephalographic study on the zen meditation (zazen)”, Folia Psychiat.Neurol.Japon. 20:315, 1966

    Google Scholar 

  65. B. Anand, G. Chhina and B. Singh, “Some aspects of electroencephalographic studies in yogis”, Electroenceph.clin.Neurophysiol. 13:452, 1961

    Article  Google Scholar 

  66. R. Pritschard, W. Heron and D. Hebb, “Visual perception approached by the method of stabilized images”, Canad.J.Psychol. l4:67, 1960

    Article  Google Scholar 

  67. K. Gaarder, R. Loresko and W. Kropfl, “The phasic relation of a component of alpha rhythm to fixation saccadic eye movements”, Electroenceph.Clin.Neurophysio. 21:544, 1966

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Dept. of Psychiatry, Div. of Behavioral Sciences, The Ohio State University, Upham Hall, Columbus, Ohio, USA

    R. Fischer

Authors
  1. R. Fischer
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Research Institute, Brooklyn State Hospital, 681 Clarkson Avenue, 11203, Brooklyn, N.Y., USA

    Wolfram Keup M.D. (Director of Research, Associate Cinical Professor of Psychiatry,Speaker and EPRA Program Chairman and President Elect.) (Director of Research, Associate Cinical Professor of Psychiatry,Speaker and EPRA Program Chairman and President Elect.)

  2. Department of Psychiatry, State University of New York, Downstate Medical Center, College of Medicine, Brooklyn, New York, USA

    Wolfram Keup M.D. (Director of Research, Associate Cinical Professor of Psychiatry,Speaker and EPRA Program Chairman and President Elect.) (Director of Research, Associate Cinical Professor of Psychiatry,Speaker and EPRA Program Chairman and President Elect.)

Rights and permissions

Reprints and permissions

Copyright information

© 1970 Springer Science+Business Media New York

About this chapter

Cite this chapter

Fischer, R. (1970). Prediction and Measurement of Perceptual-Behavioral Change in Drug-Induced Hallucinations. In: Keup, W. (eds) Origin and Mechanisms of Hallucinations. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-8645-6_27

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-8645-6_27

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-8647-0

  • Online ISBN: 978-1-4615-8645-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation