Abstract
Adrenocorticotropic hormone (ACTH), a linear polypeptide (figure 1) of the anterior lobe of the pituitary, is responsible for a variety of important biologic functions in mammalians. Among these, steroidogenesis at the adrenal cortex and activity at the central nervous system have been most extensively studied (1–3). The 4–10 part of the ACTH sequence, Met-Glu-His-Phe-Arg-Trp-Gly, is present also in the primary structure of the biogenetically related hormones αMSH, βMSH, β- and γ-lipotropins, with which ACTH features in common melanotropic and lipolytic activities (1, 2).
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© 1986 Birkhäuser Boston, Inc.
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Toma, F., Dive, V., Löw, M., Kisfaludy, L. (1986). Proton NMR Studies of the Active Centre of ACTH. In: Niccolai, N., Valensin, G. (eds) Advanced Magnetic Resonance Techniques in Systems of High Molecular Complexity. Progress in Inorganic Biochemistry and Biophysics, vol 2. Birkhäuser Boston. https://doi.org/10.1007/978-1-4615-8521-3_11
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DOI: https://doi.org/10.1007/978-1-4615-8521-3_11
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