Abstract
An important place among the most important problems in studying the influence of chemicals on the organism is occupied by the questions of their influence on the higher nervous activities.
Translated for Residue Reviews by Professor Peter G. Rossbacher. Translation very kindly read and corrected for specialized terminology by Dr. Lloyd W. Hazleton and Dr. Travis I. Thompson.
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References
Aleksandrov, I. S.: Changes in the production of saliva under a chronic poisoning by lead. Physiol. J. USSR. 5, 996 (1938).
Aleksandrov, I. S., and M. G. Cybina: Some data concerning the influence of shale gasoline on the conditioned reflexes of mice. Data concerning the toxicology of shale-products 1, 48 (1947) (Leningrad).
Anonymous: Official FDA tolerances. National Agr. Chemicals Assoc. News and Pesticide Reviews 18 (No. 3), 3 (1960).
Anonymous: Threshold limit values for 1961 adopted at the 23rd annual meeting of the American Conference of Governmental Industrial Hygienists, Detroit, Michigan, April 9–12. Environmental Health 3 (No. 4), 489 (1961).
Antonovic, E. A.: Data concerning the toxicological-hygienic characteristics of gamma-hexachlorocyclohexane BHC and the establishment of tolerance limits in food products. Dissertation, Kiev (1959).
Citovic, I. S.: The procedure of studying the effect of oil products on the organism of animals. Works N. Caucasian Regional Inst, of Work Safety 1, 92 (1930).
Citovic, I. S.: The influence of acetone on the central nervous system. In: Works Rostov Scientific Research Inst, of Work Safety. Collection of Works Concerning Toxicology 2, 48 (1935).
Citovic, I. S.: Chronic poisoning and higher nervous activities. Abstr. Reports 5th Meeting Concerning Physiological Problems, devoted to memory of Pavlov. P. 86. Moscow 1939.
Dubois, K., and J. M. Coon: Toxicology of organophosphorus insecticides in mammals. Arch. Ind. Hyg. 6 (No. 1), 9 (1952).
Forster, F., and R. Mccarter: Spread of acetylcholine induced electrical discharge of the cerebral cortex. Amer. J. Physiol. 144, 168 (1945).
Frolov, Iu. P.: The influence of some poisons on the central nervous system and the higher nervous activities. In: The influence of certain poisons on the higher nervous activities 10, 5 (1938) ( Moscow: VSCHI).
Frolov, Iu. P.: The higher nervous activities in toxicoses. Moscow: Medgiz 1944.
Frolov, Iu. P., L. S. Gorsheleva, and P. I. Polianskii: The influence of carbonmonoxide on the higher nervous activities. Abstr. Reports 7th Meeting Concerning Physiological Problems, devoted to memory of Pavlov. P. 20. Moscow 1950.
Gal’Perin, S. I., and G. I. Kuz’Menko: The effect of acetylcholine on the central nervous system. Thesis of reports 13th meeting concerning a physiological problem, dedicated to Pavlov. P. 30 (1948).
Gershon, S., and F. H. Shaw: Psychiatric sequelae of chronic exposure to organophosphorus insecticides. Lancet 1, 1371 (1961).
Gimadeev, M. M.: The effect of fumes of mercury on producing conditioned reflexes of rabbits. Pharmacol. Toxicol. 2, 136 (1962).
Golubev, A. A.: The study of the rate of developing conditioned reflexes in mice under a long poisoning by fumes of acetone and xylol. Works of scientific section devoted to results of work in 1957. Leningrad 1959.
Grigor’Ev, Z. E.: Hygienic problems concerning the production of artificial liquid fuel. Autoreport, Leningrad 1956.
Grigor’Ev, Z. E.: The application of the method of conditioned reflexes for toxicological purposes. Theses 5th Leningrad conference concerning questions of industrial toxicology (1957).
Il’Iucenko, R. Iu., and M. D. Mashkovskij: The interaction of anticholinesterase agents with choline and adrenolytic agents in the field of reticular formation. Pharmacol. Toxicol. 4, 403 (1961).
Ivanov-Smolenskij, A. G.: Essays on the pathophysiology of higher nervous activities. Moscow: Medgiz 1952.
Izergina, A. Iu.: The effect of arsenic on the nervous system of young animals. In: The influence of certain poisons on the higher nervous activities 10, 121 (1938 a) (Moscow: VSCHI).
Izergina, A. Iu.: New data concerning the question of the effect of cyanide compounds on the central nervous system. First information concerning the influence of certain poisons on the higher nervous activities 10, 18 (1938b) ( Moscow: VSCHI).
Izergina, A. Iu.: The effect of a repeated poisoning by sodium cyanide on the higher nervous activities of animals (second issue). In: The influence of certain poisons on the higher nervous activities 10, 61 (1938 c) (Moscow: VSCHI).
Izergina, A. Iu.: The effect of acetylcholine on the higher nervous activities of white rats. Rept. Sci. Res. Studies Med. Biol. Sci. 7, 121 (1949).
Kagan, Iu. S.: The toxicology of a number of organophosphorus insecticides and work-hygiene with their application. Dissertation, Kiev (1961).
Kagan, Iu. S.: The effect of thiophosphates on the conditioned reflexes and the cholinesterase activities of cats. J. Higher Nervous Activities 12 (No. 3), 530 (1962).
Kagan, Iu. S., E. I. Spynu, and N. K. Stacek: Changes in the activities of conditioned reflexes and the cholinesterase activity of blood in animals under the influence of different organophosphorus insecticides. Works of the scientific session in honor of the 30th anniversary of the Institute of Work Hygiene. P. 92. Kiev (1958).
Karpov, B. D.: Data for the establishment of threshold doses of organophosphorus insecticides under oral introduction. Works Leningrad Med. Inst. Sanit. Hyg. 62, 52 (1960).
Kaloyanova-Simeonova, F. P.: Effect du chlortion sur les reflexes moteurs conditionel des rats albinos. Activ. nerv. sup. (Praha) 3, 3 (1961).
Kosanova, L. V.: Data concerning the toxicology of the new insecticide chlorindane and its tolerance limits. Dissertation, Kuibyshev (1957).
Kotliarevskii, L. I.: The effect of an experimental disruption of the higher nervous activities on the course of the neurointoxication in animals. J. Higher Nervous Activities 3, 405 (1951 a).
Kotliarevskii, L. I.: The procedure of studying conditioned motor reflexes in some small animals (white rats and guinea pigs). J. Higher Nervous Activities 5, 753 (1951 b).
Krasnov, S. K.: Disturbances of higher nervous activities through poisoning of animals by phosphorus. J. Higher Nervous Activities 4, 558 (1954).
Krasnov, S. K.: Disturbances of the higher nervous activities through chronic poisoning of animals by phosphorus. J. Higher Nervous Activities 4, 600 (1957).
Kresbach, H.: Schwere DDT Dermatitis mit erheblicher Storung des Allgemeinbefindens und Symptomen von Seiten innerer Organe. Klin. Wschr. (Wien) 27, 559 (1953).
Lisovskaia, E. V.: Experimental data for determining the permissible concentration limits of metaphos in drinking water. Hyg. and Sanit. 12, 19 (1958).
Macintosh, F., and P. Oborin: Release of acetylcholine from the intact cerebral cortex. Abstr. XIX Intern. Physiol. Congress Montreal. P. 580 (1953).
Makrosian, A. A.: The influence of choline and acetylcholine on the chronaxy of the motor zone of the cerebral cortex. Bull. expt. Biol. Med. 4 (No. 2), 119 (1937).
Medved’, L. I.: Work hygiene under the influence of organomercury fungicides. Dissertation 1960.
Medved’, L. I., Iu. S. Kagan, and E. I. Spynu: Experimental data concerning the reflex mechanism of the action of organomercury and organophosphorus insectofungicides. VIII Union Congress Physiol. Abstr. Reports p. 40. Moscow 1955.
Michel’Son, M. Ia.: The physiological role of acetylcholine and the finding of new drugs. Leningrad 1957.
Michel’Son, M. Ia., E. K. Rožkova, and N. V. Cavateev: The antagonistic effect of cholinolytic and anticholinesterase agents on the higher nervous activities. Bull. expt. Biol. Med. 2, 7 (1954).
Naumov, S. F.: Abstr. Reports 13th Meeting Concerning Problems of Physiology, devoted to memory of academician Pavlov. P. 70 (1948).
Nikiforovskij, P. M.: The influence of neurodrugs on the conditioned reflexes. Works Assoc. Russian Physicians. Petersburg 1910.
Osetrov, V. I.: Materials about the toxicology and hygiene establishment of tolerance limits for the new insecticide heptachlor. Dissertation, Kiev (1959).
Pavlov, I. P.: Complete edition of his works 1, 387 (1940).
Rožkova, E. K.: The antagonistic effect of cholinolytic and anticholinesterase agents on the conditioned reflexes of dogs. In: The physiological role of acetylcholine and the finding of new drugs. Leningrad 1957.
Rusin, N. M., and G. P. Andronova: The hygienic evaluation of food products treated with parathion. Hyg. and Sanit. 10, 28 (1954 a).
Rusin, N. M., and G. P. Andronova: The hygienic evaluation of food products treated with hexachlorane and DDT. Hyg. and Sanit. 6, 34 (1954 b).
Rusin, N. M., and G. P. Andronova, and O. I. Vasil’Eva: The hygienic evaluation of food cultures treated with metaphos. Hyg. and Sanit. 1, 46 (1957).
Savateev, N. V.: The antagonistic effect of colinolytic and anticholinesterase agents on the activities of conditioned reflexes in white rats. In: The physiological role of acetylcholine and the finding of new drugs. P. 57. Leningrad 1957 a.
Savateev, N. V.: The influence of anticholinesterase and cholinolytic agents on the speed of forming conditioned reflexes. In: The physiological role of acetylcholine and the finding of new drugs. P. 57. Leningrad 1957 b.
Serebrianaia, S. G.: The mode of action of DDT. Abstr. Reports XIII Union Congress of Physiologists, Biochemists, and Pharmacologists. Pp. 540—541. Moscow: Ed. by Acad. Sci. USSR 1955.
Spiotta, E. J.: Aldrin poisoning in man. Arch. Ind. Hyg. Occupational Med. 4, 560 (1951).
Spynu, E. I.: Data concerning the toxicology of the insecticide Niuiph 100 and the establishment of tolerance limits. Dissertation, Kiev (1952).
Spynu, E. I.: The method of an objective registration of the motor feeding conditioned reflexes in cats. Scientific Session to Honor 300th Anniversary Reunification Ukraine with Russia. P. 14. Kiev: Gosmedizdat 1954.
Spynu, E. I.: Experimental data concerning the toxicology of thiophos. Pharmacol. Toxicol. Appendix p. 49 (1957 a).
Spynu, E. I.: The effect of some organophosphorus insecticides in the higher nervous activities and on the cholinesterase activity. In: The chemistry and application of organophosphorus compounds. Moscow: Ed. by Acad. Sci. USSR 1957b.
Spynu, E. I.: Changes in the higher nervous activities and in the functional condition of the upper kidneys under the effect of small doses of insecticides of diene synthesis. Hygiene and toxicology of new pesticides and the clinical treatment of poisonings. Reports 2nd Union Scientific Conference Concerning Study and Regulation of Toxic chemicals. Ed. with L. I. Medved’. Moscow: Medgiz 1962.
Stacek, N. K.: Experimental data concerning the toxicology of methylsystox. Pharmacol. Toxicol. 6, 559 (1959).
Stacek, N. K.: Data concerning the toxicological characteristic of methylsystox and the establishment of tolerance limits. Dissertation, Kiev (1960).
Trynkin, I. I., And A. Iu. Izergina: Some observations concerning the effect of adamsit on the nervous system. In: The influence of certain poisons on the higher nervous activities 10, (1938) ( Moscow: VSCHI).
Val’Dman, A. B.: Some results of a pharmacological study of the reticular formation. Pharmacol. Toxicol. 6, 480 (1960).
Zavadskij, I. V.: The technique of applying the method of conditioned reflexes to pharmacology. Works Assoc. Russian Physicians. Petersburg 1908.
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Medved’, L.I., Spynu, E.I., Kagan, I.S. (1964). The method of conditioned reflexes in toxicology and its application for determining the toxicity of small quantities of pesticides. In: Gunther, F.A. (eds) Residue Reviews / Rückstands-Berichte. Residue Reviews / Rückstands-Berichte, vol 6. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-8386-8_5
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