Abstract
The clinical efficacy of various drugs used in the treatment of affective disorders has been well established during the past decade.(1–7) The biological actions of these drugs, including their neurochemical and behavioral effects, have been fairly extensively investigated(3–18) and aspects of this literature have been reviewed recently. This chapter will focus primarily on the effects of these drugs on the physiology and metabolism of the biogenic amines in the nervous system. The effects of these drugs on behavior in animals, as well as in man, will also be reviewed, since the correlation of alterations in behavior with neurochemical changes has been of considerable interest in this field of research.
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Schildkraut, J.J., Gershon, E.S. (1971). Antidepressants and Related Drugs. In: Lajtha, A. (eds) Alterations of Chemical Equilibrium in the Nervous System. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7175-9_14
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