Abstract
One of the major achievements of genetics has been to work out arrangements of genes relative to each other. Initial work showed free segregation of genes, as already described, which is expected when two loci are on non-homologous chromosomes. However, when the two loci are close together on homologous chromosomes they tend to segregate together at meiosis, i.e. they are said to be linked. The frequency with which re-assortment or recombination occurs is a measure of the distance between the two loci, and this can be used to construct a genetic map.
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Bainbridge, B.W. (1987). Construction of Genetic Maps and the Genetic Code. In: Genetics of Microbes. Tertiary Level Biology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7093-6_2
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DOI: https://doi.org/10.1007/978-1-4615-7093-6_2
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