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Abstract

The perception of radiation hazards in society must be completely re-evaluated as a result of the recent realization that radon represents the largest source of natural background radiation to the U.S. population (1). Studies designed to identify a link between lung cancer and radon in the home, by seeking a correlation between lung cancer incidence and variations in regional radon levels, have produced results that are equivocal. In epidemiological studies, uraninum miners exposed for many years to high radon levels in the mines show an enhanced incidence of lung cancer (2–4). The perceived risk to the public from breathing lower levels of radon in the home are based on an extrapolation from the high concentrations experienced by the miners. However, extrapolating from the uranium miner data involves complications because most miners studied were also heavy cigarette smokers. The number of non-smoking miners is too small to separate the effects of radon from those of the cigarette smoke.

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References

  1. NCRP Report No. 78, Evaluation of occupational and environmental exposures to radon and radon daughters in the U. S. National Council on Radiation Protection and Measurements, Washington, D.C., 1984.

    Google Scholar 

  2. W. J. Bair, Inhalation of radionuclides and carcinogenesis. In: Inhalation Carcinogenesis (M.G. Hanna, P. Netteshelm and J.R. Gilbert, Eds.), pp. 77–97. U.S. Atomic Energy Commission, Washington, D.C., 1970.

    Google Scholar 

  3. F. E. Lundin, J. W. Lloyd, E. M. Smith, V. E. Archer and D. A. Holaday, Mortality of uranium miners In relation to radiation exposure, hard-rock mining and cigarette smoking, 1950 through September 1967. Health Phys. 16, 571–578 (1969).

    Article  PubMed  Google Scholar 

  4. A. S. Whlttemore and A. McMillan, Lung cancer mortality among U.S. uranium miners; A reappraisal. J. Natl. Cancer. Inst. 71, 489–493 (1983).

    Google Scholar 

  5. C. A. Reznlkoff, J. S. Bertram, D. W. Brankow and C. Heldelberger, Quantitative and qualitative studies on chemical transformation of cloned C3H mouse embryo cells sensitive to post confluence inhibition of cell division. Cancer Res. 33, 3239–3249 (1973).

    Google Scholar 

  6. T. K. Hel, E. J. Hall and R. Osmak, Asbestos, radiation and oncogenic transformation. J. Cancer 50, 717–720 (1984).

    Article  Google Scholar 

  7. T. K. Hel, C. R. Geard, R.S. Osmak and M. Travlsano, Correlation of in vitro genotoxicity and oncogenicity induced by radiation and asbestos fibers. J. Cancer 52 591–597 (1985).

    Article  Google Scholar 

  8. R. P. Bird, N. Rohrlg, R. D. Colvett, C. R. Geard and S. A Marino, Inactivation of synchronized Chinese hamster V79 cells with charged particles track segments. Radiat. Res. 82, 277–289 (1980).

    Article  PubMed  CAS  Google Scholar 

  9. E. L. Lloyd, M. A. Glemmell, C. B. Hennlng, D. S. Giemmell and B. J. Zabransky, Cell survival following multiple track alpha particle irradiation. Int. J. Radiat. Biol. 35, 23–31 (1979).

    Article  CAS  Google Scholar 

  10. C. R. Geard and T. Harding, Morphometric studies with attached mouse C3H 10T1/2 cells. In: Radiation Physcls, Biophysics and Radiation Biology. U.S. DOE Progress Report, 1982. Columbia University, pp. 274–280.

    Google Scholar 

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© 1987 Plenum Press, New York

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Hall, E.J., Hei, T.K., Randers-Pehrson, G. (1987). Radon-Induced Transformation. In: Cerutti, P.A., Nygaard, O.F., Simic, M.G. (eds) Anticarcinogenesis and Radiation Protection. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6462-1_49

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  • DOI: https://doi.org/10.1007/978-1-4615-6462-1_49

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-6464-5

  • Online ISBN: 978-1-4615-6462-1

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