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The Reality and Meaning of Physiological Factors

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Abstract

The term “physiological factor” was introduced by Bazin et al. (1979) for a time-activity curve detected above the separate compartment of a radio-pharmaceutical in the body. Considering formally the elementary time-activity curves recorded in dynamic radionuclide study as vectors then the physiological factors can be regarded as a non-orthogonal base of the corresponding vector space. Under certain restrictive conditions this base can be found by the methods of factor analysis.

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References

  • Barber, D. C. (1980). The use of principal components in the quantitative analysis of gamma camera dynamic studies, Phys. Med. Biol., 25, 283–292.

    Article  Google Scholar 

  • Barber, D. C. and Nijran, K. S. (1982). Factor analysis of dynamic radionuclide studies, in: Nuclear Medicine and Biology, C. Raynaud, ed., Pergamon Press, Paris, 31–34.

    Google Scholar 

  • Bazin, J. P., DiPaola, R., Gibaud, B., Rougier, P. and Tubiana, M. (1979). Factor analysis of dynamic scintigraphic data as a modelling method. An application to the detection of metastases, in: Information Processing in Medical Imaging, R. DiPaola and E. Kahn, eds., INSERM 88, Paris, 345–366.

    Google Scholar 

  • Bazin, J. P. and DiPaola, R. (1982). Advances in factor analysis applications in dynamic function studies, in: Nuclear Medicine and Biology, C. Raynaud, ed., Pergamon Press, Paris, 35–38.

    Google Scholar 

  • Bazin, J. P., DiPaola, R., Aubry, F., Aurengo, A., Capderou, A., Cavailloles, F., Cinotti, L., Herry, J. Y. and Lumbroso, J. (1984). Factor analysis of dynamic structures, Informatek Users Group Newsletter, 1, 3–15.

    Google Scholar 

  • Benzécri, J. P. (1969). Statistical analysis as a tool to make patterns emerge from data, in: Methodologies of Pattern Recognition, S. Watanabe, ed., Academic Press, New York, 35–74.

    Google Scholar 

  • Bierman, G. J. (1977). Factorization Methods for Discrete Sequential Estimation, Academic Press, New York.

    MATH  Google Scholar 

  • Blahus, P. (1985). Factor Analysis and its Generalization (in Czech), SNTL, Prague.

    Google Scholar 

  • Cavailloles, F., Bazin, J. P. and DiPaola, R. (1984). Factor analysis in gated cardiac studies, J. Nucl. Med., 25, 1067–1079.

    Google Scholar 

  • DiPaola, R., Penel, C., Bazin, J. P. and Berche, C. (1975). Factor analysis and scintigraphy, in: Information Processing in Scintigraphy

    Google Scholar 

  • C. Raynaud and A. Todd-Pokropek, eds., Proceedings of the IVth International Conference, Orsay, 91–123.

    Google Scholar 

  • DiPaola, R., Bazin, J. P., Aubry, F., Aurengo, A., Cavailloles, F., Herry, J. Y. and Kahn, E. (1982). Handling of dynamic sequences in nuclear medicine, IEEE Trans. Nucl. Sci., NS-29, 1310–1321.

    Google Scholar 

  • DiPaola, R., Boudet, F., Bazin, J. P., Aubert, B. and Ricard, M. (1985). Factor analysis in routine quality control of gamma camera energy correction, Poster Presentation, European Nuclear Medicine Congress, London.

    Google Scholar 

  • Eckart, C. and Young, G. (1936). The approximation of one matrix by another of lower rank, Psychometrika, 1, 211–218.

    Article  MATH  Google Scholar 

  • Goris, M. L. (1982). Functional or parametric images, J. Nucl. Med., 23, 360–362.

    Google Scholar 

  • Gremillet, E., Herrmann, T., Essabah, H., Rusch, P., Champailler, A. and Healy, J. C. (1986). New non-invasive method for assessment of 99mTc-RBC cerebral transit: a quantitative use of factorial analysis, Nuklearmedizin, Suppl. 22, 21–22.

    Google Scholar 

  • Harman, H. H. (1960). Modern Factor Analysis, University of Chicago Press, Chicago.

    MATH  Google Scholar 

  • Herry, J. Y., Bazin, J. P., Bourguet. P., DiPaola, M. and DiPaola, R. (1982). Factor analysis of dynamic structures. Application to kinetics of hepatobiliary traces, in: Nuclear Medicine and Biology, C. Raynaud, ed., Pergamon Press, Paris, 2240–2243.

    Google Scholar 

  • Horst, P. (1965). Factor Analysis of Data Matrices, Holt, Rinehart and Winston, New York.

    Google Scholar 

  • Houston, A. S. (1984). The effect of apex-finding errors on factor images obtained from factor analysis and oblique transformation, Phys. Med. Biol., 29, 1109–1116.

    Google Scholar 

  • Houston, A. S. (1986). The use of set theory and cluster analysis to investigate the constraint problem in factor analysis in dynamic structures, in: Information Processing in Medical Imaging, S. L. Bacharach, ed., Martinus Nijhoff Publishers, Dordrecht, 177–192.

    Google Scholar 

  • Houston, A. S., MacLeod, M. A. and Sampson, F. D. (1979). Principal component analysis as an aid to classification of renal dynamic studies, Eur. J. Nucl. Med., 4, 295–299.

    Google Scholar 

  • Johnson, R. M. (1963). On a theorem stated by Eckart and Young, Psychometrika, 28, 259–263.

    Article  MathSciNet  MATH  Google Scholar 

  • Jöreskog, K. G. (1963). Statistical Estimation in Factor Analysis, Almquist and Wiksell, Uppsala.

    MATH  Google Scholar 

  • Jöreskog, K. G., Klovan, J. E. and Reyment, R. A. (1976). Geological Factor Analysis, Elsevier Scientific Publishing Company, Amsterdam.

    Google Scholar 

  • Kaiser, H. F. (1958). The varimax criterion for analytic rotation in factor analysis, Psychometrika, 23, 187–200.

    Article  MATH  Google Scholar 

  • Kârnÿ, M. (1982). Recursive parameter estimation of regression model when the interval of possible values is given, Kybernetika (Prague), 18, 37–49.

    MathSciNet  Google Scholar 

  • Nijran, K. S. and Barber, D. C. (1985). Towards automatic analysis of dynamic radionuclide studies using principal component factor analysis, Phys. Med. Biol., 30, 1315–1325.

    Google Scholar 

  • Nijran, K. S. and Barber, D. C. (1986). Factor analysis of dynamic function studies using a priori physiological information, Phys. Med. Biol., 31, 1107–1117.

    Google Scholar 

  • Oppenheim, B. E. and Appledorn, C. R. (1979). Functional renal imaging using factor analysis, in: Information Processing in Medical Imaging, R. DiPaola and E. Kahn, eds., INSERM 88, Paris, 321–334.

    Google Scholar 

  • Pavel, D. G. and Briandet, P. A. (1983). Quo vadis phase analysis, Clin. Nucl. Med., 8, 564–575.

    Google Scholar 

  • Pavel, D. G., Briandet, P. A., Fang, R. B., Zolnierczyk, K. and Sychra, J. (1984). The normal heart: patterns for various functional images obtained from radionuclide gated equilibrium studies, in: Informatioín Processing in Medical Imaging, F. Deconinck, ed., Martinus Nijhoff Publishers, Boston, 250–265.

    Google Scholar 

  • Pavel, D. G., Sychra, J., Olea, E., Kahn, C., Virupannavar, S., Zolnierczyk, K. and Shanes, J. (1986). Factor analysis: its place in the evaluation of ventricular regional wall motion abnormalities, in: Information Processing in Medical Imaging, S. L. Bacharach, ed., Martinus Nijhoff Publishers, Dordrecht, 193–206.

    Google Scholar 

  • Sâmal, M., Súrovâ, H., Maríkovâ, E., Kârnÿ, M. and Dienstbier, Z. ( 1986 a). Improved precision, quantitative expression and enhancement of physiological factors in factor analysis of dynamic studies, Nuklearmedizin, Suppl. 22, 649–650.

    Google Scholar 

  • Sâmal, M., Súrovâ, H., Kârnÿ, M., Maríkovâ, E., Michalovâ, K. and Dienstbier, Z. ( 1986 b). Enhancement of physiological factors in factor analysis of dynamic studies, Eur. J. Nucl. Med., 12, 280–283.

    Google Scholar 

  • Sâmal, M., Kârn, M., Súrovâ, H., Maríkovâ, E., and Dienstbier, Z. (1987). Rotation to simple structure in factor analysis of dynamic radionuclide studies, Phys. Med. Biol., 32, 371–382.

    Google Scholar 

  • Schmidlin, P. (1979). Quantitative evaluation and imaging of functions using pattern recognition methods, Phys. Med. Biol., 24, 385–395.

    Google Scholar 

  • Schmidlin, P. and Rösel, F. (1975). Application of factor analysis for scintigraphic picture processing, in: Information Processing in Scintigraphy, C. Raynaud and A. Todd-Pokropek, eds., Proceedings of the IVth International Conference, Orsay, 80–90.

    Google Scholar 

  • Soussaline, F., Todd-Pokropek, A. E., DiPaola, R. and Bazin, J. P. (1975). Techniques for combining isotopic images obtained at different energies, in: Information Processing in Scintigraphy, C. Raynaud and A. Todd-Pokropek, eds., Proceedings of the IVth International Conference, Orsay, 17–42.

    Google Scholar 

  • Thurstone, L. L. (1947). Multiple Factor Analysis, University of Chicago Press, Chicago.

    MATH  Google Scholar 

  • Uberla, K. (1971). Faktorenanalyse (in German), Springer Verlag, Berlin. Villanueva-Meyer, J., Philippe, L., Cordero, S., Marcus, C. S. and Mana, I. (1986). Use of factor analysis in the evaluation of left to right cardiac shunts. J. Nucl. Med., 27, 1442–1448.

    Google Scholar 

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Šámal, M., Sůrová, H., Kárný, M., Maříková, E., Pěnička, P., Dienstbier, Z. (1988). The Reality and Meaning of Physiological Factors. In: de Graaf, C.N., Viergever, M.A. (eds) Information Processing in Medical Imaging. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7263-3_33

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  • DOI: https://doi.org/10.1007/978-1-4615-7263-3_33

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-7265-7

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