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Abstract

The research on prostaglandins has developed rapidly during the last 20 years. In addition to the classical prostaglandins (PG), new related compounds have been discovered, among them thromboxane A2 (TXA2), prostacyclin (PGI2), and leukotrienes (LT). Most of them originate from the essential fatty acid arachidonic acid (5,8,11,14-eicosatetraenoic acid), which normally is esterified to cell membrane phospholipids. Following physiological stimuli, arachidonic acid is released and converted to active compounds. This is depicted in Fig. 1.

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Authors and Affiliations

  1. Department of Experimental Alcohol and Drug Addiction Research, Karolinska Institutet Stockholm, Sweden

    Erik Änggård

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  1. Erik Änggård
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Editor information

Editors and Affiliations

  1. Albert Einstein College of Medicine, Bronx, New York, USA

    Marc Galanter

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© 1985 Plenum Press, New York

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Änggård, E. (1985). Overview. In: Galanter, M. (eds) Recent Developments in Alcoholism. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7715-7_7

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  • DOI: https://doi.org/10.1007/978-1-4615-7715-7_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-7717-1

  • Online ISBN: 978-1-4615-7715-7

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