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Abstract

In 1995, an estimated 1.25 million patients are diagnosed with cancer in the US and the number of predicted cancer deaths is in excess of 540,000 (1). Similar incidences and death rates for the most important cancers are reported from other industrialized Western countries. Most patients diagnosed with cancer will receive one or more chemotherapy regimens during the course of their disease. Retrospective and prospective clinical trials have improved the likelihood of response in individual patients and have been pivotal in the development of curative regimens for patients with a variety of malignancies. These major advances include patients with childhood tumors, testicular cancer, and some types of leukemias and malignant lymphomas. The empiric clinical approach has also led to the development of successful adjuvant therapies for patients with breast cancer, osteogenic sarcomas, and colorectal cancer.

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Hanauske, AR., Hilsenbeck, S.G., Von Hoff, D.D. (1997). Human Tumor Screening. In: Teicher, B.A. (eds) Anticancer Drug Development Guide. Cancer Drug Discovery and Development. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4615-8152-9_3

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  • DOI: https://doi.org/10.1007/978-1-4615-8152-9_3

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4615-8154-3

  • Online ISBN: 978-1-4615-8152-9

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