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Renal Transplantation

  • Chapter
Contemporary Nephrology

Abstract

Without question, the most important recent advance in clinical renal transplantation has been a dramatic reduction in patient mortality, especially mortality secondary to infectious disease. Our unit (Tilney et al., 1978) and others have noted this trend and have offered similar suggestions for reducing immunosuppressive therapy. We reported that recent modifications and refinements in the management of renal-transplant recipients have diminished the mortality rate to 2 and 5% at 1 year for patients receiving kidneys from related and cadaveric sources, respectively. This patient population included 15% high-risk patients (juvenile diabetics or those over 55 years old). Subsequent to this report, further refinements in cross-matching techniques and a more liberal blood-transfusion policy have increased cadaver-graft survival to 65%. The modifications are listed in Table I.

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Author information

Authors and Affiliations

  1. Peter Bent Brigham Hospital Division, Affiliated Hospital Center, Harvard Medical School, Boston, Massachusetts, 02115, USA

    Terry B. Strom

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  1. Terry B. Strom
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Editors and Affiliations

  1. Washington University School of Medicine, St. Louis, Missouri, USA

    Saulo Klahr M.D.

  2. University of Southern California School of Medicine, Los Angeles, California, USA

    Shaul G. Massry M.D.

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© 1981 Springer Science+Business Media New York

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Strom, T.B. (1981). Renal Transplantation. In: Klahr, S., Massry, S.G. (eds) Contemporary Nephrology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6719-6_14

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  • DOI: https://doi.org/10.1007/978-1-4615-6719-6_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-6721-9

  • Online ISBN: 978-1-4615-6719-6

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