The metabolism of diene-organochlorine (cyclodiene) insecticides

  • G. T. Brooks
Conference paper
Part of the Reviews of Environmental Contamination and Toxicology book series (RECT, volume 27)


Following the emergence of insect resistance to the cyclodiene insecticides, and on account of residue problems leading to questions concerning their effects on man, on wildlife, and on the environment, the fate of these compounds in living organisms has come under increasingly close scrutiny. As a result of this concern much effort has been directed toward investigations of the dynamics of their behaviour in the environment and of their metabolic fate, especially since about 1960. Until then it was generally assumed that apart from the already well known epoxidation reactions of chemicals such as aldrin,1 these compounds were rather inert biologically.


Liver Microsome Mosquito Larva Epoxide Ring Epoxidation Reaction Heptachlor Epoxide 
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Copyright information

© Springer-Verlag New York Inc. 1969

Authors and Affiliations

  • G. T. Brooks
    • 1
  1. 1.Biochemistry Department, Pest Infestation LaboratoryAgricultural Research CouncilSloughEngland

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