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Membrane Transport

  • Chapter
Contemporary Nephrology

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Abstract

To many who deal with the physiology and pathology of the kidney, the study of membrane transport mechanisms may appear to be a rather esoteric deviation from the processes of primary interest, i.e., normal or deranged control of body homeostasis. However, the kidney, and also the alimentary canal, are preeminent examples of “transport organs.” Certainly all living cells exhibit continuous fluxes of substances across their organelle and plasma membranes that maintain steady-state internal environments different from their surrounding environment. But the kidney and the alimentary canal exhibit net transepithelial transport of solutes and water. In the case of the kidney, these processes are finely regulated so that they result in a final excretion of solutes and water that balances the daily inputs from food intake and metabolism. At every level of organization of the kidney, net transport processes can be observed to underlie function.

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Authors and Affiliations

  1. Nephrology Research and Training Center, Departments of Physiology and Biophysics, and Department of Medicine, University of Alabama in Birmingham, Birmingham, Alabama, 35294, USA

    James A. Schafer

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  1. Washington University School of Medicine, St. Louis, Missouri, USA

    Saulo Klahr M.D.

  2. University of Southern California School of Medicine, Los Angeles, California, USA

    Shaul G. Massry M.D.

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Schafer, J.A. (1981). Membrane Transport. In: Klahr, S., Massry, S.G. (eds) Contemporary Nephrology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6719-6_1

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