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Role of Somatostatin in Nutrient Regulation

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Book cover Somatostatin

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 188))

Abstract

Somatostatin-immunoreactive material has been found in D cells of the stomach, small intestine and pancreas (1–6); additionally, it is present in vagal nerve fibres and in neurons of the myenteric and submucosal plexus of the intestinal tract (7–9). Within the gastrointestinal tract and pancreas, an accumulation of D cells has been demonstrated in the fundic and antral area of the stomach and in the islets of Langerhans, whereas a more scattered distribution has been shown in the small and large intestine (10–12). This localization of somatostatin in organs which are exclusively responsible for adequate digestion, absorption and disposal of ingested nutrients raises the possibility that somatostatin might participate in the regulation of nutrient entry from the gastrointestinal tract into the circulation. Thus, somatostatin-containing D cells are in contact with nutrients at all stages of nutrient assimilation.

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Authors and Affiliations

  1. Department of Internal Medicine I, University of Ulm, 7900, Ulm/Donau, Steinhovelstrasse 9, Germany

    V. Schusdziarra

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  1. V. Schusdziarra
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Editors and Affiliations

  1. McGill University and Royal Victoria Hospital, Montreal, Quebec, Canada

    Yogesh C. Patel

  2. McGill University and McGill University-Montreal Children’s Hospital Research Institute, Montreal, Quebec, Canada

    Gloria S. Tannenbaum

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© 1985 Springer Science+Business Media New York

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Schusdziarra, V. (1985). Role of Somatostatin in Nutrient Regulation. In: Patel, Y.C., Tannenbaum, G.S. (eds) Somatostatin. Advances in Experimental Medicine and Biology, vol 188. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7886-4_23

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  • DOI: https://doi.org/10.1007/978-1-4615-7886-4_23

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-7888-8

  • Online ISBN: 978-1-4615-7886-4

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