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Structure and Function of the Circulation pp 427–474Cite as

Arterial Smooth Muscle Cells in Tissue Culture

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Abstract

Smooth muscle cells are among the most remarkable of the mesenchymal cells. They have long been of interest to biologists and physiologists. It is not surprising that they were grown in vitro by Carrell, Maximow, and other pioneers who first cultured diploid cells, since it is relatively easy to grow the cells in pure culture from explants (Carrell and Burrows, 1910; Maximow, 1925). The outgrowths from these explants in turn provide cells which are readily subcultured.

Insofar as the studies summarized in this chapter reflect work performed in this laboratory, we acknowledge the support of the following sources: USPHS Grants HL 7196 and HL 15062, the Heart Research Foundation, Inc., and the Louis A. Block Fund at the University of Chicago.

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Authors and Affiliations

  1. SCOR-Atherosclerosis, University of Chicago, Chicago, IL, 60637, USA

    R. W. Wissler M.D., Ph.D. (Donald N. Pritzker Distinguished Service Professor of Pathology and Director), K. Fischer-Dzoga M.D. (Associate Professor of Pathology and Research Associate) & S. R. Bates Ph.D. (Assistant Professor of Pathology and Research Associate)

  2. Michael Reese Hospital, Chicago, IL, 60616, USA

    R. M. Chen M.D., Ph.D. (Assistant Director of Clinical Pathology)

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Editors and Affiliations

  1. University of Texas Health Science Center, USA

    Colin J. Schwartz M.D., F.R.A.C.P. (Professor of Pathology, Member of Scientific Staff) (Professor of Pathology, Member of Scientific Staff)

  2. Southwest Foundation for Research & Education, San Antonio, Texas, USA

    Colin J. Schwartz M.D., F.R.A.C.P. (Professor of Pathology, Member of Scientific Staff) (Professor of Pathology, Member of Scientific Staff)

  3. Office of Naval Research, Boston, Massachusetts, USA

    Nicholas T. Werthessen Ph.D. (Bioscientist, Senior Research Associate) (Bioscientist, Senior Research Associate)

  4. Brown University, Providence, Rhode Island, USA

    Nicholas T. Werthessen Ph.D. (Bioscientist, Senior Research Associate) (Bioscientist, Senior Research Associate)

  5. Medical Affairs, St. Luke’s Hospital, Bethlehem, Pennsylvania, USA

    Stewart Wolf M.D. (Vice President, Professor of Medicine, Director) (Vice President, Professor of Medicine, Director)

  6. Temple University, Philadelphia, Pennsylvania, USA

    Stewart Wolf M.D. (Vice President, Professor of Medicine, Director) (Vice President, Professor of Medicine, Director)

  7. Totts Gap Institute, Bangor, Pennsylvania, USA

    Stewart Wolf M.D. (Vice President, Professor of Medicine, Director) (Vice President, Professor of Medicine, Director)

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Wissler, R.W., Fischer-Dzoga, K., Bates, S.R., Chen, R.M. (1981). Arterial Smooth Muscle Cells in Tissue Culture. In: Schwartz, C.J., Werthessen, N.T., Wolf, S. (eds) Structure and Function of the Circulation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7927-4_8

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