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Infections Complicating Congenital Immunodeficiency Syndromes

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Clinical Approach to Infection in the Compromised Host

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Abstract

Nothing is more challenging to the physician than the management of a serious infection in an immunocompromised host. Under such circumstances, the clinician must bring to bear all of his knowledge of microbiology and antimicrobial therapy, but in addition, he must have a firm understanding of the host defense abnormality underlying that individual patient’s disease. As indicated by Stollerman in a recent review,1 we can no longer have a primarily parasite-oriented approach to infectious diseases but must include host factors in the data on which we make potentially life-saving decisions.

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  1. Departments of Pediatrics and Pathology, Division of Clinical Immunology and Allergy, University of Utah School of Medicine, Salt Lake City, Utah, 84132, USA

    Harry R. Hill

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  1. Infectious Disease and Transplantation Units, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, 02114, Boston, Massachusetts, USA

    Robert H. Rubin M.D.

  2. Kuzell Institute for Arthritis and Infectious Diseases, Division of Infectious Diseases, Pacific Presbyterian Medical Center, 94115, San Francisco, California, USA

    Lowell S. Young M.D.

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Hill, H.R. (1988). Infections Complicating Congenital Immunodeficiency Syndromes. In: Rubin, R.H., Young, L.S. (eds) Clinical Approach to Infection in the Compromised Host. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6645-8_16

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