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A RP-HPLC Method for the Measurement of Guanine, Other Purine Bases and Nucleosides

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Part of the Advances in Experimental Medicine and Biology book series (AEMB,volume 309B)

Abstract

A method for the analysis of purine bases and their nucleosides by RP-HPLC has been developed using a procedure similar to that reported in Reference 1. A chromatogram of standard compounds is shown in Figure 1. The method has been employed for the evaluation of purine metabolites in plasma from subjects admitted to the neonatal intensive care unit of the University of Rome (A) and for the study of allopurinol metabolism in human heart (B).

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© 1991 Plenum Press, New York

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Quaratino, C.P. et al. (1991). A RP-HPLC Method for the Measurement of Guanine, Other Purine Bases and Nucleosides. In: Harkness, R.A., Elion, G.B., Zöllner, N. (eds) Purine and Pyrimidine Metabolism in Man VII. Advances in Experimental Medicine and Biology, vol 309B. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-7703-4_9

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  • DOI: https://doi.org/10.1007/978-1-4615-7703-4_9

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