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Diastolic Relaxation of the Heart pp 255–279Cite as

Ejection, Filling and Diastasis during Transluminal Occlusion in Man: Consideration on Global and Regional Left Ventricular Function

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Abstract

An extensive literature exists that describes the acute changes in hemodynamics and left ventricular function following coronary occlusion in animals [1–4]. Much less, however, is known in humans. Extrapolating results from animals to humans is potentially difficult, because in humans preexisting atherosclerotic coronary disease and a unique distribution of collateral circulation [5–7] may influence the findings. Until recently, measurement of left ventricular geometry and hemodynamics early after an abrupt occlusion of a major coronary artery has not been feasible in humans. Percutaneous transluminal coronary angioplasty (PTCA), however, now provides a unique opportunity to study the time course of these variables during the transient interruption of coronary flow in the balloon occlusion sequence in patients with single-vessel disease and without angiographically demonstrable collateral circulation [8–10].

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Authors
  1. Patrick W. Serruys
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  2. William Wijns
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  3. Federico Piscione
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  4. Pim de Feyter
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  5. Paul G. Hugenholtz
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Editor information

Editors and Affiliations

  1. Harvard Medical School, Cardiovascular Division, Beth Israel Hospital, Boston, Massachusetts, USA

    William Grossman M.D. (Herman Dana Professor of Medicine, Chief) (Herman Dana Professor of Medicine, Chief)

  2. Harvard Medical School, Hemodynamic Research Laboratory, Beth Israel Hospital, Boston, Massachusetts, USA

    Beverly H. Lorell M.D. (Assistant Professor of Medicine, Co-Director) (Assistant Professor of Medicine, Co-Director)

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© 1987 Martinus Nijhoff Publishing

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Serruys, P.W., Wijns, W., Piscione, F., de Feyter, P., Hugenholtz, P.G. (1987). Ejection, Filling and Diastasis during Transluminal Occlusion in Man: Consideration on Global and Regional Left Ventricular Function. In: Grossman, W., Lorell, B.H. (eds) Diastolic Relaxation of the Heart. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6832-2_25

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  • DOI: https://doi.org/10.1007/978-1-4615-6832-2_25

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-6834-6

  • Online ISBN: 978-1-4615-6832-2

  • eBook Packages: Springer Book Archive

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