Abstract
Herpes simplex virus types 1 and 2 (HSV-1, HSV-2) give rise to a variety of human diseases of different severity and morbidity. It is well known that herpes virus remains latent in the human body after the first exposure to the virus (the primary infection) and colonizes either the trigeminal or the sacral ganglia, from where the virus is occasionally reactivated (for review see Wildy et al., 1982). The result of reactivation is either a clinical or a subclinical recurrent infection, and viral cellular proteins synthesized during a primary as well as during a recurrent infection interact with the immune system of the infected host organisms and give rise to the formation of both circulating HSV-specific antibodies and activated lymphocytes that have the potential to eliminate infectious virus from the infected host.
Keywords
- Herpes Simplex Virus
- Herpes Simplex Virus Type
- Genital Herpes
- Human Seron
- Herpes Simplex Virus Infection
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Norrild, B. (1985). Humoral Response to Herpes Simplex Virus Infections. In: Roizman, B., Lopez, C. (eds) The Herpesviruses. The Viruses. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-8021-8_3
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