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Termination of Translation

  • Chapter
Ribosomes

Part of the book series: Cellular Organelles ((CORG))

Abstract

The ribosome reads mRNA triplet by triplet and elongates the polypeptide chain until it comes across one of the following codons: UAA, UAG, or UGA. None of these triplets possess a cognate aminoacyl-tRNA; they all stop translation. Thus, they serve as termination codons (Brenner, Stretton, and Kaplan, 1965; Brenner et al., 1967). UAA is the most frequently used of these codons, whereas UAG is rarely used.

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Authors and Affiliations

  1. Russian Academy of Sciences, Moscow, Russia

    Alexander S. Spirin

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  1. Alexander S. Spirin
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© 1999 Kluwer Academic/Plenum Publishers, New York

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Spirin, A.S. (1999). Termination of Translation. In: Ribosomes. Cellular Organelles. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7817-8_14

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  • DOI: https://doi.org/10.1007/978-1-4615-7817-8_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-46146-0

  • Online ISBN: 978-1-4615-7817-8

  • eBook Packages: Springer Book Archive

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