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Dietary Fiber, Bile Acids, and Intestinal Morphology

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Dietary Fiber in Health and Disease

Abstract

The rates of occurrence and mortality from colorectal cancer have been positively correlated with total fat intake in several populations (Carroll and Khor, 1975; Correa and Haenszel, 1978; Wynder, 1979). The possible relationships between fat ingestion and the subsequent steps in lipid metabolism have been explored in studies aimed at determining the link between bowel cancer risk, dietary fats, products of fat metabolism, and their appearance in the stool composition.Of the populations with higher incidences of bowel cancer there is also evidence of higher fecal steroids, bile acids, and 7-dehydroxylase activity (Hill et al., 1975, Reddy et al.,1975a) compared to control studies. Subjects with higher levels of fat consumption also demonstrate a high fecal concentration of important lipid metabolites (Reddy et al., 1976).

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Author information

Authors and Affiliations

  1. Department of Physiology, The George Washington University, School of Medicine and Health Sciences, Washington, D.C., 20037, USA

    Marie M. Cassidy

  2. Department of Anatomy, The George Washington University, School of Medicine and Health Sciences, Washington, D.C., 20037, USA

    Fred G. Lightfoot

  3. Department of Biochemistry, The George Washington University, School of Medicine and Health Sciences, Washington, D.C., 20037, USA

    George V. Vahouny

Authors
  1. Marie M. Cassidy
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  2. Fred G. Lightfoot
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  3. George V. Vahouny
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Editor information

Editors and Affiliations

  1. Department of Biochemistry, School of Medicine and Health Sciences, The George Washington University Medical Center, 20037, Washington, D.C., USA

    George V. Vahouny

  2. The Wistar Institute of Anatomy and Biology, 19104, Philadelphia, Pennsylvania, USA

    David Kritchevsky

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© 1982 Plenum Press, New York

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Cassidy, M.M., Lightfoot, F.G., Vahouny, G.V. (1982). Dietary Fiber, Bile Acids, and Intestinal Morphology. In: Vahouny, G.V., Kritchevsky, D. (eds) Dietary Fiber in Health and Disease. GWUMC Department of Biochemistry Annual Spring Symposia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6850-6_22

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  • DOI: https://doi.org/10.1007/978-1-4615-6850-6_22

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-6852-0

  • Online ISBN: 978-1-4615-6850-6

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