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Residue Reviews/Rückstands-Berichte pp 74–95Cite as

The determination of penicillins and chlortetracycline in premixes and mixed feeds

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Part of the book series: Reviews of Environmental Contamination and Toxicology ((RECT,volume 7))

Abstract

The feeding of streptomycin during nutritional studies with chicks by Moore et al. (1946) showed a reduction in coliforms in the feces. These workers could not account for the increased growth of the chicks. Newell et al. (1947), who conducted a study of the nutritional value of dried penicillium mycellium, observed excellent growth of chicks and attributed it to the protein and vitamin content of the feed ration. Harned and coworkers (1948) reported an increased growth rate of chicks fed chlortetracycline. Coates et al. (1952 and 1953), Hill et al. (1953), Lillie et al. (1953), and Waibel et al. (1954) concluded that the function of the antibiotic was not the direct stimulation of growth but rather the minimizing of various factors which suppress growth.

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References

  • Alicino:, J. F.: Iodometric method for the assay of penicillin préparations. Anal. Chem. 18, 619 (1946).

    Google Scholar 

  • Barnes:, R. B., R. C. Gore, F. F. Williams, and S. G. Linsley: Infrared analysis of crystalline penicillins. Anal. Chem. 19, 620 (1947).

    Article  CAS  Google Scholar 

  • Beloff:-Chain, A., and F. D. D’Accadia: Chemical method of determinating penicillin in culture fluids. Analyst 77, 423 (1952).

    Article  CAS  Google Scholar 

  • Bliss:, G. I.: The statistics of bioassay. New York: Academic Press 1952.

    Google Scholar 

  • Bond:, C. R., L. J. Bellamy, A. R. Graham, L. Henschall, L. E. V. Horsley, and G. F. Hall: Determination of total penicillin by the iodometric method. Analyst 74, 550 (1949).

    Article  CAS  Google Scholar 

  • Boxer:, G. E., and D. M. Everett: Colorimetric determination of benzyl penicillin. Colorimetric determination of total penicillins. Anal. Chem. 21, 670 (1949).

    Article  CAS  Google Scholar 

  • Brunner:, R., and H. Margreiter: Determination of penicillin in penicillin-containing feeds. Österr. Chem.-Ztg. 36, 8 (1955).

    Google Scholar 

  • Chiccarelli:, F. S., M. H. Woolford, and R. W. Trombitas: The colorimetric determination of chlortetracycline hydrochloride in feed supplements, veterinary therapeutics and food preservatives. J. Assoc. Official Agr. Chemists 40, 922 (1957).

    CAS  Google Scholar 

  • Coates:, M. E.: The mode of action of antibiotics in animal nutrition. Chem. & Ind. 50, 1333 (1953).

    Google Scholar 

  • Coates:, M. E., C. D. Dickinson, G. F. Harrison, S. K. Kon, J. W. G. Porter, S. H. Cummins, and W. F. J. Cuthbertson: A mode of action of antibiotics in chick nutrition. J. Sci. Food Agr. 3, 43 (1952).

    Article  CAS  Google Scholar 

  • Coates:, M. E., G. F. Harrison, S. K. Kon, J. W. G. Porter, and S. T. Thompson: Antibiotics in chick nutrition and vitamin A metabolism. Chem. & Ind. 7, 149 (1952).

    Google Scholar 

  • Colon:, A. A., G. F. Herpich, J. D. Neuss, and H. A. Frediani: The assay of relatively pure benzyl penicillin by UV absorption. J. Amer. Pharm. Assoc. 38, 138 (1949).

    Article  CAS  Google Scholar 

  • Coy:, N. H., C. W. Sabo, and R. J. Keeler: Infrared assay of procaine salt of benzyl penicillin. Anal. Chem. 21, 669 (1949).

    Article  CAS  Google Scholar 

  • Esposito:, R. G., and W. L. Williams: A method for the assay of penicillin in animal feeds. Proc. Soc. Expt. Biol. (N. Y.) 81, 660 (1952).

    CAS  Google Scholar 

  • Esposito:, R. G., and W. L. Williams: Stability of various penicillin salts used for growth promotion in animal feeds. Federation Proc. 11, 208 (1952).

    Google Scholar 

  • Feldman:, D. H., H. S. Kelsey, and J. C. Cavagnol: Fluorometric determination of chlortetracycline. Anal. Chem. 29, 1696 (1957).

    Google Scholar 

  • Ford:, J. H.: Hydroxylamine method of determining penicillins. Anal. Chem. 19, 1004 (1947).

    Article  CAS  Google Scholar 

  • Gavin:, J. J.: The diffusion method. Applied Microbiol. 5, 25 (1957).

    CAS  Google Scholar 

  • Gavin:, J. J.: The turbimetric method. Applied Microbiol. 5, 235 (1957).

    CAS  Google Scholar 

  • Grady:, J. E., and W. L. Williams: Determination of aureomycin in feeds by the pad-plate method. Antibiotics and Chemotherapy 3, 158 (1953).

    CAS  Google Scholar 

  • Grenfell:, J. C., J. A. Means, and E. U. Brown: Studies on the naturally occurring penicillins, an assay method for penicillin G. J. Biol. Chem. 170, 527 (1947).

    CAS  Google Scholar 

  • Harned:, B. K, W. C. Raymond, M. C. Clark, R. Cosgrove, C. H. Hine, W. J. McCanley, E. Stokey, R. E. Vessey, N. H. Yuda, and Y. Gubbarow: Pharmacology of duomycin. Ann. N. Y. Acad. Sci. 51, 182 (1948).

    Article  PubMed  CAS  Google Scholar 

  • Herriot:, R.: A spectrophotometric method for the determination of penicillin. J. Biol. Chem. 164, 725 (1946).

    Google Scholar 

  • Hill:, D. C., H. D. Bronion, S. J. Slinger, and G. W. Anderson: Influence of environment on the growth response of chicks to penicillin. Poultry Sci. 32, 462 (1953).

    Google Scholar 

  • Hiscox:, D. J.: Chemical assay of crystalline penicillins. Anal. Chem. 21, 658 (1949).

    Article  CAS  Google Scholar 

  • Hiscox:, D. J.: The ultraviolet determination of aureomycin and terramycin. J. Amer. Pharm. Assoc. 40, 237 (1951).

    Article  CAS  Google Scholar 

  • Katz:, S. E.: Comparison of chemical and microbiological methods for the determination of procaine penicillin in premixes and mixed feeds. J. Assoc. Official Agr. Chemists 46, 429 (1963).

    CAS  Google Scholar 

  • Katz:, S. E., and J. Spock: Unpublished results (1963).

    Google Scholar 

  • Katz:, S. E., and A. G. Winnett: Colorimetric determination of procaine penicillin in premixes. J. Agr. Food Chem. 10, 284 (1962).

    Article  Google Scholar 

  • Kelsey:, H. S., M. Day, C. T. DiGrado, and A. Bodden: The determination of aureomycin in feeds. J. Assoc. Official Agr. Chemists 35, 828 (1952).

    CAS  Google Scholar 

  • Kersey:, R. C., and F. U. Leghorne: A microbiological assay of penicillin in animal feeds. Appl. Microbiol. 1, 150 (1953).

    PubMed  CAS  Google Scholar 

  • Levine:, J., E. A. Garlock, and FL Fischbach: A chemical assay of aureomycin. J. Amer. Pharm. Assoc. 38, 473 (1949).

    Article  CAS  Google Scholar 

  • Levy:, G. B., D. Fergus, and J. M. Caldas: Benzylpenicillin content of broth; Estimation by a gravimetric procedure. Anal. Chem. 21, 664 (1949).

    Article  CAS  Google Scholar 

  • Levy:, G. B., D. Shaw, E. S. Parkinson, and D. Fergus: Determination of penicillin G; Spectrophotometry method. Anal. Chem. 20, 1159 (1948).

    Article  CAS  Google Scholar 

  • Lillie:, R. J., J. R. Sizemore, and H. R. Bird: Environment and stimulation of growth of chicks by antibiotics. Poultry Sci. 32, 466 (1953).

    Google Scholar 

  • Mader:, W. J., and R. R. Buck: Chemical assay for crystalline benzylpenicillin. Anal. Chem. 20, 284 (1948).

    Article  CAS  Google Scholar 

  • Moore:, P. R., A. Evenson, T. D. Luckey, E. McCoy, C. A. Elvehjem, and E. B. Hart: Use of sulfasuxidine, streptothricin, and streptomycin in nutritional studies with the chick. J. Biol. Chem. 165, 437 (1946).

    PubMed  CAS  Google Scholar 

  • Mundell:, M., H. Fischbach, and T. E. Eble: Chemical assay of penicillin. J. Amer. Pharm. Assoc. 35, 373 (1946).

    Article  CAS  Google Scholar 

  • Newell:, G. W., W. H. Peterson, and C. A. Elvehjem: The value of dried penicillin mycellium as a supplement in practical chick rations. Poultry Sci. 26, 284 (1947).

    CAS  Google Scholar 

  • Official Methods of Analysis, Association of Official Agricultural Chemists, 9th Ed. 1960.

    Google Scholar 

  • Örtenblad, B.: Iodometric and polarometric determination of penicillin. Acta Chem. Second 4, 518 (1950).

    Article  Google Scholar 

  • Pan:, S. C.: Simultaneous determination of penicillin and penicilloic acid in fermentation samples by a colorimetric method. Anal. Chem. 26, 1438 (1954).

    Article  CAS  Google Scholar 

  • Pedersen:, V.: Iodometric determination of penicillin. Arch. Pharm. Chem. 55, 625 (1948).

    CAS  Google Scholar 

  • Perlman:, D.: Colorimetric method for determination of aureomycin, carbomycin, erythromycin and terramycin in aqueous solution. Science 118, 628 (1953).

    Article  PubMed  CAS  Google Scholar 

  • Philpotts:, A. R., W. Thain, and G. H. Twigg: Spectroscopic estimation of penicillin G. Nature 159, 839 (1947).

    Article  PubMed  CAS  Google Scholar 

  • Randall:, W. A., and J. M. Burton: Report on antibiotics in animal feeds. J. Assoc. Official Agr. Chemists 40, 857 (1957).

    CAS  Google Scholar 

  • Ravin:, L. J., and A. E. James: A spectrophotometric assay for aureomycin hydrochloride. J. Amer. Pharm. Assoc. 44, 215 (1955).

    Article  CAS  Google Scholar 

  • Saltzman:, A.: Fluorophotometric estimation of aureomycin in blood and urine. J. Lab. Clin. Med. 35, 123 (1950).

    PubMed  CAS  Google Scholar 

  • Snell:, N. S., and J. C. Lewis: Error caused by stainless-steel cylinders in plate bio-assays. Antibiotics and Chemotherapy 9, 609 (1959).

    PubMed  CAS  Google Scholar 

  • Spock:, J., and S. E. Katz: Fluorometric determination of chlortetracycline in premixes. J. Assoc. Official Agr. Chemists 46, 434 (1963).

    CAS  Google Scholar 

  • Stiffey:, A. V., and W. L. Williams: The separation of aureomycin, chlortetracycline and oxytetracycline in feeds by paper chromatography. J. Assoc. Official Agr. Chemists 38, 870 (1955).

    CAS  Google Scholar 

  • Stock:, F. E.: Spectrophotometric estimation of total penicillins by conversion to penicillenic acid and the importance of copper in controlling the reaction. Analyst 79, 662 (1954).

    Article  CAS  Google Scholar 

  • Stokstad:, E. L. R.: Antibiotics in animal nutrition. Physiol. Rev. 34, 25 (1954).

    PubMed  CAS  Google Scholar 

  • Tanguay:, A. E., A. R. Bogert, and M. H. Blanchard: Problems in the assay of chlortetracycline in feeds. Antibiotics and Chemotherapy 9, 167 (1959).

    CAS  Google Scholar 

  • Tanguay:, A. E., S. Friedman, and V. Kiremidjian: Microbiological procedure for determination of aureomycin, chlortetracycline hydrochloride in feed supplements and finished feeds. American Cyanamid tech. Bull. No. 17 (1957).

    Google Scholar 

  • Waibel:, P. E., O. J. Abbot, C. A. Banmann, and H. R. Bird: Disappearance of the growth response of chicks to dietary antibiotics in an “old” environment. Poultry Sci. 33, 1141 (1954).

    Google Scholar 

  • Werthleim:, A. A.: Colorimetric method for penicillin with hydroxylamine and ferric ion. Application to penicillin preparation and fermentation broths. Med. Doswiadczalna i Microbial 7, 419 (1955).

    Google Scholar 

  • Williams:, W. L., R. G. Esposito, and E. L. R. Stokstad: Comparison of the chick and microbiological methods for assay of penicillin in feeds. Federation Proc. 12, 290 (1953).

    Google Scholar 

  • Wornick:, R. C., and G. O. Kuhn: Microscopical and chemical identification of antibiotics used in feed products. Sixth Annual Meeting, Amer. Assoc. Feed Microscopists June, 1958.

    Google Scholar 

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Authors and Affiliations

  1. New Jersey Agricultural Experiment Station, Rutgers, the State University, New Brunswick, New Jersey, USA

    Stanley E. Katz & Kenneth Helrich

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  1. Stanley E. Katz
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  2. Kenneth Helrich
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Editors and Affiliations

  1. Riverside, USA

    Francis A. Gunther

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© 1964 Springer-Verlag Berlin · Göttingen · Heidelberg

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Katz, S.E., Helrich, K. (1964). The determination of penicillins and chlortetracycline in premixes and mixed feeds. In: Gunther, F.A. (eds) Residue Reviews/Rückstands-Berichte. Reviews of Environmental Contamination and Toxicology, vol 7. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-8389-9_5

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  • DOI: https://doi.org/10.1007/978-1-4615-8389-9_5

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4615-8391-2

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