Abstract
Leprosy existed for thousands of years in the preantibiotic era and was treated in many different ways. Among the various treatments, chaulmoogra oil was most widely used. The clinical response, especially among lepromatous cases, to the treatment of chaulmoogra oil was inconsistent and relapse was common, indicating that its therapeutic effect was modest, and this has been confirmed by the modest activity of chaulmoogric acid against M. leprae in the mouse footpad system (1).
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Ji, B. (1998). Treatment of Leprosy. In: Gangadharam, P.R.J., Jenkins, P.A. (eds) Mycobacteria. Chapman & Hall Medical Microbiology Series. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7511-5_15
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