Abstract
The major limitation to successful organ transplantation remains immunological rejection of the graft by the host. At present, the usual procedure for attempting to control graft rejection is to give immunosuppressive drugs (e.g. cyclosporin). However, such drugs also suppress desirable immune responses and may also have direct toxic effects. To avoid these problems, alternative strategies would be to treat the graft so that it is no longer immunogenic (treated elsewhere in this volume) or to treat the host such that it becomes specifically non-responsive against the graft. This last is the approach taken here.
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© 1993 Birkhäuser Boston
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Miller, R.G. (1993). Induction of Immunological Unresponsiveness in the Adult Animal. In: Bell, E. (eds) Tissue Engineering. Birkhäuser, Boston, MA. https://doi.org/10.1007/978-1-4615-8186-4_20
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DOI: https://doi.org/10.1007/978-1-4615-8186-4_20
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