Abstract
Any analysis of cardiac relaxation requires an understanding of the role of the sarcoplasmic reticulum (SR) in removing activator Ca2+ from the cytosol at the end of systole. The precise relationship between Ca2+ uptake into this intracellular membrane system and the changes in muscle length and tension that occur during diastole remains incompletely understood, but it is generally accepted that relaxation begins when cytosolic Ca2+ is reduced by the calcium pump of the SR.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Tada M, Yamamoto T, Tonomura Y (1978). Molecular mechanism of active calcium transport by sarcoplasmic reticulum. Physiol Rev 58: 1–79.
Martin DW, Tanford C (1981). Phosphorylation of calcium adenosine triphosphatase by inorganic phosphate: van’t Hoff analysis of enthalpy changes. Biochem 20: 4597–4602.
Inesi G (1981). The sarcoplasmic reticulum of skeletal and cardiac muscle. In Dowben RM, Shay JW (eds): Cell and Muscle Motility. Plenum, New York: 63–97.
Ikemoto N (1982). Structure and function of the calcium pump protein of sarcoplasmic reticulum. Annu Rev Physiol 44: 297–317.
Shigekawa M, Wakabayashi S, Nakamura H (1983). Reaction mechanism of Ca2+-dependent adenosine triphosphatase of sarcoplasmic reticulum. J Biol Chem 258: 8698–8707.
Tada M, Katz AM (1982). Phosphorylation of the sarcoplasmic reticulum and sarcolemma: Annu Rev Physiol 44: 401–423.
Katz AM, Takenaka H, Watras J (1986). The sarcoplasmic reticulum. In Fozzard H, et al (eds): The Heart and Cardiovascular System. New York: Raven Press.
Endo M (1977). Calcium release from the sarcoplasmic reticulum. Physiol Rev 57: 7 1108.
Fabiato A (1983). Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum. Am J Physiol 245: C1 - C14.
Somlyo AV,•Gonzalez-Serratos H, McClellan G, Somlyo AP (1981). Calcium release and ionic changes in the sarcoplasmic reticulum of tetanized muscle: An electron-probe study. J Cell Biol 90: 577–594.
Martonosi A (1984). Mechanisms of Ca2+ release from sarcoplasmic reticulum of skeletal muscle. Physiol Rev 64: 1240–1320.
Katz AM, Repke DI, Fudyma G, Shigekawa M (1977). Control of calcium efflux from sarcoplasmic reticulum vesicles by external calcium. J Biol Chem 252: 4210–4212.
Fleischer S, Ogunbunmi EM, Dixon MC, Fleer EAM (1985). Localization of Ca2+ release channels with ryanodine in junctional terminal cisternae of sarcoplasmic reticulum of fast skeletal muscle. Proc Acad Sci USA 82: 72567259.
Tsien RW (1983). Calcium channels in excitable cell membranes. Annu Rev Physiol 45: 341–358.
Shigekawa M, Finegan J-AM, Katz AM (1976). Calcium transport ATPase of canine cardiac. sarcoplasmic reticulum: A comparison with that of rabbit fast skeletal muscle sarcoplasmic reticulum. J Biol Chem 251: 68946900.
Smith V-E, Weisfeldt ML, Katz AM (1986) Relaxation and diastolic properties of the heart. In Fozzard H, et al (eds): The Heart and Cardiovascular System. New York: Raven Press.
Katz AM, Messineo FC, Nash-Adler P (1986). Effects of amphiphilic substances on sarcoplasmic reticulum function. In Entman ML, Van Winkle WB: Sarcoplasmic Reticulum in Muscle Physiology, vol II. Boca Raton, FL: CRC Press, pp 123–139.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1987 Martinus Nijhoff Publishing
About this chapter
Cite this chapter
Katz, A.M. (1987). Sarcoplasmic Reticular Control of Cardiac Contraction and Relaxation. In: Grossman, W., Lorell, B.H. (eds) Diastolic Relaxation of the Heart. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6832-2_2
Download citation
DOI: https://doi.org/10.1007/978-1-4615-6832-2_2
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4615-6834-6
Online ISBN: 978-1-4615-6832-2
eBook Packages: Springer Book Archive