Skip to main content

Transfer of Beta-Lactam Antibiotic Resistance in Bacteroides

  • Chapter
Genetics and Molecular Biology of Anaerobic Bacteria

Part of the book series: Brock/Springer Series in Contemporary Bioscience ((BROCK/SPRINGER))

  • 578 Accesses

Abstract

It is well known that Bacteroides fragilisand related species produce several kinds of beta-lactamases such as oxyiminocephalosporinase, penicillinase, and metallo-beta-lactamase, with some strains showing a particularly high resistance to beta-lactam antibiotics. Until now, there have only been scattered reports about the transfer of beta-lactam resistance among Bacteroides. Beta-lactam resistance in Bacteroidesseemed to be mobilized by a group of tetracycline resistance transfer elements as discussed in Chapter 35. However, we have found that B. fragiliscould transfer beta-lactam resistances in the absence of such transfer elements.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Bandoh, K., Y. Muto, K. Watanabe, K. Naoki, and K. Ueno. 1991. Biochemical properties and purification of metallo-betα-lactamase from Bac-teroides fragilis. Antimicrob. Agents Chemother. 35:371–372.

    PubMed  CAS  Google Scholar 

  • Bunai, M., K. Watanabe, Y. Hioki, M. Miyauchi, and K. Ueno. 1987. Transferable resistance to cefoxitin in the Bacteroides fragilisgroup. Acta Sch. Med. Univ. Gifu 35:414–425.

    Google Scholar 

  • Butler, T., F.P. Tally, S.L. Gorbach, and M.H. Malamy. 1980. Transferable ampicillin resistance in Bacteroides fragilis. Clin. Res. 28:365 (abstr.).

    Google Scholar 

  • Cuchural, G.J., Jr., M.H. Malamy, and F.P. Tally. 1986a. Beta-lactamase mediated imipenem resistance in Bacteroides fragilis. Antimicrob. Agents Chemother. 30:645–648.

    PubMed  CAS  Google Scholar 

  • Cuchural, G.J., Jr., F.P. Tally, J.R. Storey, and M.H. Malamy. 1986b. Transfer of beta-lactamase-associated cefoxitin resistance in Bacteroides fragilis. Antimicrob. Agents Chemother. 29:918–920.

    PubMed  CAS  Google Scholar 

  • Guiney, D.G. and K. Bouic. 1990. Detection of conjugal transfer systems in oral, black-pigmented Bacteroidesspp. J. Bacteriol. 172:495–497.

    PubMed  CAS  Google Scholar 

  • Morita, K., A. Miyano, M. Hayashi, and K. Shiga. 1986. Study on molecular genetics of betα-lactam antibiotics resistance plasmid pBFSKl from Bacteroides fragilis. J. Kyorin Med. Soc. 17:531–537.

    Google Scholar 

  • Sato, K., Y. Matsuura, M. Inoue, and S. Mitsuhashi. 1982. Properties of a new penicillinase type produced by Bacteroides fragilis. Antimicrob. Agents Chemother. 22:579–584.

    PubMed  CAS  Google Scholar 

  • Thompson, J.S. and M.H. Malamy. 1990. Sequencing the gene for an imipenem-cefoxitin-hydrolyzing enzyme (cfiA) from Bacteroides fragilisTAL-2480 reveals strong similarity between cfiA and Bacillus cereusbeta-lactamase II. J. Bacteriol. 172:2584–2593.

    PubMed  CAS  Google Scholar 

  • Varel, V.H. and M.P. Bryant. 1974. Nutritional features of Bacteroides fragilis. Appl. Microbiol. 28:251–257.

    PubMed  CAS  Google Scholar 

  • Yamaoka, K., K. Watanabe, Y. Muto, N. Katoh, K. Ueno, and F.P. Tally. 1990. R-plasmid mediated transfer of beta-lactam resistance in Bacteroides fragilis. J. Antibiot. (Tokyo) 43:1302–1306.

    Article  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1993 Springer-Verlag New York, Inc.

About this chapter

Cite this chapter

Watanabe, K., Ueno, K. (1993). Transfer of Beta-Lactam Antibiotic Resistance in Bacteroides . In: Sebald, M. (eds) Genetics and Molecular Biology of Anaerobic Bacteria. Brock/Springer Series in Contemporary Bioscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-7087-5_36

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-7087-5_36

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4615-7089-9

  • Online ISBN: 978-1-4615-7087-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics