Abstract
As a result of transpeptidation, the tRNA residue of the newly elongated peptidyl-tRNA occupies the ribosomal A site while deacylated tRNA occupies the P site (Fig. 12.1, left). Translocation is defined as an intraribosomal movement of the bound tRNA residues accompanied by the shift of the template polynucleotide relative to the ribosome. In sum, the tRNA residue of the peptidyl-tRNA moves from the A site to the P site, the deacylated tRNA is displaced from the P site, the template moves a distance of one codon in the 5′-to-3′ direction, and the A site with the new codon becomes vacant (Fig. 12.1, right).
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Spirin, A.S. (1999). Elongation Cycle, Step III: Translocation. In: Ribosomes. Cellular Organelles. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7817-8_12
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DOI: https://doi.org/10.1007/978-1-4615-7817-8_12
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