Abstract
Bone marrow transplantation (BMT) from HLA-identical sibling donors has been successfully utilized in the treatment of high-risk or recurrent hematological malignancies, bone marrow failure syndromes, and selected hereditary immunodeficiency states and metabolic disorders. Use of allogeneic BMT has been limited both by the lack of suitable donors and because of the risk of life-threatening complications that arise when donor and recipient are not immunologically identical, namely, graft failure and graft-versus-host disease (GVHD).
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Wagner, J.E. (1997). Allogeneic umbilical cord blood transplantation. In: Winter, J.N. (eds) Blood Stem Cell Transplantation. Cancer Treatment and Research, vol 77. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6349-5_9
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