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Obstructive Sleep Apnea

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Part of the book series: Contemporary Internal Medicine ((COIM,volume 1))

Abstract

This 62-year-old white female had been in good health for most of her life, with the exception of a history of congenital heart disease. In 1975, at the age of 55, she was found to have an ostium primum atrial septal defect, as well as a cleft mitral valve which was mildly regurgitant. Second-degree AV block was present. In late 1975 she underwent surgical repair of the atrial septal defect and had a permanent pacemaker installed. She felt reasonably well until 1980, two years prior to admission, when she had the onset of palpitations during sleep. She would awaken with a sensation of forceful pounding in the chest. Recurrent nightmares became a problem. There was a thirty-year history of snoring, although her family had not noticed any periods of apnea, choking, or gasping for air. She did state that she often abruptly awakened from sleep, although she was not aware of the reason. In addition, the patient complained of severe headaches which usually occurred in the morning upon arising from bed. The patient stated that she was always able to fall asleep easily. However, excessive daytime sleepiness or falling asleep at inappropriate times had not occurred. There were no other significant complaints.

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References

  1. Strohl KP, Chemiack NS, Gothe B. Physiologic basis of therapy for sleep apnea. Am. Rev. Resp Dis. 1986;134:791–802.

    PubMed  CAS  Google Scholar 

  2. Orr WC. Sleep related breathing disorders: An update. Chest. 1983; 84:475–80.

    Article  PubMed  CAS  Google Scholar 

  3. Ingbar DH, Gee JBL. Pathophysiology and treatment of sleep apnea. Ann Rev Med. 1985; 36:369–95.

    Article  PubMed  CAS  Google Scholar 

  4. Kales A., Vela-Bueno A, Kales JD. Sleep disorders: Sleep apnea and narcolepsy. Ann. Intern Med. 1987;106:434–43.

    PubMed  CAS  Google Scholar 

  5. Guilleminault C. Obstructive sleep apnea: The clinical syndrome and historical perspective. Med Clin No Am. 1985;69:1187–1203.

    CAS  Google Scholar 

  6. Weil JV, Cherniack NS, Dempsey JA, et al. Respiratory disorders of sleep: Pathophysiology, clinical implications, and therapeutic approaches. Am Rev Resp Dis. 1987;136:755–61.

    Article  PubMed  CAS  Google Scholar 

  7. Orr WC. Utilization of polysomnography in the assessment of sleep disorders. Med Clin No Am. 1985;69:1153–67.

    CAS  Google Scholar 

  8. Kales A, Soldatos CR, Kales JD. Taking a sleep history. Am Fam Physician. 1980;22:101–7.

    PubMed  CAS  Google Scholar 

  9. Kales A. Caldwell AB, Cadieux RJ, Vela-Bueno A, Ruch LG, Mayes SD. Severe obstructive sleep apnea.II. Associated psychopathology and psychosocial consequences. J Chron Dis. 1985;38:427–34.

    Article  PubMed  CAS  Google Scholar 

  10. Haponik EF, Bleeker ER, Allen RP, Smith PL, Kaplan J. Abnormal inspiratory flow volume curves in patients with sleep-disordered breathing. Am Rev Resp Dis. 1981;124:571–4.

    PubMed  CAS  Google Scholar 

  11. Shore ET, Millman RP. Abnormalities in the flow volume loop in obstructive sleep apnoea sitting and supine. Thorax. 1984;39:775–9.

    Article  PubMed  CAS  Google Scholar 

  12. Haponik EF, Smith PL, Bohlman ME, Allen RP, Goldman SM, Bleecker ER Computerized tomography in obstructive sleep apnea: Correlation of airway size with physiology during sleep and wakefulness. Am Rev Resp Dis. 1983;127:221–6.

    PubMed  CAS  Google Scholar 

  13. Lavie P. Incidence of sleep apnea in a presumably healthy working population: A significant relationship with excessive daytime sleepiness. Sleep. 1983;6:312–8.

    PubMed  CAS  Google Scholar 

  14. Block AJ, Boysen PG, Wynne JW, Hunt LA. Sleep apnea, hypoapnea, and oxygen desaturation in normal subjects. N Engl J Med. 1979;300:513–7.

    Article  PubMed  CAS  Google Scholar 

  15. Lugaresi E, Coccagna G, Mantovani M. Hypersomnia with periodic apneas. In: Weitzman ED, ed. Advances in Sleep Research. Vol 4. New York: Spectrum Publications, 1978.

    Google Scholar 

  16. Osler W. The Principles and Practice of Medicine. New York: Appleton, 1918.

    Google Scholar 

  17. Burwell C, Robin E, Whaley R, Bikelman A. Extreme obesity associated with alveolar hypoventilation: A pickwickian syndrome. Am J Med. 1956;21:811.

    Article  PubMed  Google Scholar 

  18. Block AJ, Faulkner JA, Hughes RL, Remitters JE, Thach B. Factors influencing upper airway closure. Chest. 1984;86:114–22.

    Article  PubMed  CAS  Google Scholar 

  19. Bradley TD, Philiipson EA. Pathogenesis and pathophysiology of the obstructive sleep apnea syndrome. Med Clin No Am. 1985;69:1169–85.

    CAS  Google Scholar 

  20. Sullivan CE, Issa FG, Berthon-Jones M, Saunders NA. Pathophysiology of sleep apnea. In: Saunders NA, Sullivan CE, eds. Sleep and Breathing. New York: Marcel Dekker, 1984;299–364.

    Google Scholar 

  21. Brown IG, Bradley TD, Philiipson EA, Zamel N, Hoffstein V. Pharyngeal compliance in snoring subjects with and without obstructive sleep apnea. Am. Rev Resp Dis. 1985;132:211–5.

    PubMed  CAS  Google Scholar 

  22. Lombard RM, Zwillich CW. Medical therapy of obstructive sleep apnea. Med Clin No Am. 1985;69:1317–35.

    Google Scholar 

  23. Harmon EM, Wynne JW, Block AJ. The effect of weight loss on sleep disordered breathing and oxygen desaturation in normal man. Chest. 1982;82:291–94.

    Article  Google Scholar 

  24. Sullivan CE, Berthon-Jones M, Issa FQ, Eves L. Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares. Lancet. 1981;1:862–5.

    Article  PubMed  CAS  Google Scholar 

  25. Sullivan CE, Issa FG, Berthon-Jones M, McCauley VB, Costas LJV. Home treatment of obstructive sleep apnea with continuous positive airway pressure applied through a nose mask. Bull Eur Physiopath Respir. 1984;20:49–54.

    CAS  Google Scholar 

  26. Remmers JE, Sterling JA. Thorarinsson B, Kuna ST. Nasal airway positive pressure in patients with occlusive sleep apnea: Methods and feasibility. Am Rev Resp Dis. 1984;130:1152–5.

    PubMed  CAS  Google Scholar 

  27. Saunders MH, Gruendl CA, Rogers RM. Patient compliance with nasal CPAP therapy for sleep apnea. Chest. 1986;90:330–3.

    Article  Google Scholar 

  28. Thawley SE. Surgical treatment of obstructive sleep apnea. Med. Clin. No Am. 1985;69:1337–58.

    CAS  Google Scholar 

  29. Guilleminault C, Simmons FB, Motta J, Cumminsky J, Rosekind M, Schroeder JS, Dement WC. Obstructive sleep apnea syndrome and tracheostomy: Long term follow-up experience. Arch Intern Med. 1981;141:985–8.

    Article  PubMed  CAS  Google Scholar 

  30. Orsini MA, Conner GH, Cadieux RJ, Kales A. Clinical experience with the silicone tracheal cannula in obstructive sleep apnea. Otolaryngol Head Neck Surg. 1984;92:132–5.

    PubMed  CAS  Google Scholar 

  31. Fujita S., Conway WA, Zorich F., Roth T. Surgical correction of anatomic abnormalities in obstructive sleep apnea: uvulopalatopharyngoplasty. Otolaryngol Head Neck Surg. 1981;89:923–34.

    PubMed  CAS  Google Scholar 

  32. Katsantonis GP, Walsh JK, Schweitzer PK, Friedman WH. Further evaluation of uvulopalatopharyngoplasty in the treatment of obstructive sleep apnea syndrome. Otolaryngol Head Neck Surg. 1985;93:244–50.

    PubMed  CAS  Google Scholar 

  33. Rajagopal KR, Abbrecht PH, Jabbari B. Effects of medroxyprogesterone acetate in obstructive sleep apnea. Chest. 1986;90:815–21.

    Article  PubMed  CAS  Google Scholar 

  34. Gothe B, Strohl KP, Levin S, Cherniack NS. Nicotine: A different approach to treatment of obstructive sleep apnea. Chest 1985; 87:11–7.

    Article  PubMed  CAS  Google Scholar 

  35. Brownell LG, West P, Sweatman P, Acres JC, Kryger M. Protriptyline in obstructive sleep apnea: A double-blind trial. N Engl J Med. 1982;307:1038–42.

    Article  Google Scholar 

  36. Bonora M, St. John WM, Bledsoe TA. Differential evaluation by protriptyline and depression by diazepam of upper airway respiratory motor activity. Am Rev Resp Dis. 1985;131:41–5.

    PubMed  CAS  Google Scholar 

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© 1988 Plenum Publishing Corporation

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Pacht, E.R. (1988). Obstructive Sleep Apnea. In: Bowen, J., Mazzaferri, E.L. (eds) Contemporary Internal Medicine. Contemporary Internal Medicine, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6713-4_5

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  • DOI: https://doi.org/10.1007/978-1-4615-6713-4_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-6715-8

  • Online ISBN: 978-1-4615-6713-4

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