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Sarcoplasmic Reticular Control of Cardiac Contraction and Relaxation

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Diastolic Relaxation of the Heart

Abstract

Any analysis of cardiac relaxation requires an understanding of the role of the sarcoplasmic reticulum (SR) in removing activator Ca2+ from the cytosol at the end of systole. The precise relationship between Ca2+ uptake into this intracellular membrane system and the changes in muscle length and tension that occur during diastole remains incompletely understood, but it is generally accepted that relaxation begins when cytosolic Ca2+ is reduced by the calcium pump of the SR.

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© 1987 Martinus Nijhoff Publishing

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Katz, A.M. (1987). Sarcoplasmic Reticular Control of Cardiac Contraction and Relaxation. In: Grossman, W., Lorell, B.H. (eds) Diastolic Relaxation of the Heart. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6832-2_2

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  • DOI: https://doi.org/10.1007/978-1-4615-6832-2_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-6834-6

  • Online ISBN: 978-1-4615-6832-2

  • eBook Packages: Springer Book Archive

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