Abstract
There is perhaps more information available today regarding the properties of hippocampal pyramidal cells than of any other CNS cell type except the spinal cord motoneuron. The hippocampus, with the associated dentate granule cell region, has been studied intensively with electrophysiological techniques. The reasons for such interest and study are several, ranging from the technical accessibility of hippocampal neurons to their hypothesized role in learning and memory (see Isaacson and Pribram, 1975; Swanson et al. 1982; Seifert, 1983).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Abraham, W. C., 1982, Failure of cable theory to explain differences between medial and lateral perforant path evoked potentials, Proc. Univ. Otago Med. Sch. 60:23–24
Adams, P. R., and Halliwell, J. V., 1982, A hyperpolarization-induced inward current in guinea pig hippocampal neurones, J. Physiol. (London) 324:62P–63P
Aldenhoff, J. B., Gruol, D. L., and Siggins, G. R., 1982, Corticotropin releasing factor (CRF) depolarizes and excites pyramidal neurons of the hippocampal slice preparation, Soc. Neurosci. Abstr. 8:983.
Alger, B. E., 1984, Characteristics of a slow hyperpolarizing synaptic potential in rat hippocampal neurons, J. Neurophysiol. 52:892–910.
Alger, B. E., and Nicoll, R. A., 1979, GABA-mediated biphasic inhibitory responses in hippocampus, Nature 281:315–317.
Alger, B. E., and Nicoll, R. A., 1980a, Epileptiform burst hyperpolarization: Calcium-dependent potassium potential in hippocampal CA1 pyramidal cells, Science 210:1122–1124.
Alger, B. E., and Nicoll, R. A., 1980b, Spontaneous inhibitory post-synaptic potentials in hippocampus: Mechanism for tonic inhibition, Brain Res. 200:195–200.
Alger, B. E., and Nicoll, R. A., 1982a, Feed-forward dendritic inhibition in rat hippocampal pyramidal cells studied in vitro, J. Physiol. (London) 328:105–123.
Alger, B. E., and Nicoll, R. A., 1982b, Pharmacological evidence for two kinds of GABA receptor on rat hippocampal pyramidal cells studied in vitro, J. Physiol. (London) 328:125–141.
Alger, B. E., and Nicoll, R. A., 1983, Ammonia does not selectively block IPSPs in rat hippocampal pyramidal cells, J. Neurophysiol. 49:1381–1391.
Alger, B. E., and Teyler, T. J., 1976, Long-term and short-term plasticity in CA1, CA3 and dentate regions of the rat hippocampal slice, Brain Res. 110:463–480.
Allen, G. I., Eccles, J., Nicoll, R. A., Oshima, T., and Rubia, F. J., 1977, The ionic mechanisms concerned in generating the i.p.s.ps of hippocampal pyramidal cells, Proc. R. Soc. London Ser. B 198:363–384.
Alvarez-Leefmans, F. J., 1976, Functional synaptic organization of inhibitory pathways in the dentate gyrus of the rabbit, Exp. Brain Res. Suppl. 1:229–234.
Alvarez-Leefmans, F. J., and Gardner-Medwin, A. R., 1975, Influences of the septum on the hippocampal dentate area which are unaccompanied by field potentials, J. Physiol. (London) 24914P–16P
Andersen, P., 1960, Interhippocampal impulses. II. Apical dendritic activation of CA1 neurones, Acta Physiol. Scand. 48:178–208.
Andersen, P., 1975, Organization of hippocampal neurons and their interconnections, in: The Hippocampus (R. L. Isaacson and K. H. Pribram, eds.), Plenum Press, New York, pp. 155–175
Andersen, P., and Lømo, T., 1966, Mode of activation of hippocampal pyramidal cells by excitatory synapses on dendrites, Exp. Brain Res. 2:247–260.
Andersen, P., and Lømo, T., 1967, Control of hippocampal output by afferent volley frequency, Prog. Brain Res. 27:400–412.
Andersen, P., Bruland, H., and Kaada, B. R., 1961a, Activation of the dentate area by septal stimulation, Acta Physiol. Scand. 51:17–28.
Andersen, P., Bruland, H., and Kaada, B. R., 1961b, Activation of the field CA1 of the hippocampus by septal stimulation, Acta Physiol. Scand. 51:29–40.
Andersen, P., Eccles, J. C., and Løyning, Y., 1964a, Location of postsynaptic inhibitory synapses of hippocampal pyramids, J. Neurophysiol. 27:592–607.
Andersen, P., Eccles, J. C., and Løyning, Y., 1964b, Pathway of postsynaptic inhibition in the hippocampus, J. Neurophysiol. 27:608–619.
Andersen, P., Blackstad, T. W., and Lømo, T., 1966a, Location and identification of excitatory synapses on hippocampal pyramidal cells, Exp. Brain Res. 1:236–248.
Andersen, P., Holmqvist, B., and Voorhoeve, P. E., 1966b, Entorhinal activation of dentate granule cells, Acta Physiol. Scand. 66:448–460.
Andersen, P., Holmqvist, B., and Voorhoeve, P. E., 1966c, Excitatory synapses on hippocampal apical dendrites activated by entorhinal stimulation, Acta Physiol. Scand. 66:461–472.
Andersen, P., Gross, G. N., Lømo, T., and Sveen, P., 1969, Participation of inhibitory and excitatory interneurones in the control of hippocampal cortical output, in: The Interneuron (M. A. B. Brazier, ed.), University of California Press, Los Angeles, pp 415–465
Andersen, P., Bliss, T. V. P., and Skrede, K. K., 1971a, Unit analysis of hippocampal population spikes, Exp. Brain Res. 13:208–221.
Andersen, P., Bliss, T. V. P., and Skrede, K. K., 1971b, Lamellar organization of hippocampal excitatory pathways, Exp.Brain Res. 13:222–238.
Andersen, P., Bland, B. H., and Dudar, J. D., 1973, Organization of the hippocampal output, Exp. Brain Res. 17:152–168.
Andersen, P., Sundberg, S. H., Sveen, O., and Wigström, H., 1977, Specific long-lasting potentiation of synaptic transmission in hippocampal slices, Nature 266:736–737.
Andersen, P., Dingledine, R., Gjerstad, L., Langmoen, I. A., and Mosfeldt-Laursen, A., 1980a, Two different responses of hippocampal pyramidal cells to application of gamma-amino butyric acid, J. Physiol. (London) 305:279–296.
Andersen, P., Silfvenius, H., Sundberg, S. H., and Sveen, O., 1980b, A comparison of distal and proximal dendritic synapses on CA1 pyramids in hippocampal slices in vitro, J. Physiol. (London) 307:273–299.
Andersen, P., Sundberg, S. H., Sveen, O., Swann, J. W., and Wigström, H., 1980c, Possible mechanisms for long-lasting potentiation of synaptic transmission in hippocampal slices from guineapigs, J. Physiol. (London) 302:463–482.
Andrew, R. D., Taylor, C. P., Snow, R. W., and Dudek, F. E., 1982, Coupling in rat hippocampal slices: Dye transfer between CA1 pyramidal cells, Brain Res. Bull. 8:211–222.
Assaf, S. Y., Crunelli, V., and Kelly, J. S., 1981, Action of 5-hydroxytryptamine on granule cells in the rat hippocampal slice, J. Physiol. (Paris) 77:377–380.
Azmitia, E. C., and Segal, M., 1978, An autoradiographic analysis of the differential ascending projections of the dorsal and median raphe nuclei in the rat, J. Comp. Neurol. 179:641–668.
Barbaccia, M. L., Brunello, N., Chuang, D.-M., and Costa, E., 1983, Serotonin-elicited amplification of adenylate cyclase activity in hippocampal membranes from adult rat, J. Neurochem. 40:1671–1679.
Barbin, G., Garbarg, M., Schwartz, J.-C., and Storm-MathisenJ., 1976, Histamine synthesizing afferents to the hippocampal region, J. Neurochem. 26:259–263.
Barnes, C. A., and McNaughton, B. L., 1980, Physiological compensation for loss of afferent synapses in rat hippocampal granule cells during senescence, J. Physiol. (London) 309:473–485.
Barnes, C. A., and McNaughton, B. L., 1983, Where is the cognitive map?, Soc. Neurosci. Abstr. 9:649.
Barrett, J. N., and Crill, W. E., 1974, Specific membrane properties of cat motoneurons, J. Physiol. (London) 239:301–324.
Baudry, M., and Lynch, G., 1980, Hypothesis regarding the cellular mechanisms responsible for long-term synaptic potentiation in the hippocampus, Exp. Neurol. 68:202–204.
Baxter, D., and Brown, T. H., 1983, Quantal analysis of long-term synaptic potentiation, Soc. Neurosci. Abstr. 9:103.
Beaumont, K., Chilton, W. S., Yamamura, H. I., and Enna, S. J., 1978, Muscimol binding in rat brain: Association with GABA receptors, Brain Res. 148:153–162.
Benardo, L. S., and Prince, D. A., 1981, Acetylcholine induced modulation of hippocampal pyramidal neurons, Brain Res. 211:227–234.
Benardo, L. S., and Prince, D. A., 1982a, Cholinergic excitation of mammalian hippocampal pyramidal cells, Brain Res. 249:315–331.
Benardo, L. S., and Prince, D. A., 1982b, Ionic mechanisms of cholinergic excitation in mammalian hippocampal pyramidal cells, Brain Res. 249:333–344.
Benardo, L. S., and Prince, D. A., 1982c, Cholinergic pharmacology of mammalian hippocampal pyramidal cells, Neuroscience 7:1703–1712.
Benardo, L. S., and Prince, D. A., 1982d, Dopamine modulates a Ca+ +-activated potassium conductance in mammalian hippocampal pyramidal cells, Nature 297:76–79.
Benardo, L. S., and Prince, D. A., 1982e, Dopamine action on hippocampal pyramidal cells, J. Neurosci. 2:415–423.
Benardo, L. S., Masukawa, L. M., and Prince, D. A., 1982, Electrophysiology of isolated hippocampal pyramidal dendrites, J. Neurosci. 2:1614–1622.
Ben-Ari, Y., Krnjević K., Reiffenstein, R. J., and Reinhardt, W., 1981a, Inhibitory conductance changes and action of gamma-aminobutyrate in rat hippocampus, Neuroscience 6:2445–2463.
Ben-Ari, Y., Krnjević, K., Reinhardt, W., and Ropert, N., 1981b, Intracellular observations on the disinhibitory action of acetylcholine in the hippocampus, Neuroscience 6:2475–2484.
Bennett, J. P., Jr., and Snyder, S. H., 1976, Serotonin and lysergic acid diethylamide binding in rat brain membranes: Relationship to postsynaptic serotonin receptors, Mol. Pharmacol. 12:373–389.
Berger, T., 1983, Long term potentiation of hippocampal synaptic transmission accelerates behavioral learning, Paper presented at the First Biennial Symposium on Neural Mechanisms of Conditioning, Marine Biological Laboratory, Woods Hole, Mass
Berger, T. W., Thompson, and R. F., 1978, Neuronal plasticity in the limbic system during classical conditioning of the rabbit nictitating membrane response. I. The hippocampus, Brain Res. 145:323–346.
Bird, S. J., and Aghajanian, G. K., 1976, The cholinergic pharmacology of hippocampal pyramidal cells: A microiontophoretic study, Neuropharmacology 151:273–282.
Bischoff, S., Scatton, B., and Korf, J., 1979, Dopamine metabolism, spiperone binding and adenylate cyclase activity in the adult rat hippocampus after ingrowth of dopaminergic neurones from embryonic implants, Brain Res. 179:77–84.
Biscoe, T. J., and Straughan, D. W., 1966, Microelectrophoretic studies of neurones in the cat hippocampus, J. Physiol. (London) 183:341–359.
Björklund, A., and Stenevi, U., 1979, Regeneration of monoaminergic and cholinergic neurons in the mammalian central nervous system, Physiol. Rev. 59:62–100.
Blackstad, T. W., 1956, Commissural connections of the hippocampal region in the rat with special reference to their mode of termination, J Comp. Neurol. 105:417–538.
Blackstad, T. W., 1958, On the termination of some afferents to the hippocampus and fascia dentata, Acta Anat. 35:202–214.
Blackstad, T. W., Fuxe, K., and Hökfelt, T., 1967, Noradrenaline nerve terminals in the hippocampal region of the rat and the guinea pig, Z. Zellforsch. 7:463–473.
Bland, B. H., Kostopoulos, G. K., and Phillis J. W., 1974, Acetylcholine sensitivity of hippocampal formation neurons, Can. J. Physiol. Pharmacol. 52:966–971.
Bland, B. H., Andersen, P., and Ganes, T., 1975, Two generators of hippocampal theta activity in rabbits, Brain Res. 94:199–218.
Bliss, T. V. P., and Gardner-Medwin, A. R., 1973, Long-lasting potentiation of synaptic transmission in the dentate area of the unanesthetized rabbit following stimulation of the perforant path, J. Physiol. (London) 232:357–374.
Brown, D. A., 1983, Slow cholinergic excitation—a mechanism for increasing neuronal excitability, Trends Neurosci. 6:302–307.
Brown, D. A., Adams, and P. R., 1980, Muscarinic suppression of a novel voltage-sensitive K current in a vertebrate neurone, Nature 283:673–676.
Brown, D. A., and Griffith, W. H., 1983a, Calcium-activated outward current in voltage-clamped hippocampal neurones of the guinea-pig, J. Physiol. (London) 337:287–301.
Brown, D. A., and Griffith, W. H., 1983b, Persistent slow inward calcium current in voltage-clamped hippocampal neurones of the guinea pig, J. Physiol. (London)337:303–320.
Brown, D. A., Higgins, A. J., Marsh, S., and Smart, T. G., 1981, Actions of GABA on mammalian neurons, axons, and nerve terminals, in: Amino Acid Neurotransmitters (F. V. DeFeudis and P. Mandel, eds.), Raven Press, New York, pp. 321–326
Brown, T. H., and Johnston, D., 1980, Two classes of miniature synaptic potentials in CA3 hippocampal neurons, Soc. Neurosci. Abstr. 6:10.
Brown, T. H., and Johnston, D., 1983, Voltage-clamp analysis of mossy fiber synaptic input to hippocampal neurons, J. Neurophysiol. 50:487–507.
Brown, T. H., Wong, R. K. S., and Prince, D. A., 1979, Spontaneous miniature synaptic potentials in hippocampal neurons, Brain Res. 177:194–199.
Brown, T. H., Fricke, R. A., and Perkel, D. H., 1981, Passive electrical constants in three classes of hippocampal neurons, J. Neurophysiol. 46:812–827.
Buzsaki, G., and Eidelberg, E., 1982, Convergence of associational and commissural pathways on CA1 pyramidal cells of the rat hippocampus, Brain Res. 237:283–295.
Carlen, P. L., Gurevich, N., and Durand, D., 1982, Ethanol in low doses augments calcium-mediated mechanisms measured intracellularly in hippocampal neurons, Science 215:306–309.
Carlen, P. L., Gurevich, N., and Pole, P., 1983, Low-dose benzodiazepine neuronal inhibition: Enhanced Ca+ +-mediated K+ conductance, Brain Res. 271:358–364.
Chang, K. J., Cooper, B. R., Hazum, and E., Cuatrecasas, P., 1979, Multiple opiate receptors: Different regional distribution in the brain and differential binding of opiates and opioid peptides, Mol. Pharmacol. 16:91–104.
Collingridge, G. L., Kehl, S. J., and McLennan, H., 1983a, The antagonism of amino acid-induced excitations of rat hippocampal CA1 neurones in vitro, J. Physiol. (London) 334:19–31.
Collingridge, G. L., Kehl, S. J., and McLennan, H., 1983b, Excitatory amino acids in synaptic transmission in the Schaffer collateral—commissural pathway of the rat hippocampus, J. Physiol. (London)334:33–46.
Connors, B. W., and Prince, D. A., 1982, Effects of local anesthetic QX-314 on the membrane properties of hippocampal pyramidal neurons, J. Pharmacol. Exp. Ther. 200:476–481.
Connors, B. W., Gutnick, M. J., and Prince, D. A., 1982, Electrophysiological properties of neocortical neurons in vitro, J. Neurophysiol. 48:1302–1320.
Conrad, L. C. A., Leonard, C. M., and Pfaff, D W., 1974, Connections of the median and dorsal raphe nuclei in the rat: An autoradiographic and degeneration study, J. Comp. Neurol. 156:179–206.
Corrigall, W. A., and Linseman, M. A., 1980, A specific effect of morphine on evoked activity in the rat hippocampal slice, Brain Res. 192:227–238.
Cotman, C. W., and Nadler, J. V., 1978, Reactive synaptogenesis in the hippocampus, in: Neuronal Plasticity (C. W. Cotman, ed.), Raven Press, New York, pp. 227–271
Creager, R., Dunwiddie, T., and Lynch, G., 1980, Paired-pulse and frequency facilitation in the CA1 region of the in vitro rat hippocampus, J. Physiol. (London) 299:409–424.
Crill, W. E., and Schwindt, P. C., 1983, Active currents in mammalian central neurons, Trends Neurosci. 6:236–240.
Crunelli, V., Forda, S., and Kelly, J. S., 1983, Blockade of amino acid-induced depolarizations and inhibition of excitatory post-synaptic potentials in rat dentate gyrus, J. Physiol. (London) 341:627–640.
Crutcher, K. A., and Davis, J. N., 1980, Hippocampal alpha- and beta-adrenergic receptors: Comparisons of 3H-dihydroalprenolol and 3H-WB 4101 binding with noradrenergic innervation in the rat, Brain Res. 182:107–117.
Curtis, D. R., Felix, D., and McLennan, H., 1970, GABA and hippocampal inhibition, Br. J. Pharmacol. 40:881–883.
Dahl, D., Bailey, W. H., and Winson, J., 1983, Effect of norepinephrine depletion of hippocampus on neuronal transmission from perforant pathway through dentate gyrus, J. Neurophysiol. 49:123–133.
Daly, J. W., Bruns, R. F., and Snyder, S. H., 1981a, Adenosine receptors in the central nervous system: Relationship to the central actions of methylxanthines, Life Sci. 28:2083–2097.
Daly, J. W., Padgett, W., Creveling, C. R., Cantacuzene, D., and Kirk, K. L., 1981b, Cyclic AMP-generating systems: Regional differences in activation by adrenergic receptors in rat brain, J. Neurosci. 1:49–59.
Deadwyler, S. A., West, M., and Lynch, G., 1979, Activity of dentate granule cells during learning: Differentiation of perforant path input, Brain Res. 169:29–43.
Dichter, M., and Spencer, W. A., 1969a, Penicillin-induced interictal discharges from the cat hippocampus. I. Characteristics and topographical features, J. Neurophysiol. 32:649–662.
Dichter, M., and Spencer, W. A., 1969b, Penicillin-induced interictal discharges from the cat hippocampus. II. Mechanisms underlying origin and restriction, J. Neurophysiol. 32:663–687.
Dingledine, R., 1981, Possible mechanisms of enkephalin action on hippocampal CA1 pyramidal neurons, J. Neurosci. 1:1022–1035.
Dingledine, R., 1983, N-methyl aspartate activates voltage-dependent calcium conductance in rat hippocampal pyramidal cells, J. Physiol. (London) 343:385–405.
Dingledine, R., and Gjerstad, L., 1980, Reduced inhibition during epileptiform activity in the in vitro hippocampal slice, J. Physiol. (London) 305:297–313.
Dingledine, R., and Langmoen, I. A., 1980, Conductance changes and inhibitory actions of hippocampal recurrent IPSPs, Brain Res. 185:277–287.
Djørup, A., Jahnsen, H., and Mosfeldt-Laursen, A., 1981, The dendritic response to GABA in CA1 of the hippocampal slice, Brain Res. 219:196–201.
Dodd, J., and Kelly, J. S., 1978, In somatostatin an excitatory transmitter in the hippocampus?, Nature 273:674–675.
Dodd, J., and Kelly, J. S., 1981, The actions of cholecystokinin and related peptides on pyramidal neurones of the mammalian hippocampus, Brain Res.205:337–350.
Dodd, J., Kelly, J. S., and Said, S. I., 1979, Excitation of CA1 neurones of the rat hippocampus by the octacosapeptide, vasoactive intestinal polypeptide (VIP), Br. J. Pharmacol. 66:125P–125P
Dodd, J., Dingledine, R., and Kelly, J. S., 1981, The excitatory action of acetylcholine on hippocampal neurones of the guinea pig and rat maintained in vitro, Brain Res. 207:109–127.
Dolphin, A., Hamont, M., and Bockaert, J., 1979, The resolution of dopamine and beta-1 and beta-2 adrenergic-sensitive adenylate cyclase activities in homogenates of cat cerebellum, hippocampus, and cerebral cortex, Brain Res. 179:305–317.
Douglas, R. J., 1975, The development of hippocampal function: Implications for theory and for therapy, in: The Hippocampus Vol. 2 (R. L. Isaacson and K. H. Pribram, eds.), Plenum Press, New York, pp. 327–361
Douglas, R. M., Goddard, and G. V., 1975, Long-term potentiation of the perforant path—granule cell synapse in the rat hippocampus, Brain Res. 86:205–215.
Dudar, J. D., 1974, In vitro excitation of hippocampal pyramidal cell dendrites by glutamic acid, Neuropharmacology 13:1083–1089.
Dudar, J. D., 1975, The effect of septal nuclei stimulation on the release of acetylcholine from the rabbit hippocampus, Brain Res. 83:123–133.
Dudek, F. E., Andrew, R. D., MacVicar, B. A., Snow, R. W., and Taylor, C. P., 1983, Recent evidence for and possible significance of gap junctions and electrotonic synapses in the mammalian brain, in: Basic Mechanisms of Neuronal Hyperexcitability (H. H. Jasper and N. M. Van Gelder, eds.), Liss, New York, pp. 31–73
Dunwiddie, T. V., 1980, Endogenously released adenosine regulates excitability in the in vitro hippocampus, EPilepsia 21:541–548.
Dunwiddie, T. V., and Hoffer, B. J., 1980, Adenine nucleotides and synaptic transmission in the in vitro rat hippocampus, Br. J. Pharmacol. 69:59–68.
Dunwiddie, T., and Lynch, G., 1978, Long-term potentiation and depression of synaptic responses in the rat hippocampus: Localization and frequency dependency, J. Physiol. (London)276:353–367.
Dunwiddie, T., and Lynch, G., 1979, The relationship between extracellular calcium concentrations and the induction of hippocampal long-term potentiation, Brain Res. 169:103–110.
Dunwiddie, T., Madison, D., and Lynch, G., 1978, Synaptic transmission is required for long-term potentiation, Brain Res. 150:413–417.
Dunwiddie, T., Mueller, A., Palmer, M., Stewart, J., and Hoffer, B., 1980, Electrophysiological interactions of enkephalins with neuronal circuitry in the rat hippocampus. I. Effects on pyramidal cell activity, Brain Res. 184:311–330.
Dunwiddie, T. V., Hoffer, B. J., and Fredholm, B. B., 1981, Alkylxanthines elevate hippocampal excitability: Evidence for a role of endogenous adenosine, Naunyn-Schmiedebergs Arch. Pharmacol. 316:326–330.
Durand, D., Carlen, P. L., Gurevich, N., Ho, A., and Kunov, H., 1983, Electrotonic parameters of rat dentate granule cells measured using short current pulses and HRP staining, J. Neurophysiol. 50:1080–1097.
Eccles, J. C., 1955, The central action of antidromic impulses in motor nerve fibres, Pfluegers Arch. Gesamte Physiol. Menschen Tiere 260:385–415.
Eccles, J. C., 1983, Calcium in long-term potentiation as a model for memory, Neuroscience 10:1071–1081.
Eccles, J. C., Nicoll, R. A., Oshima, T., and Rubia, F. J., 1977, The anionic permeability of the inhibitory postsynaptic membrane of hippocampal pyramidal cells, Proc. R. Soc. London Ser. B 198:315–361.
Engel, J.,Jr., Kuhl, D. E., Phelps, M. E., and Crandall, P. H., 1982, Comparative localization of epileptic foci in partial epilepsy by PCT and EEG, Ann. Neurol. 12:529–537.
Enna, S. J., and Snyder, S. H., 1975, Properties of gamma-aminobutyric acid (GABA) binding in rat brain synaptic membrane fractions, Brain Res. 100:81–97.
Fagni, L., Baudry, M., and Lynch, G., 1983, Classification and properties of acidic amino acid receptors in hippocampus. I. Electrophysiological studies of an apparent desensitization and interactions with drugs which block transmission, J. Neurosci. 3:1538–1546.
Fantie, B. D., and Goddard, G. V., 1982, Septal modulation of the population spike in the fascia dentata produced by perforant path stimulation in the rat, Brain Res. 252:227–237.
Feldman, S. C., Dreyfus, C. F., and Lichtenstein, E. S., 1982, Somatostatin neurons in the rodent hippocampus: An in vitro and in vivo immunocytochemical study, Neurosci. Lett. 33:29–34.
Fifkova, E., and Van Harreveld, A., 1977, Long-lasting morphological changes in dendritic spines of dentate granular cells following stimulation of the entorhinal area, J. Neurocytol. 6:211–230.
Fisher, R. S., Pedley, T. A., Moody, W. J., Jr., and Prince, D. A., 1976, The role of extracellular potassium in hippocampal epilepsy, Arch. Neurol. 33:76–83.
Fox, S. E., Ranck, and J. B., Jr., 1981, Electrophysiological characteristics of hippocampal complexspike cells and theta cells, Exp. Brain Res. 41:399–410.
Fredholm, B. B., and Hedqvist, P., 1980, Modulation of neurotransmission by purine nucleotides and nucleosides, Biochem. Pharmacol. 29:1635–1643.
Frotscher, M., and Zimmer, J., 1983, Commissural fibers terminate on non-pyramidal neurons in the guinea pig hippocampus—A combined Golgi/EM degeneration study, Brain Res. 265:289–293.
Fujita, Y., 1975, Two types of depolarizing after-potentials in hippocampal pyramidal cells of rabbits, Brain Res. 94:435–446.
Fujita, Y., 1979, Evidence for the existence of inhibitory postsynaptic potentials in dendrites and their functional significance in hippocampal pyramidal cells of adult rabbits, Brain Res. 175:59–69.
Fuxe, K., 1965, Evidence for the existence of monoamine neurons in the central nervous system. IV. The distribution of monoamine terminals in the central nervous system, Acta Physiol. Scand. SuliPl. 247:37–85.
Gaffan, D., 1974, Recognition impaired and association intact in the memory of monkeys after transection of the fornix, J. Comp. Physiol. Psychol. 86:1100–1109.
Gage, F. H., and Thompson, R. G., 1980, Differential distribution of norepinephrine and serotonin along the dorsal—ventral axis of the hippocampal formation, Brain Res. Bull. 5:771–773.
Gähwiler, B. H., 1980, Excitatory action of opioid peptides and opiates on cultured hippocampal pyramidal cells, Brain Res. 194:193–203.
Gähwiler, B. H., and Maurer, R., 1981, Involvement of mu-receptors in the opioid-induced generation of bursting discharges in hippocampal pyramidal cells, Regul. Peptides 2:91–96.
Gall, C., Brecha, N., Karten, H. J., and Chang, K. J., 1981, Localization of enkephalin-like immunoreactivity to identified axonal and neuronal populations of the rat hippocampus, J. Comp. Neurol. 198:335–350.
Gottlieb, D. I., and Cowan, W. M., 1972, On the distribution of axon terminals containing spheroidal and flattened synaptic vesicles in the hippocampus and dentate gyrus of the rat and cat, Z. Zellforsch. 129:413–429.
Green, J. D., 1964, The hippocampus, Physiol. Rev. 44:561–608.
Green, J.D., and Petsche, H., 1961, Hippocampal electrical activity. IV. Abnormal electrical activity, Electroencephalogr. Clin. Neurophysiol. 13:868–879.
Green, J. D., Maxwell, D. S., Schindler, W. J., and Stumpf, C., 1960, Rabbit EEG “theta” rhythm: Its anatomical source and relation to activity in single neurons, J. Neurophysiol. 23403–420
Gustafsson, B., Galvan, M., Grafe, P., and Wigstrom, H., 1982, A transient outward current in a mammalian central neurone blocked by 4-aminopyridine, Nature 299:252–254.
Haas, H. L., 1981, Histamine hyperpolarizes hippocampal neurones in vitro, Neurosci. Lett. 22:75–78.
Haas, H. L., 1982, Cholinergic disinhibition in hippocampal slices of the rat, Brain Res. 233:200–204.
Haas, H. L., and Ryall, R. W., 1980, Is excitation by enkephalins of hippocampal neurones in the rat due to presynaptic facilitation or to disinhibition?, J. Physiol. (London) 308:315–330.
Haas, H. L., and Wolf, P., 1977, Central actions of histamine: Microelectrophoretic studies, Brain Res. 122:269–279.
Haas, H. L., Wolf, P., Palacios, J. M., Garbarg, M., Barbin, G., and Schwartz, J.-C., 1978, Hypersensitivity to histamine in the guinea pig brain: Microiontophoretic and biochemical studies, Brain Res. 156:275–291.
Haas, H. L., Felix, D., Celio, M. R., and Inagami, T., 1980, Angiotensin II in the hippocampus: A histochemical and electrophysiological study, Experientia 36:1394–1395.
Hablitz, J. J., 1981, Altered burst responses in hippocampal CA3 neurons injected with EGTA, Exp. Brain Res. 42:483–485.
Hablitz, J. J., and Johnston, D., 1981, Endogenous nature of spontaneous bursting in hippocampal pyramidal neurons, Cell. Mol. Neurobiol. 1:325–334.
Hablitz, J. J., and Langmoen, I. A., 1982, Excitation of hippocampal pyramidal cells by glutamate in the guinea pig and rat, J. Physiol. (London) 325:317–331.
Halliwell, J. V., and , P. R., 1982, Voltage-clamp analysis of muscarinic excitation in hippocampal neurons, Brain Res. 250:71–92.
Hamlyn, L. H., 1963, An electron microscope study of pyramidal neurons in the Ammon’s horn of the rabbit, J. Anat. 97:189–201.
Handelmann, G. E., Meyer, D. K., Beinfeld, M. C., and Oertel, W. H., 1981, CCK-containing terminals in the hippocampus and derived from intrinsic neurons: An immunohistochemical and radioimmunological study, Brain Res. 224:180–184.
Henriksen, S. J., Chouvet, G., and Bloom, F., 1983, Differential responses of hippocampal neurons to endogenous opioid peptides, and opiate alkaloids suggest multiple opiate receptorsSoc. Neurosci. Abstr. 9:1130.
Herrling, P L., 1981, The membrane potential of cat hippocampal neurons recorded in vivo displays four different reaction-mechanisms to iontophoretically applied transmitter agonists, Brain Res. 212:331–343.
Hicks, T. P., and McLennan, H., 1979, Amino acids and the synaptic pharmacology of granule cells in the dentate gyrus of the rat, Can. J. Physiol. Pharmacol. 57:973–978.
Hill, D. R., and Bowery, N. G., 1981, 3H-baclofen and 3H-GABA bind to bicuculline-insensitive GABAB sites in rat brain, Nature 290:149–152.
Hjorth-Simonsen, A., and Jeune, B., 1972, Origin and termination of the hippocampal perforant path in the rat studied by silver impregnation, J. Comp. Neurol. 144:215–232.
Hodgkin, A. L., and Huxley, A. F., 1952, A quantitative description of membrane current and its application to conduction and excitation in nerve, J. Physiol. (London) 117:500–544.
Hoffer, B. J., Seiger, Å., Taylor, D., Olson, L., and Freedman, R., 1977, Seizures and related epileptiform activity in hippocampus transplanted to the anterior chamber of the eye, Exp. Neurol. 54:233–250.
Hökfelt, T., Ljungdahl, Á., Fuxe, K., and Johansson, O., 1974, Dopamine nerve terminals in the rat limbic cortex: Aspects of the dopamine hypothesis of schizophrenia, Science 184:177–179.
Hong, J.-S., and Schmid, R., 1981, Intrahippocampal distribution of Met5-enkephalin, Brain Res. 205:415–418.
Hong, J.-S., Yang, H. Y., Fratta, W., and Costa, E., 1977, Determination of methionine-enkephalin in discrete regions of rat brain, Brain Res. 134:383–386.
Horowitz, J. M., and Mates, J. W B., 1975, Signal dispersion within a hippocampal neural network, Comput. Biol. Med. 5:283–296.
Hotson, J. R., and Prince, D. A., 1980, A calcium activated hyperpolarization follows repetitive firing in hippocampal neurons, J. Neurophysiol. 43:409–419.
Hotson, J. R., Prince, D. A., and Schwartzkroin, P. A., 1979, Anomalous inward rectification in hippocampal neurons, J. Neurophysiol. 42:889–895.
Hounsgaard, J., 1978, Presynaptic inhibitory action of acetylcholine in area CA1 of the hippocampus, Exp. Neurol. 62:787–797.
Isaacson, R. L., and Pribram, K. H. (eds.), 1975, The Hippocampus Vols. 1 and 2, Raven Press, New York
Ishikawa, K., Ott, T., and McGaugh, J. L., 1982, Evidence for dopamine as a transmitter in dorsal hippocampus, Brain Res. 232:222–226.
Jahnsen, H., 1980, The action of 5-hydroxytryptamine on neuronal membranes and synaptic transmission in area CA1 of the hippocampus in vitro, Brain Res. 197:83–94.
Jefferys, J. G. R., and Haas, H L., 1982, Synchronized bursting of CA1 hippocampal pyramidal cells in the absence of synaptic transmission, Nature 300:448–450.
Johnston, D., 1981, Passive cable properties of hippocampal CA3 pyramidal neurons, Cell. Mol. Neurobiol. 1:41–55.
Johnston, D., and Brown, T. H., 1981, Giant synaptic potential hypothesis for epileptiform activity, Science 211:294–297.
Johnston, D., and Brown, T. H., 1983, Interpretation of voltage-clamp measurements in hippocampal neurons, J. Neurophysiol. 50:464–486.
Johnston, D., and Brown, T. H., 1984, Mechanisms of neuronal burst generation, in: Electrophysiology of Epilepsy (P. A. Schwartzkroin and H. V. Hweal, eds.), Academic Press, New York, pp. 277–301
Johnston, D., Hablitz, J. J., and Wilson, W. A., 1980, Voltage clamp discloses slow inward current in hippocampal burst-firing neurones, Nature 286:391–393.
Jones, B. E., and Moore, R. Y., 1977, Ascending projections of the locus coeruleus in the rat. II. Autoradiographic study, Brain Res. 127:23–53.
Kandel, E. R., and Spencer, W. A., 1961, Electrophysiology of hippocampal neurons. II. After-potentials and repetitive firing, J. Neurophysiol. 24:243–259.
Kandel, E. R., Spencer, W. A., and Brinley, F. J., Jr., 1961, Electrophysiology of hippocampal neurons. I. Sequential invasion and synaptic organization, J. Neurophysiol. 24:225–242.
Knowles, W. D., and Schwartzkroin, P. A., 1981, Local circuit synaptic interactions in hippocampal brain slices, J. Neurosci. 1:318–322.
Knowles, W. D., Funch, P. G., and Schwartzkroin, P. A., 1982a, Electrotonic and dye coupling in hippocampal CA1 pyramidal cells in vitro, Neuroscience 7:1713–1722.
Knowles, W. D., Schwartzkroin, P. A, and Schneiderman, J. H., 1982b, Three types of hyperpolarizations in hippocampal CA3 neurons, Soc. Neurosci. Abstr. 8:412.
Kostopoulos, G. K., and Phillis, J. W., 1977, Purinergic depression of neurons in different areas of the rat brain, Exp. Neurol. 55:791–824.
Kramis, R., Vanderwolf, C. H., and Bland, B. H., 1975, Two types of hippocampal rhythmical slow activity in both the rabbit and the rat: Relations to behavior and effects of atropine, diethylether, urethane, and pentobarbital, Exp. Neurol. 49:58–85.
Krnjevć, K., and Ropert, N., 1981, Septo-hippocampal pathway modulates hippocampal activity by a cholinergic mechanism, Can. J. Physiol. Pharmacol. 59:911–914.
Krnjevć, K., and Ropert, N., 1982, Electrophysiological and pharmacological characteristics of facilitation of hippocampal population spikes by stimulation of the medial septum, Neuroscience 7:2165–2183.
Krnjević, K., Morris, M. E., and Reiffenstein, R. J., 1980, Changes in extracellular Ca+ + and K+ activity accompanying hippocampal discharges, Can. J. Physiol. Pharmacol. 58:579–583.
Kromer, L. F., Björklund, A., and Stenevi, U., 1981, Regeneration of the septohippocampal pathway in adult rats is promoted by utilizing embryonic hippocampal implants as bridges, Brain Res. 210:173–200.
Kuhar, M. J., and Yamamura, H. I., 1976, Localization of cholinergic muscarinic receptors in rat brain by light microscopic radioautography, Brain Res. 110:229–243.
Kuhar, M. J., Taylor, N., Wamsley, J. K., Hulme, E. C., and Birdsall, N. J. M., 1981, Muscarinic cholinergic receptor localization in brain by electron microscopic autoradiography, Brain Res. 216:1–9.
Kunkel, D. D., and Schwartzkroin, P. A., 1982, Interneuron morphology in the CA1 region of rabbit hippocampus, Soc. Neurosci. Abstr. 8:216.
Kunkel, D. D., Schwartzkroin, P. A., and Hendrickson, A. E., 1983, Immunocytochemistry of somatostatin in CA1 of rabbit hippocampus, Soc. Neurosci. Abstr. 9:218.
Langmoen, I. A., Segal, M., and Andersen, P., 1981, Mechanisms of norepinephrine actions on hippocampal pyramidal cells in vitro, Brain Res. 208:349–362.
Lebovitz, R. M., Dichter, M., and Spencer, W. A., 1971, Recurrent excitation in the CA3 region of cat hippocampus, Int. J. Neurosci. 2:99–108.
Lee, H. K., Dunwiddie, T., and Hoffer, B., 1980, Electrophysiological interactions of enkephalins with neuronal circuitry in the rat hippocampus. II. Effects on interneuron excitability, Brain Res. 184:331–342.
Lee, K., and Schubert, P., 1982, Modulation of an inhibitory circuit by adenosine and AMP in the hippocampus, Brain Res. 246:311–314.
Lee, K., Schubert, P., Gribkoff, V., Sherman, B., and Lynch, G., 1982, A combined in vivo/in vitro study of the presynaptic release of adenosine derivatives in the hippocampus, J. Neurochem. 38:80–83.
Lee, K. S., Reddington, M., Schubert, P., and Kreutzberg, G., 1983a, Regulation of the strength of adenosine modulation in the hippocampus by a differential distribution of the density of A1 receptors, Brain Res. 260:156–159.
Lee, K. S., Schubert, P., Reddington, M., and Kreutzberg, G. W., 1983b, Adenosine receptor density and the depression of evoked neuronal activity in the rat hippocampus in vitro, Neurosci. Lett. 37:81–85.
Leung, L. S., 1978, Hippocampal CA1 region—Demonstration of antidromic dendritic spike and dendritic inhibition, Brain Res. 158:219–222.
Levy, W. B., and Steward, O., 1983, Temporal contiguity requirements for long-term associative potentiation/depression in the hippocampus, Neuroscience 8:791–797.
Lewis, E. R., and Cotman, C. W., 1980, Mechanisms of septal lamination in the developing hippocampus revealed by outgrowth of fibers from septal implants. I. Positional and temporal factors, Brain Res. 196:307–330.
Lewis, P. R., Shute, C. C. D., and Silver, A., 1967, Confirmation from choline acetylase analyses of a massive cholinergic innervation to the rat hippocampus, J. Physiol. (London)191:215–224.
Lieb, J. P., Engel, J. E., Jr., Gevins, A., and Crandall, P. H., 1981, Surface and deep EEG correlates of surgical outcome in temporal lobe epilepsy, EPilepsia 22:515–538.
Lindvall, O., and Björklund, A., 1974, The organization of the ascending catecholamine neuron system in the rat brain as revealed by the glyoxylic acid fluorescence method, Acta Physiol. Scand. 412:1–48.
Llinás, R., and Jahnsen, H., 1982, Electrophysiology of mammalian thalamic neurones in vitro, Nature 297:406–408.
Llinás, R., and Sugimori, M., 1980a, Electrophysiological properties of in vitro Purkinje cell somata in mammalian cerebellar slices, J. Physiol. (London)305:171–195.
Llinás, R., and Sugimori, M., 1980b, Electrophysiological properties of in vitro Purkinje cell dendrites in mammalian cerebellar slices, J. Physiol. (London) 305:197–213.
Llinás, R., and Yarom, Y., 1981a, Electrophysiology of mammalian inferior olivary neurones in vitro: Different types of voltage-dependent ionic conductances, J. Physiol. (London) 315:549–567.
Llinś, R., and Yarom, Y., 1981b, Properties and distribution of ionic conductances generating electroresponsiveness of mammalian inferior olivary neurones in vitro, J. Physiol. (London)315:569–584.
Lømo, T., 1971a, Patterns of activation in a monosynaptic cortical pathway: The perforant path input to the dentate area of the hippocampal formation, Exp. Brain Res. 12:18–45.
Lømo, T., 1971b, Potentiation of monosynaptic EPSPs in the perforant path—dentate granule cell synapse, Exp. Brain Res. 12:46–63.
Lorente de Nó, R., 1934, Studies on the structure of the cerebral cortex II. Continuation of the study of the ammonic system, J. Psychol. Neurol. 46:113–177.
Low, W. C., and BeMent, S. L., 1980, Enhancement of afferent fiber activity in hippocampal slices, Brain Res. 198:472–477.
Low, W. C., BeMent, S. L., and Whitehorn, D., 1983, Field-potential evidence for extrasynaptic alterations in the hippocampal CA1 pyramidal cell population during paired-pulse potentiation, Exp. Neurol. 80:9–22.
Lundberg, J. M., and Hökfelt, T., 1983, Coexistence of peptides and classical neurotransmitters, Trends Neurosci. 6:325–333.
Lux, H. D., and Pollen, D. A., 1966, Electrical constants of neurons in the motor cortex of the cat, J. Neurophysiol. 29:207–220.
Lynch, G., and Cotman, C. W., 1975, The hippocampus as a model for studying anatomical plasticity in the adult brain, in: The Hippocampus Vol. 1 (R. L. Isaacson and K. H. Pribram, eds.), Plenum Press, New York, pp. 123–154
Lynch, G. S., Dunwiddie, T., and Gribkoff, V., 1977, Heterosynaptic depression: A postsynaptic correlate of long-term potentiation, Nature 266:737–739.
Lynch, G. S., Jensen, R. A., McGaugh, J. L., Davila, K., and Oliver, M. W., 1981, Effects of enkephalin, morphine, and naloxone on the electrical activity of the in vitro hippocampal slice preparation, Exp. Neurol. 71:527–540.
McGinty, J. F., Henriksen, S. J., Goldstein, A., Terenius, L., and Bloom, F. E., 1983, Dynorphin is contained within hippocampal mossy fibers: Immunochemical alterations after kainic acid administration and colchicine-induced neurotoxicity, Proc. Natl. Acad. Sci. USA 80:589–593.
McNaughton, B. L., 1980, Evidence for two physiologically distinct perforant pathways to the fascia dentata, Brain Res. 199:1–19.
McNaughton, B. L., 1982, Long-term synaptic enhancement and short-term potentiation in rat fascia dentata act through different mechanisms, J. Physiol. (London)324:249–262.
McNaughton, B. L., and Barnes, C. A., 1977, Physiological identification and analysis of dentate granule cell responses to stimulation of the medial and lateral perforant pathways in the rat, J. Comp. Neurol. 175:439–454.
McNaughton, B. L., Douglas, R. M., and Goddard, G. V., 1978, Synaptic enhancement in fascia dentata: Cooperativity among coactive afferents, Brain Res. 157:277–293.
McNaughton, B. L., Barnes, C. A., and Andersen, P., 1981, Synaptic efficacy and EPSP summation in granule cells of rat fascia dentata studied in vitro, J. Neurophysiol. 46:952–966.
MacVicar, B. A., and Dudek, F. E., 1980a, Local synaptic circuits in rat hippocampus: Interaction between pyramidal cells, Brain Res. 184:220–223.
MacVicar, B. A., and Dudek, F. E., 1980b, Dye-coupling between CA3 pyramidal cells in slices of rat hippocampus, Brain Res. 196:494–497.
MacVicar, B. A., and Dudek, F. E., 1981, Electrotonic coupling between pyramidal cells: A direct demonstration in rat hippocampal slices, Science 213:782–785.
MacVicar, B. A., and Dudek, F. E., 1982, Electrotonic coupling between granule cells of rat dentate gyrus: Physiological and anatomical evidence, J. Neurophysiol. 47579–592
Madison, D. V., and Nicoll, R. A., 1982, Noradrenalin blocks accommodation of pyramidal cell discharge in the hippocampus, Nature 299:636–638.
Madison, D. V., and Nicoll, R. A., 1983, Adaptation of action potential frequency in hippocampal pyramidal cells is regulated by calcium-activated potassium conductance and M-current, Soc. Neurosci. Abstr. 9:601.
Marks, M. J., and Collins, A. C., 1982, Characterization of nicotine binding in mouse brain and comparison with the binding of alpha-bungarotoxin and quinuclidinyl benzilate, Mol. Pharmacol. 22:554–564.
Masukawa, L. M., and Prince, D. A., 1982, Enkephalin inhibition of inhibitory input to CA1 and CA3 pyramidal neurons in the hippocampus, Brain Res. 249:271–280.
Matthews, W. D., McCafferty, G. P., and Setler, P. E., 1981, An electrophysiological model of GABA-mediated neurotransmission, Neuropharmacology 20:561–565.
Minkwitz, H.-G., 1976, Zur Entwicklung der Neuronenstruktur des Hippocampus wahrend der Pra- and Postnatalen Ontogenese der Albinoratte. III. Mitteilung: Morphometrische Erfassung der Ontogenetischen Veranderungen in Dendriten Struktur und Spine Besatz an Pyramiden-Neuronen (CA1) des Hippocampus, J. Hirnforsch. 17:255–275.
Misgeld, U., Sarvey, J. M., and Klee, M. R., 1979, Heterosynaptic postactivation potentiation in hippocampal CA3 neurons: Long-term changes of the postsynaptic potential, Exp. Brain Res. 37:217–229.
Moore, R. Y., 1975, Monoamine neurons innervating the hippocampal formation and septum: Organization and response to injury, in: The Hippocampus Vol. 1 (R. L. Isaacson and K. H. Pribram, eds.), Plenum Press, New York, pp. 215–237
Moore, R. Y., and Halaris, A. E., 1975, Hippocampal innervation by serotonin neurons of the midbrain raphe in the rat, J. Comp. Neurol. 164:171–184.
Mueller, A. L., and Dunwiddie, T. V., 1983, Anticonvulsant and proconvulsant actions of alpha-and beta-noradrenergic agonists on epileptiform activity in rat hippocampus in vitro, EPilepsia 24:57–64.
Mueller, A. L., and Schwartzkroin, P. A., 1983, Electrophysiological actions of somatostatin (SRIF) in rabbit hippocampus studied in vitro, Soc. Neurosci. Abstr. 9:219.
Mueller, A. L., Hoffer, B. J., and Dunwiddie, T. V., 1981, Noradrenergic responses in rat hippocampus: Evidence for mediation by α and ß receptors in the in vitro slice, Brain Res. 214:113–126.
Mueller, A. L., Palmer, M. R., Hoffer, B. J., and Dunwiddie, T. V., 1982, Hippocampal noradrenergic responses in vivo and in vitro: Characterization of alpha and beta components, Naunyn-Schmiedebergs Arch. Pharmacol. 318:259–266.
Mueller, A. L., Chesnut, R. M., and Schwartzkroin, P. A., 1983, Actions of GABA in developing rabbit hippocampus: An in vitro study, Neurosci. Lett. 39:193–198.
Mühlethaler, M., Dreifuss, J. J., and Gähwiler, B. H., 1982, Vasopressin excites hippocampal neurones, Nature 296:749–751.
Mühlethaler, M., Sawyer, W. H., Manning, M. M., and Dreifuss, J. J., 1983, Characterization of a uterine-type oxytocin receptor in the rat hippocampus, Proc. Natl. Acad. Sci. USA 80:6713–6717.
Muller, R. U., Kubie, J. L., and Ranck, J. B., Jr., 1983, High resolution mapping of the “spatial” fields of hippocampal neurons in the freely moving rat, Soc. Neurosci. Abstr. 9:646.
Nadler, J. V., Vaca, K. W., White, W. F., Lynch, G. S., and Cotman, C. W., 1976, Aspartate and glutamate as possible transmitters of excitatory hippocampal afferents, Nature 260:538–540.
Nadler, J. V., White, W. F., Vaca, K. W., Redburn, D. A., and Cotman, C. W., 1977, Characterization of putative amino acid transmitter release from slices of rat dentate gyrus, J. Neurochem. 29:279–290.
Nadler, J. V., White, W. F., Vaca, K. W., Perry, B. W., and Cotman, C. W., 1978, Biochemical correlates of transmission mediated by glutamate and aspartate, J. Neurochem. 31:147–155.
Newberry, N. R., and Nicoll, R. A., 1983, Direct inhibitory action of baclofen on hippocampal pyramidal cells, Soc. Neurosci. Abstr. 9:457.
Nicoll, R. A., and Alger, B. E., 1981, Synaptic excitation may activate a calcium-dependent potassium conductance in hippocampal pyramidal cell, Science 212:957–959.
Nicoll, R. A., Siggins, G. R., Ling, N., Bloom, F. E., and Guillemen, R., 1977, Neuronal actions of endorphins and enkephalins among brain regions: A comparative microiontophoretic study, Proc. Natl. Acad. Sci. USA 74:2584–2588.
Nicoll, R. A., Alger, B. E., and Jahr, C. E., 1980, Enkephalin blocks inhibitory pathways in the vertebrate CNS, Nature 287:22–25.
Numann, R., Wong, R. K. S., and Clark, R., 1982, Electrophysiology of single dissociated cortical neurons, Soc. Neurosci. Abstr. 8:413.
Okada, Y., and Ozawa, S., 1980, Inhibitory action of adenosine on synaptic transmission in the hippocampus of the guinea pig in vitro, Eur. J. Pharmacol. 68:483–492.
Okada, Y., and Shimada, C., 1975, Distribution of γ-aminobutyric acid (GABA) and glutamate decarboxylase (GAD) activity in the guinea pig hippocampus—Microassay method for the determination of GAD activity, Brain Res. 98:202–206.
O’Keefe, J., and Nadel, L., 1978, The Hippocampus as a Cognitive Map, Oxford University Press, London
Olds, J., 1972, Learning and the hippocampus, Rev. Can. Bio. Suppl. 31:215–238.
Olds, J., Disterhoft, J. F., Segal, M., Kornblith, C. L., and Hirsh, R., 1972, Learning centers of rat brain mapped by measuring latencies of conditioned unit responses, J. Neurophysiol. 35:202–219.
Olpe, H.-R., Balcar, V. J., Bittiger, H., Rink, H., and Sieber, P., 1980, Central actions of somatostatin, Eur. J. Pharmacol. 63:127–133.
Olsen, R. W., Bergman, M O., VanNess, P. C., Lummis, S. C, Watkins, A. E., Napias, C., and Greenlee, D. V., 1981, Gamma-aminobutyric acid receptor binding in mammalian brain: Heterogeneity of binding sites, Mol. Pharmacol. 19:217–227.
Olton, D. S., Becker, J. T., and Handelmann, G. E., 1979, Hippocampus, space, and memory, Behav. Brain Sci. 2:313–365.
Palacios, J. M., DeHaven, R. N., and KuharM. J., 1980, Localization of beta-adrenergic receptors in rat brain by light microscopic autoradiography, Fed. Proc. 39:593.
Peroutka, S. J., and Snyder, S. H., 1981, Two distinct serotonin receptors: Regional variations in receptor binding in mammalian brain, Brain Res. 208:339–347.
Petsche, H., Stumpf, C., and Gogolak, G., 1962, The significance of the rabbit’s septum as a relay station between midbrain and hippocampus. I. The control of hippocampus arousal activity by septum cells, Electroencephalogr. Clin. Neurophysiol. 14:201–211.
Pittman, Q. J., and Siggins, G. R., 1981, Somatostatin hyperpolarized hippocampal pyramidal cells in vitro, Brain Res. 221:402–408.
Prince, D. A., 1983, Ionic mechanisms in cortical and hippocampal epileptogenesis, in: Basic Mechanisms of Neuronal Hyperexcitability (H. H. Jasper and N. VanGelder, eds.), Liss, New York, pp. 217–243
Proctor, W. R., and Dunwiddie, T. V., 1983, Adenosine inhibits calcium spikes in hippocampal pyramidal neurons in vitro, Neurosci. Lett. 35:197–201.
Purpura, D. P., and Malliani, A., 1966, Spike generation and propagation initiated in dendrites by transhippocampal polarization, Brain Res. 1:403–406.
Purpura, D. P., Prelevic, S., and Santini, M., 1968, Hyperpolarizing increase in membrane conductance in hippocampal neurons, Brain Res. 7:310–312.
Racine, R. J., and Milgram, N. W., 1983, Short-term potentiation phenomena in the rat limbic forebrain, Brain Res. 260:201–216.
Racine, R. J., Milgram, N. W., and Hafner, S., 1983, Long-term potentiation phenomena in the rat limbic forebrain, Brain Res. 260:217–231.
Raisman, G., 1966, The connexions of the septum, Brain 89:317–348.
Rall, W., 1969, Time constants and electrotonic length constants of membrane cylinders and neurons, Biophys. J. 9:1483–1508.
Rall, W., 1974, Dendritic spines, synaptic potency and neuronal plasticity, in: Cellular Mechanisms Subserving Changes in Neuronal Activity (C. D. Woody, K. A. Brown, T. J. Crow, and J. D. Knispe, eds.), Brain Information Service, UCLA, Los Angeles, pp. 13–21
Rall, W., 1977, Core conductor theory and cable properties of neurons, in: Handbook of Physiology, The Nervous System Section I (E. R. Kandel, ed.), Williams & Wilkins, Baltimore, pp. 39–98
Rall, W., and Rinzel, J., 1973, Branch input resistance and steady attenuation for input to one branch of a dendritic neuron model, Biophys. J. 13:648–688.
Ramón y Cajal, S., 1911, Histologie du systemé nerveux de l’Homme et des Vertébrés Maloine, Paris
Ranck, J. B., Jr., 1973, Studies on single neurons in dorsal hippocampal formation and septum in unrestrained rats. Part 1. Behavioral correlates and firing repertoires, Exp. Neurol. 41:461–534.
Reddington, M., Lee, K., and Schubert, P., 1982, An A1-adenosine receptor characterized by 3H-cyclohexyladenosine binding, moderates the depression of evoked potentials in a rat hippocampal slice preparation, Neurosci. Lett. 28:275–279.
Ribak, C. E., Vaughn, J. E., and Saito, K., 1978, Immunocytochemical localization of glutamic acid decarboxylase in neuronal somata following colchicine inhibition of axonal transport, Brain Res. 140:315–332.
Robinson, J. H., and Deadwyler, S. A., 1981, Intracellular correlates of morphine excitation in the hippocampal slice preparation, Brain Res. 224:375–387.
Rose, A. M., Hattori, T., and Fibiger, H. C., 1976, Analysis of the septo-hippocampal pathway by light and electron microscopic autoradiography, Brain Res. 108:170–174.
Salmoiraghi, G. C., and Stefanis, C. N., 1965, Patterns of central neuron responses to suspected transmitters, Arch. Ital. Biol. 103:705–724.
Sandoval, M. E., Horch, P., and Cotman, C. W., 1978, Evaluation of glutamate as a hippocampal neurotransmitter: Glutamate uptake and release from synaptosomes, Brain Res. 142:285–299.
Sastry, B. R., 1982, Presynaptic change associated with long-term potentiation in hippocampus, Life Sci. 30:2003–2008.
Sawada, S., Takada, S., and Yamamoto, C., 1982, Excitatory actions of homocysteic acid on hippocampal neurons, Brain Res. 238:282–285.
Scatton, B., Simon, H., Le Moal, M., and Bischoff, S., 1980, Origin of dopaminergic innervation of the rat hippocampal formation, Neurosci. Lett. 18:125–131.
Schmalbruch, H., and Jahnsen, H., 1981, Gap junctions on CA3 pyramidal cells of guinea pig hippocampus shown by freeze fracture, Brain Res. 217:175–178.
Schubert, P., and Mitzdorf, U., 1979, Analysis and quantitative evaluation of the depressive effect of adenosine on evoked potentials in hippocampal slices, Brain Res. 172:186–190.
Schwartz, J.-C., Barbin, G., Duchemin, A. M., Garbarg, M., Palacios, J. M., Quach, T. T., and Rose, C., 1980, Histamine receptors in brain: Characterization by binding studies and biochemical effects, in: Receptors for Neurotransmitters and Peptide Hormones (G. Pepeu, M. J. Kuhar, and S. J. Enna, eds.), Raven Press, New York, pp. 169–182
Schwartzkroin, P. A., 1975, Characteristics of CA1 neurons recorded intracellularly in the hippocampal in vitro slice preparation, Brain Res. 85:423–436.
Schwartzkroin, P. A., 1983a, Mechanisms of cell synchronization in epileptiform activity, Trends Neurosci. 6:157–160.
Schwartzkroin, P. A., 1983b, Local circuit considerations and intrinsic neuronal properties involved in hyperexcitability and cell synchronization, in: Basic Mechanisms of Neuronal Hyperexcitability (N. VanGelder and H. H. Jasper, eds.), Liss, New York, pp. 75–108
Schwartzkroin, P. A., and Andersen, P., 1975, Glutamic acid sensitivity of dendrites in hippocampal slices in vitro, in: Physiology and Pathology of Dendrites (G. Kreutzberg, ed.), Raven Press, New York, pp. 45–51
Schwartzkroin, P. A., and Knowles, W. D., 1983, Local interactions in the hippocampus, Trends Neurosci. 6:88–92.
Schwartzkroin, P. A., and Mathers, L. H., 1978, Physiological and morphological identification of a nonpyramidal hippocampal cell type, Brain Res. 157:1–10.
Schwartzkroin, P. A., and Pedley, T. A., 1979, Slow depolarizing potentials in “epileptic” neurons, Epilepsia 20:267–277.
Schwartzkroin, P. A., and Prince, D. A., 1977, Penicillin-induced epileptiform activity in the hippocampal in vitro preparation, Ann. Neurol. 1:463–469.
Schwartzkroin, P. A., and Prince, D. A., 1978, Cellular and field potential properties of epileptogenic hippocampal slices, Brain Res. 147:117–130.
Schwartzkroin, P. A., and PrinceD. A., 1979, Recordings from presumed glial cells in the hippocampal slice, Brain Res. 161:533–538.
Schwartzkroin, P. A., and Prince, D. A., 1980a, Effects of TEA on hippocampal neurons, Brain Res. 185:169–181.
Schwartzkroin, P. A., and Prince, D. A., 1980b, Changes in excitatory and inhibitory synaptic potentials leading to epileptogenic activity, Brain Res. 183:61–76.
Schwartzkroin, P. A., and Slawsky, M., 1977, Probable calcium spike in hippocampal neurons, Brain Res. 135:157–161.
Schwartzkroin, P. A., and Stafstrom, C. E., 1980, Effects of EGTA on the calcium-activated after-hyperpolarization in hippocampal CA3 pyramidal cells, Science 210:1125–1126.
Schwartzkroin, P. A., and Wester, K., 1975, Long-term facilitation of a synaptic potential following tetanization in the in vitro hippocampal slice, Brain Res. 89:107–119.
Schwartzkroin, P. A., and Wyler, A. R., 1980, Mechanisms underlying epileptiform burst discharge, Ann. Neurol. 7:95–107.
Schwartzkroin, P. A., Kunkel, D. D., and Mathers, L. H., 1982, Development of rabbit hippocampus: Anatomy, Dev. Brain Res. 2:453–468.
Scoville, W. B., and Milner, B., 1957, Loss of recent memory after bilateral hippocampal lesions, J. Neurol. Neurosurg. Psychiatry 20:11–21.
Segal, M., 1975, Physiological and pharmacological evidence for a serotonergic projection to the hippocampus, Brain Res. 94:115–131.
Segal, M., 1980a, The action of serotonin in the rat hippocampal slice preparation, J. Physiol. (London)303:423–439.
Segal, M., 1980b, Histamine produces a Ca+2-sensitive depolarization of hippocampal pyramidal cells in vitro, Neurosci. Lett. 19:67–71.
Segal, M., 1981a, The action of norepinephrine in the rat hippocampus: Intracellular studies in the slice preparation, Brain Res. 206:107–128.
Segal, M., 1981b, Histamine modulates reactivity of hippocampal CA3 neurons to afferent stimulation in vitro, Brain Res. 213:443–448.
Segal, M., 1981c, Regional differences in neuronal responses to 5-HT: Intracellular studies in hippocampal slices, J. Physiol. (Paris)77:373–375.
Segal, M., 1982a, Multiple actions of acetylcholine at a muscarinic receptor studied in the rat hippocampal slice, Brain Res. 246:77–87.
Segal, M., 1982b, Intracellular analysis of a postsynaptic action of adenosine in the rat hippocampus, Eur. J. Pharmacol. 79:193–199.
Segal, M., 1982c, Norepinephrine modulates reactivity of hippocampal cells to chemical stimulation in vitro, Exp Neurol. 77:86–93.
Segal, M., and Bloom, F. E., 1974a, The action of norepinephrine in the rat hippocampus. I. Iontophoretic studies, Brain Res. 72:79–97.
Segal, M., and Bloom, F. E., 1974b, The action of norepinephrine in the rat hippocampus. II. Activation of the input pathway, Brain Res. 72:99–114.
Segal, M., and Gutnick, M. J., 1980, Effects of serotonin on extracellular potassium concentration in the rat hippocampal slice, Brain Res. 195:389–401.
Segal, M., and Landis, S., 1974, Afferents to the hippocampus of the rat studied with the method of retrograde transport of horseradish peroxidase, Brain Res. 78:1–15.
Segal, M, Pickel, V., and Bloom, F. E., 1973, The projections of the nucleus locus coeruleus: An autoradiographic study, Life Sci. 13:817–821.
Segal, M., Greenberger, V., and Hofstein, R., 1981, Cyclic AMP-generating systems in rat hippocampal slices, Brain Res. 213:351–364.
Seifert, W., 1983, Neurobiology of the Hippocampus, Academic Press, New York
Seress, L., and Ribak, C. E., 1983, GABAergic cells in the dentate gyrus appear to be local circuit and projection neurons, Exp. Brain Res. 50:173–182.
Siggins, G .R., and Schubert, P., 1981, Adenosine depression of hippocampal neurons in vitro: An intracellular study of dose-dependent actions on synaptic and membrane potentials, Neurosci. Lett. 23:55–60.
Smith, C. M., 1974, Acetylcholine release from the cholinergic septo-hippocampal pathway, Life Sci. 14:2159–2166.
Snyder, S. H., 1981, Adenosine receptors and the actions of methylxanthines, Trends Neurosci. 4:242–244.
Somogyi, P., Nunzi, M. G., Gorio, A., and Smith, A. D., 1983a, A new type of specific interneuron in the monkey hippocampus forming synapses exclusively with the axon initial segments of pyramidal cells, Brain Res. 259:137–142.
Somogyi, P., Smith, A. D., Nunzi, M. G., Gorio, A., Takagi, H., and Wu, J. Y., 1983b, Glutamate decarboxylase immunoreactivity in the hippocampus of the cat: Distribution of immunoreactive synaptic terminals with special reference to the axon initial segment of pyramidal neurons, J. Neurosci. 3:1450–1468.
Spencer, W. A., and Kandel, E. R., 1961a, Electrophysiology of hippocampal neurons. III. Firing level and time constant, J. Neurophysiol. 24:260–271.
Spencer, W. A., and Kandel, E. R., 1961b, Electrophysiology of hippocampal neurons. IV. Fast prepotentials, J. Neurophysiol. 24:272–285.
Spencer, W. A., and Kandel, E. R., 1961c, Hippocampal neuron responses to selective activation of recurrent collaterals of hippocampofugal axons, Exp. Neurol. 4:149–161.
Spencer, W. A., and Kandel, E. R., 1968, Cellular and integrative properties of the hippocampal pyramidal cell and the comparative electrophysiology of cortical neuron, Int. J. Neurol. 6:266–296.
Squire, L. R., 1982, The neuropsychology of human memory, Annu. Rev. Neurosci. 5:241–273.
Stafstrom, C. E., Schwindt, P. C., and Crill, W. E., 1982, Negative slope conductance due to a persistent subthreshold sodium current in cat neocortical neurons in vitro, Brain Res. 236:221–226.
Stanley, J. C., DeFrance, J. F., and Marchand, J. F., 1979, Tetanic and posttetanic potentiation in the septohippocampal pathway, Exp. Neurol. 64:445–451.
Stanton, P. K., and Sarvey, J. M., 1983, Blockade of long-term potentiation in rat hippocampal CA1 region by the protein synthesis inhibitors emetine and cycloheximide, Soc. Neurosci. Abstr. 9:678.
Steinbusch, H. W. M., 1981, Distribution of serotonin-immunoreactivity in the central nervous system of the rat—cell bodies and terminals, Neuroscience 6:557–618.
Stengaard-Pedersen, K., Fredens, K., and Larsson, L.-I., 1981, Enkephalin and zinc in the hippocampal mossy fiber system, Brain Res. 212:230–233.
Steward, O., 1976a, Topographic organization of the projections from the entorhinal area to the hippocampal formation of the rat, J. Comp. Neurol. 167:285–314.
Steward, O., 1976b, Reinnervation of dentate gyrus by homologous afferents following entorhinal cortical lesions in adult rats, Science 194:426–428.
Steward, O., and Brassel, S., 1983, Intrahippocampal injections of cycloheximide reversibly block long term potentiation, Soc. Neurosci. Abstr. 9:860.
Steward, O., White, W. F., Cotman, C. W., and Lynch, G., 1976, Potentiation of excitatory synaptic transmission in the normal and in the reinnervated dentate gyrus of the rat, Exp. Brain Res. 26:423–441.
Steward, O., White, W. F., and Cotman, C. W., 1977, Potentiation of the excitatory synaptic action of commissural, associational and entorhinal afferents to dentate granule cells, Brain Res. 134:551–560.
Storm-Mathisen, J., 1972, Glutamate decarboxylase in the rat hippocampal region after lesions of the afferent fibre systems: Evidence that enzyme is localized in intrinsic neurons, Brain Res. 40:215–235.
Storm-Mathisen, J., 1977, Localization of transmitter candidates in the brain: The hippocampal formation as a model, Prog. Neurobiol. 8:119–181.
Storm-Mathisen, J., and Fonnum, F., 1971, Quantitative histochemistry of glutamate decarboxylase in rat hippocampal region, J. Neurochem. 18:1105–1111.
Struble, R. B., Desmond, N. L., and Levy, W. B., 1978, Anatomical evidence for interlamellar inhibition in the fascia dentata, Brain Res. 152:580–585.
Swanson, L. W., and Hartman, B. K., 1975, The central adrenergic system: An immunofluorescence study of the location of cell bodies and their efferent connections in the rat utilizing dopamine-beta-hydroxylase as a marker, J. Comp. Neurol. 163:467–506.
Swanson, L. W., Teyler, T. J., and Thompson, R. F. (eds.), 1982, Hippocampal long-term potentiation: Mechanisms and implications for memory, Neurosci. Res. Progr. Bull. 20
Taylor, C. P., and Dudek, F. E., 1982a, A physiological test for electrotonic coupling between CA1 pyramidal cells in rat hippocampal slices, Brain Res. 235:351–357.
Taylor, C. P., and Dudek, E. E., 1982b, Synchronous neural afterdischarges in rat hippocampal slices without active chemical synapses, Science 218:810–812.
Taylor, D., Freedman, R., Seiger, Å, Olson, L., and Hoffer, B., 1980, Conditions for adrenergic hyperinnervation in hippocampus. II. Electrophysiological evidence from intraocular double grafts, Exp. Brain Res. 39:289–299.
Teyler, T. J., and Alger, B. E., 1976, Monosynaptic habituation in the vertebrate forebrain: The dentate gyrus examined in vitro, Brain Res. 115:413–425.
Thalmann, R. H., and Ayala, G. F., 1982, A late increase in potassium conductance follows synaptic stimulation of granule neurons of the dentate gyrus, Neurosci. Lett. 29:243–248.
Thalmann, R. H., Peck, E. J., and Ayala, G. F., 1981, Biphasic response of hippocampal pyramidal neurons to GABA, Neurosci. Lett. 21:319–324.
Thompson, R. F., Berger, T. W., Berry, S. D., Hoehler, F.K., Kettner, R. E., and Weisz, D. J., 1980, Hippocampal substrate of classical conditioning, Physiol. Psychol. 8:262–279.
Traub, R. D., 1983, Cellular mechanisms underlying the inhibitory surround of penicillin epileptogenic foci, Brain Res. 261:277–284.
Traub, R. D., and Llinás, R., 1979, Hippocampal pyramidal cells: Significance of dendritic ionic conductances for neuronal function and epileptogenesis, J. Neurophysiol. 42476–496
Traub, R. D., and Wong, R. K. S., 1981, Penicillin-induced epileptiform activity in the hippocampal slice: A model of synchronization of CA3 pyramidal cell bursting, Neuroscience 6:223–230.
Traub, R. D., and Wong, R. K. S., 1983a, Synaptic mechanisms underlying interictal spike initiation in a hippocampal network, Neurology 33:257–266.
Traub, R. D., and Wong, R. K. S., 1983b, Synchronized burst discharge in disinhibited hippocampal slice. II. Model of cellular mechanism, J. Neurophysiol. 49:459–471.
Turner, D. A., and Schwartzkroin, P. A., 1980, Steady-state electrotonic analysis of intracellularly stained hippocampal neurons, J. Neurophysiol. 44:184–199.
Turner, D. A., and Schwartzkroin, P. A., 1983, Electrical characteristics of dendrites and dendritic spines in intracellularly stained CA3 and dentate hippocampal neurons, J. Neurosci. 3:2381–2394.
Turner, R. W., Baimbridge, K. G., and Miller, J. J., 1982, Calcium-induced long-term potentiation in the hippocampus, Neuroscience 7:1411–1416.
Turner, R. W., Richardson, T. L., and Miller, J. J., 1983, Role of ephaptic interactions in paired pulse and frequency potentiation of hippocampal field potentials, Soc. Neurosci. Abstr. 9:733.
Turner, R. W., Richardson, T.L., and Miller J. J., 1984, Ephaptic interactions contribute to paired pulse and frequency potentiation of hippocampal field potentials, Exp. Brain Res. 59:567–570.
Valentino, R. J., and Dingledine, R., 1981, Presynaptic inhibitory effect of acetylcholine in the hippocampus, J. Neurosci. 1:784–792.
Vanderwolf, C. H., Kramis, R., Gillespie, L. A., and Bland, B. H., 1975, Hippocampal slow activity and neocortical low voltage fast activity: Relations to behavior, in: The Hippocampus Vol. 2 (R. L. Isaacson and K. H. Pribram, eds.), Plenum Press, New York, pp. 101–128
Vickery, B. G., Schmechel, D. E., and Haring, J. H., 1983, Study of GABAergic non-pyramidal neurons in plexiform layers and deep white matter of rat hippocampus, Soc. Neurosci. Abstr. 9:408.
Voronin, L. L., 1983, Long-term potentiation in the hippocampus, Neuroscience 10:1051–1069.
Watanabe, T., Taguchi, Y., Hayashi, H., Tanaka, J., Shiosaka, S., Tohyama, M., Kubota, H., Terano, Y., and Wada, H., 1983, Evidence for the presence of a histaminergic neuron system in the rat brain: An immunohistochemical analysis, Neurosci. Lett. 39:249–254.
Watkins, J. C., and Evans, R. H., 1981, Excitatory amino acid transmitters, Annu. Rev. Pharmacol. Toxicol. 21:165–204.
Westrum, L. E., and Blackstad, T. W., 1962, An electron microscopic study of the stratum radiatum of the rat hippocampus (regio superior, CA1) with particular emphasis on synaptology, J. Comp, Neurol. 119:281–309.
White, W. F., Nadler, J. V., and Cotman, C. W., 1979, The effect of acidic amino acid antagonists on synaptic transmission in the hippocampal formation in vitro, Brain Res. 164:177–194.
Wieraszko, A., and Lynch, G., 1979, Stimulation-dependent release of possible transmitter substances from hippocampal slices studied with localized perfusion, Brain Res. 160:372–376.
Wigström, H., and Gustafsson, B., 1981, Increased excitability of hippocampal unmyelinated fibres following conditioning stimulation, Brain Res. 229:507–513.
Wigström, H., Swann, J. W., and Andersen, P., 1979, Calcium dependency of synaptic long-lasting potentiation in the hippocampal slice, Acta Physiol. Scand. 105:126–128.
Wilson, R. C., Levy, W. B., and Steward, O., 1981, Changes in translation of synaptic excitation to dentate granule cell discharge accompanying long-term potentiation. II. An evaluation of mechanisms utilizing dentate gyrus dually innervated by surviving ipsilateral and sprouted crossed temporodentate inputs, J. Neurophysiol. 46:339–355.
Wimer, R. E., Norman, R., and Eleftheriou, B. E., 1973, Serotonin levels in hippocampus: Striking variations associated with mouse strain and treatment, Brain Res. 63:397–401.
Winson, J., 1974, Patterns of hippocampal theta rhythm in the freely moving rat, Electroencephalogr. Clin. Neurophysiol. 36:291–301.
Winson, J., 1980, Raphe influences on neuronal transmission from perforant pathway through dentate gyrus, J. Neurophysiol. 44:937–950.
Wong, R. K. S., and Clark, R. B., 1983, Single K+ channel currents from hippocampal pyramidal cells of adult guinea pig, Soc. Neurosci. Abstr. 9:602.
Wong, R. K. S., and Prince, D. A., 1978, Participation of calcium spikes during intrinsic burst firing in hippocampal neurons, Brain Res. 159:385–390.
Wong, R. K. S., and Prince, D. A., 1979, Dendritic mechanisms underlying penicillin-induced epileptiform activity, Science 204:1228–1231.
Wong, R. K. S., and Prince, D. A., 1981, Afterpotential generation in hippocampal pyramidal cells, J. Neurophysiol. 45:86–97.
Wong, R. K. S., and Schwartzkroin, P. A., 1982, Pacemaker neurons in the mammalian brain: Mechanisms and function, in: Cellular Pacemakers, Mechanisms of Pacemaker Generation Vol. 1 (D. O. Carpenter, ed.), Wiley, New York, pp. 237–254
Wong, R. K. S., and Traub, R. D., 1983, Synchronized burst discharge in disinhibited hippocampal slice. I. Initiation in CA2—CA3 region, J. Neurophysiol. 49:442–458.
Wong, R. K. S., Prince, D. A., and Basbaum, A. I., 1979, Intradendritic recordings from hippocampal neurons, Proc. Natl. Acad. Sci. USA 76:986–990.
Wong, R. K. S., Traub, R. D., and Miles, R., 1984, Epileptogenic mechanisms as revealed by studies of the hippocampal slice, in: Electrophysiology of Epilepsy (P. A. Schwartzkroin and H. V. Wheal, eds.), Academic Press, New York, pp. 253–275
Woodward, D. J., Moises, H. C., Waterhouse, B. D., Hoffer, B. J., and Freedman, R., 1979, Modulatory actions of norepinephrine in the central nervous system, Fed. Proc. 38:2109–2116.
Yaari, Y., Konnerth, A., and Heinemann, U., 1983, Spontaneous epileptiform activity of CA1 hipocampal neurons in low extracellular calcium solutions, Exp. Brain Res. 51:153–156.
Yamamoto, C., 1972, Activation of hippocampal neurons by mossy fiber stimulation in thin brain sections in vitro, Exp. Brain Res. 14:423–435.
Yamamoto, C., and Chujo, T., 1978, Long-term potentiation in thin hippocampal sections studied by intracellular and extracellular recordings, Exp. Neurol. 58:242–250.
Yamamoto, C., and Kawai, N., 1967, Presynaptic action of acetylcholine in thin sections from the guinea pig dentate gyrus in vitro, Exp. Neurol. 19:176–187.
Yamamoto, C., Matsumoto, K., and Takagi, M., 1980, Potentiation of excitatory postsynaptic potentials during and after repetitive stimulation in thin hippocampal sections, Exp. Brain Res. 38:469–477.
Yamamoto, C., Sawada, S., and Takada, S., 1983, Suppressing action of 2-amino-4-phosphonobutyric acid on mossy fiber-induced excitation in the guinea pig hippocampus, Exp. Brain Res. 51:128–134.
Young, W. S., and Kuhar, M. J., 1980, Noradrenergic alpha-1 and alpha-2 receptors: Light microscopic autoradiographic localization, Fed. Proc. 39:593.
Zieglgänsberger, W., French, E., Siggins, G., and Bloom, F., 1979, Opioid peptides may excite hippocampal pyramidal neurons by inhibiting adjacent inhibitory interneurons, Science 205:415–417.
Zimmer, J., 1971, Ipsilateral afferents to the commissural zone of the fascia dentata demonstrated in decommissurated rats by silver impregnation, J. Comp. Neurol. 142:393–416.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1987 Plenum Press, New York
About this chapter
Cite this chapter
Schwartzkroin, P.A., Mueller, A.L. (1987). Electrophysiology of Hippocampal Neurons. In: Jones, E.G., Peters, A. (eds) Cerebral Cortex. Cerebral Cortex, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6616-8_8
Download citation
DOI: https://doi.org/10.1007/978-1-4615-6616-8_8
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4615-6618-2
Online ISBN: 978-1-4615-6616-8
eBook Packages: Springer Book Archive