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Lesion Morphology and Composition: Risk of Restenosis Following Coronary Interventions

  • Chapter
Coronary Stenosis Morphology: Analysis and Implication

Abstract

In the past 10 years, there has been significant progress in our understanding of the clinical problem of restenosis following balloon angioplasty. This is due to a combined approach to determine the pathophysiology and complex biologic mechanisms that contribute to restenosis and the introduction and use of measurement systems in documenting and assessing the process. It should be recalled that in the early angioplasty years (1980-1985), angiographic assessment of restenosis was entirely on a categorical basis, the value of angiographic follow-up questionnable and clinical cardiologists were largely unaware of the use of quantitative angiography. Although quantitative coronary angiography (QCA) has been predominantly a research tool in interventional cardiology, it has raised the standards of interventional practice from purely “an art” to a more scientific level that can be evaluated by evidence-based medicine. QCA has altered our perceptions of restenosis and has served as the gold standard for comparing restenosis therapies (drugs and devices).

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References

  1. Ryan T, Faxon DP, Gunnar RM, et al. Guidelines for percutaneous transluminal coronary angioplasty: A report of the American College of Cardiology/American Heart Association Task Force on assessment of diagnostic and therapeutic cardiovascular procedures. J Am Coil Cardiol 1988; 12:529–546

    Article  Google Scholar 

  2. Ellis SG, Vandormael MG, Cowley MJ, et al. Coronary morphologic and clinical determinants of procedural outcome with angioplasty for multivessel coronary disease. Implications for patient selection. Circulation 1990; 82:1193–1202

    Article  PubMed  CAS  Google Scholar 

  3. Gruentzig AR, Senning A, Siegenthaler We. Non-operative dilatation of coronary artery stenosis: Percutaneous transluminal coronary angioplasty. N Engl J Med 1979; 301:61–68

    Article  Google Scholar 

  4. Mancini GBJ. Quantitative coronary arteriographic methods in the interventional catheterization laboratory: an update and perspective. J Am Coll Cardiol 1991; 17:23B–33B

    Article  PubMed  CAS  Google Scholar 

  5. Zir LM, Miller SW, Dinsmore RE, et al. Interobserver variability in coronary angiography. Circulation 1976; 627–632

    Google Scholar 

  6. Goldberg RK, Kleiman NS, Monor ST, AbukhaJil J, Raizner AE. Comparison of quantitative coronary angiography to visual estimates of lesion severity pre and post PTCA. Am Heart J 1990; 1:178–184

    Article  Google Scholar 

  7. Keane D, Haase J, Slager C, Montauban van Swijndregt E, Lehmann K, Ozaki Y, Di Mario C, Kirkeeide R, Serruys PW. Comparative validation of quantitative coronary angiography systems: results and implications from a multicenter study using a standarized approach. Circulation 1995; 91:2174–2183

    Article  PubMed  CAS  Google Scholar 

  8. Leimgruber PP, Roubin GS, Anderson HV, et al. Influence of intimai dissection on restenosis after successful coronary angioplasty. Circulation 1985; 72:530–35

    Article  PubMed  CAS  Google Scholar 

  9. Holmes DR, Vlietstra RE, Smith HC, et al. Restenosis after percutaneous transluminal coronary angioplasty (PTCA): a report from the angioplasty registry of the National Heart Lung and Blood Institute. Am J Cardiol 1984; 53:77C–81C

    Article  PubMed  Google Scholar 

  10. Gould KL, Lipscomb K. Effects of coronary stenoses on coronary flow reserve and resistance. Am J Cardiol 1974; 33:87–94

    Article  PubMed  CAS  Google Scholar 

  11. Gould KL, Kelley KO, Bolson EL Experimental validation of quantitative coronary adenography for determining pressure-flow characteristics of coronary stenosis. Circulation 1982; 66:930–937

    Article  PubMed  CAS  Google Scholar 

  12. Rensing BJ, Hermans WRM, Deckers JW, de Feyter PJ, Tijssen JGP, Serruys PW. Luminal narrowing after percutaneous transluminal coronary balloon angioplasty follows a near Gaussian distribution. A quantitative angiographic study in 1445 successfully dilated lesions. J Am Coll Cardiol 1992; 19:939–945

    Article  PubMed  CAS  Google Scholar 

  13. Kuntz RE, Safian RD, Levine MJ, Reis GJ, Diver DJ, Bairn DS. Novel approach to the analysis of restenosis after the use of three new coronary devices. J Am Coll Cardiol 1992; 19:1493–1500

    Article  PubMed  CAS  Google Scholar 

  14. Lehmann KG, Melkert R, Serruys PW. Contributions of frequence distribution analysis to the understanding of coronary restenosis. A reappraisal of the Gaussian Curve. Circulation 1996; 93:1123–1132

    Article  PubMed  CAS  Google Scholar 

  15. King SB III, Weintraub WS, Tao X, Hearn J, Couglas JS Jr. Bimodal distribution of diameter stenosis 4 to 12 months after angioplasty: implications for definitions and interpretation of restenosis. J Am Coll Cardiol 1991; 17:345A (abstract)

    Google Scholar 

  16. Beatt KJ, Serruys PW, Luijten HE, Rensing B, Suryapranata H, de Feyter P, van den Brand M, Laarman GJ, Roelandt J. Restenosis after coronary angioplasty: The paradox of increased lument diameter and restenosis. J Am Coll Cardiol 1992; 19:258–266

    Article  PubMed  CAS  Google Scholar 

  17. Kuntz RE, Safian RD, Carroza JP, Fischman RF, Mansour M, Bairn Ds. The importance of acute luminal diameter in determining restenosis after coronary atherectomy or stenting. Circulation 1992; 86:1827–35

    Article  PubMed  CAS  Google Scholar 

  18. Serruys PW, Umans VAWM, Strauss BH, van Suylen RJ, de Feyter PJ. Quantitative angiography after directional coronary atherectomy. Br Heart J 1991; 66:122–129

    Article  PubMed  CAS  Google Scholar 

  19. Umans VAWM, Robert A, Foley D, Wijns W, Haine E, de Feyter P, Serruys PW. Clinical, histologic and quantitative angiographic predictors of restenosis following directional coronary atherectomy: a multivariate analysis of the renarrowing process and late outcome. J Am Coll Cardiol 1994; 23:49–59

    Article  PubMed  CAS  Google Scholar 

  20. Strauss BH, Serruys PW, Bertrand ME, et al. Quantitative angiographic follow-up of th ecoronary Wallstent in native vessels and bypass graft (European experience-March 1986-March 1990). Am J Cardiol 1992; 69:475–81

    Article  PubMed  CAS  Google Scholar 

  21. Serruys PW, de Jaegere P, Kiemeneij F, et al. A comparison of balloon expandable-stent implantation with balloon angioplasty in patients with coronary artery disease. N Engl J Med 1994; 331:489–495

    Article  PubMed  CAS  Google Scholar 

  22. Fishman DL, Leon MB, Bairn DS, et al. A randomized comparison of coronary stent placement and balloon angioplasty in the treatment of coronary artery disease. N Engl J Med 1994; 331:496–501

    Article  Google Scholar 

  23. Topol EJ, Leya F, Pinkerton CA, et al. A comparison of directional atherectomy with coronary angioplasty in patients with coronary artery disease. N Engl J Med 1993; 329:221–227

    Article  PubMed  CAS  Google Scholar 

  24. Adelman AG, Cohen EA, Kimball BP, et al. A comparison of directional atherectomy with balloon angioplasty for lesions of the left anterior descending artery. N Engl J Med 1993; 329:228–233

    Article  PubMed  CAS  Google Scholar 

  25. Kuntz RE, Gibson CM, Nobuyoshi M, Bairn Ds. Generalized model of restenosis after conventional balloon angioplasty, stenting and DCA. J Am Coll Cardiol 1993; 21:15–25

    Article  PubMed  CAS  Google Scholar 

  26. Bittl JA, Kuntz RE, Estella P, Sanbom TA, Bairn DS. Analysis of late lumen narrowing after excimer laser-facilitated coronary angioplasty. J Am Coll Cardiol 1994; 23:1314–20

    Article  PubMed  CAS  Google Scholar 

  27. Kuntz RE, Bairn DS. Defining coronary restenosis. Newer clinical and angiographic paradigms. Circulation 1993; 88:1310–1323

    Article  PubMed  CAS  Google Scholar 

  28. Foley DP, Appelman YE, Strikwerda S, Piek JJ, Koolen JJ, Tijssen JP, de Feyter PJ, David QK, van Swijndregt EJ, Melkert R, Serruys PW. A comparison of angiographic restenosis propensity of excimer laser coronary angioplasty and balloon angioplasty in longer coronary lesions. In: Short and long-term results of tnansluminal coronary interventions: an angiographic perspective. Foley DP (PhD thesis). Erasmus University, Rotterdam 1995

    Google Scholar 

  29. Appelman YEA, Piek JJ, Strikwerda S, Tijssen JGP, de Feyter PJ, David GK, Serruys PW, Margolis JR, Koelemay MJ, Montauban van Swijndregt EWJ, Koolen JJ. Lancet 1996; 34779–84

    Google Scholar 

  30. Rensing BJ, Hermans WRM, Deckers JW, de Feyter PJ, Serruys PW. Which angiographic parameter best describes functional status 6 months after successful single vessel coronary balloon angioplasty?. In: Restenosis after percutaneous transluminal coronary angioplasty. A Quantitative angiographic approach. Rensing BJWM (PhD Thesis). Erasmus Univeristy, Rotterdam 1992.

    Google Scholar 

  31. Keane D, Melkert R, Herrman JP, Foley DP, Ozaki Y, Di Mario C, de Feyter PJ, Serruys PW. Quantitative coronary angiography endpoints: a valid surrogacy for clinical events? In: de Feyter PJ, Di Mario C and Serruys PW (eds). Quantitative Coronary Imaging. Barjesteh, Meeuwes & Co., Rotterdam 1995

    Google Scholar 

  32. Keane D, Serruys PW. Quantitative coronary angiography: an integral component of interventional cardiology. In: Topol EJ, Serruys PW (eds). Current Review Of Interventionsl Cardiology, 2nd edition. Current Medicine, Philadelphia, 1995:205–233

    Google Scholar 

  33. Post MJ, Borst C, Kuntz RE. The relative importance of arterial remodeling compared with intimal hyperplasia in lumen renarrowing after balloon angioplasty: a study in the normal rabbit and the hypercholesterolemic Yucatan micropig. Circulation 1994; 89:2816–2821

    Article  PubMed  CAS  Google Scholar 

  34. Kakuta T, Currier JW, Haudenschild CC, Ryan TH, Faxon DP. Differences in compensatory vessel enlargement, not intimal formation, account for restenosis after angioplasty in the hypercholesterolemic rabbit model. Circulation 1994; 89:2809–2815

    Article  PubMed  CAS  Google Scholar 

  35. Isner J. Vascular remodeling. Honey, I think I shrunk the artery. Circulation 1994; 89:2937–2941

    Article  PubMed  CAS  Google Scholar 

  36. Kimura T, Kaburagi S, Tashima Y, Nobuyoshi M, Mintz GS, Popma JJ. Geometric remodeling and intimal regrowth as mechanisms of restenosis: observations from serial ultrasound analysis of restenosis (SURE) trial. Circulation 1995; 92[suppl 1]:1–76 (abstract)

    Google Scholar 

  37. Mintz GS, Kent KM, Satier LF, Wong SC, Hong MK, Griffin J, Pichard AD. Dimorphic mechanisms of restenosis after DCA and stents: A serial intravascular ultrasound study. Circulation 1995; 92[suppl 1]:1–546 (abstract)

    Google Scholar 

  38. Umans VA, Robert A, Foley DP, Haine E, de Feyter PJ, Wijns W, Serruys PW. Clinical, angiographic and histologic predictors of restenosis after directional coronary atherectomy: a multivariate analysis of the renarrowing process and late outcome. J Am Coll Cardiol 1994; 23:49–59

    Article  PubMed  CAS  Google Scholar 

  39. Beatt KJ, Serruys PW, Hugenholtz PG. Restenosis after coronary angioplasty: new standards for clinical studies. J Am Coll Cardiol 1990; 15:491–498

    Article  PubMed  CAS  Google Scholar 

  40. Ozaki Y, Keane D, Di Mario C, Camenzid E, Baptista J, de Feyter P, Roelandt JRTC, Serruys PW. Comparison of coronary luminal quantification obtained from both geometric and videdensitometric quantitative angiography and from intracoronary ultrasound pre and post coronary intervention. Submitted

    Google Scholar 

  41. Gorge G, Liu F, Ge J, Haude M, Baumgart D, Caspary G. Intravascular ultrasound variables predict restenosis after PTCA. Circulation 1995; 92[suppl 1]:1–148 (abstract)

    Google Scholar 

  42. Umans VA, Strauss BH, de Feyter PJ, Serruys PW. Edge detection versus videodensitometry for quantitative angiographic assessment of directional coronary atherectomy. Am J Cardiol 1991; 68:534–538

    Article  PubMed  CAS  Google Scholar 

  43. Serruys PW, Strauss BH, Beatt KJ, Bertrand M, Puel J, Rickards AF, Kappenberger L, Meier B, Goy JJ, Vogt P, Sigwart U. Angiographic follow-up after placement of a self-expanding coronary stent. N Engl J Med 1991; 324:13–17.

    Article  PubMed  CAS  Google Scholar 

  44. Strauss BH, Juilliere Y, Rensing BJ, Reiber JHC, Serruys PW. Edge detection versus densitometry for assessing coronary stenting quantitatively. Am J Cardiol 1991; 67:484–490

    Article  PubMed  CAS  Google Scholar 

  45. Blasini R, Schuhlen H, Mudra H, et al. Angiographic overestimation of lumen size after coronary stent placement: Impact of high pressure dilatation. Circulation 1995; 92[suppl 1]:1–223 (abstract)

    Google Scholar 

  46. Penny WF, Schmidt Da, Safian RD, Emy RE, Bairn DS. Insights into the mechanism of luminal improvement after directional coronary atherectomyl. Am J Cardiol 1991; 67:435–437

    Article  PubMed  CAS  Google Scholar 

  47. Umans VA, Baptista J, Di Mario C, von Birgelen C, de Jaegere P, de Feyter PJ, Serruys PW. Angiographic, ultrasonic and angioscopic assessment of the coronary artery wall and lumen area configuration after directional atherectomy: The mechanism revisited. Am Heart J 1995; 130:217–27

    Article  PubMed  CAS  Google Scholar 

  48. Umans VA, Haine E, Renkin J, De Feyter PJ, Wijns W, Serruys PW. The mechanism of directional coronary atherectomy. Eur Heart J 1993; 14:505–510

    Article  PubMed  CAS  Google Scholar 

  49. Strauss BH, Escaned J, Foley DP, Di Mario C, Haase J, Keane D, Hermans WRM, de Feyter PJ, Serruys PW. Technological considerations and practical limitations in the use of quantitative angiography during percutaneous coronary recanalization. Prog Cardiovasc Dis 1994; 36:343–362

    Article  PubMed  CAS  Google Scholar 

  50. Foley DP, Escaned J, Strauss BH, di Mario C, Haase J, Keane D, Umans VA, Hermans WR, Rensing BJ, de Feyter PJ, Serruys PW. Quantitative coronary angiography (OCA) in interventional cardiology: Application to scientific research and clinical practice. Prog Cardiovasc Dis 1994; 36:363–384

    Article  PubMed  CAS  Google Scholar 

  51. Foley DP, Melkert R, Serruys PW. Influence of coronary vessel size on renarrowing process and late angiographic outcome after successful balloon angioplasty. Circulation 1994; 90:1239–1251

    Article  PubMed  CAS  Google Scholar 

  52. Azar AJ, Ketre K, Goldberg S, Kiemeneij F, Leon MB, Serruys PW. A meta analysis on the clinical and angiographic outcomes of stents vs PTCA in the different coronary vessel sizes in the Benestent-1 and Stress-1/2 Trials. Circulation 1995; suppl 1:1–475 [abstract]

    Google Scholar 

  53. Hall P, Nakamura S, Maiello L, Almagor Y, Gaglione A, Goldberg SL, Tobis JM, Martini, Tucct G, Di Maggio M, Colombo A. Clinical and angiographic outcome after PaJmaz-Schatz stent implantation guided by intravascular ultrasound. In: de Feyter PJ, Di Mario C and Serruys PW (eds). Quantitative Coronary Imaging. Barjesteh, Meeuwes & Co., Rotterdam 1995

    Google Scholar 

  54. Akira I, Hall P, Maiello L, Blengino S, Finci L, Ferraro M, Martini G, Colombo A. Coronary stenting of long lesions (greater than 20 mm)-A matched comparison of different stents. Circulation 1995; 92[suppl 1]:1–688 (abstract)

    Google Scholar 

  55. Guiteras Val PG, Bourassa MG, David PR, et al. Restenosis after successful percutaneous transluminal coronary angioplasty: the Montreal Heart Institute experience. Am J Cardiol 1987; 60:50B–55B

    PubMed  CAS  Google Scholar 

  56. Vandormael MG, Deligonul U, Kern M, et al. Multilesion coronary angioplasty: clinical and angiographic follow-up. J Am Coll Cardiol 1987; 10:246–252

    Article  PubMed  CAS  Google Scholar 

  57. Hirshfeld JW Jr, Schwartz JS, Jugo R, et al. Restenosis after coronary angioplasty: a multivariate statistical model to relate lesion and procedure variables to restenosis. J Am Coll Cardiol 1991; 18:647–56

    Article  PubMed  Google Scholar 

  58. Foley DP, Melkert R, Serruys PW. Restenosis after percutaneous intervention: is there a device specificity? Handbook of Interventionsl Cardiology. Topol E and Serruys PW (eds). In press.

    Google Scholar 

  59. Rensing BJ, Hermans WR, Vos J, et al. Luminal narrowing after percutaneous transluminal coronary angioplasty. A study of clinical, procedural, and lesional factors related to long-term angiographic outcome. Coronary Artery Restenosis Prevention on Repeated Thromboxane Antagonism (CARPORT) Study Group. Circulation 1993; 88:975–985.

    Article  PubMed  CAS  Google Scholar 

  60. Hermans WRM, Rensing BJ, Foley D, Tijssen JGP, Rutsch W, Emanuelsson H, Danchin N, Wijns W, Chappuis F, Serruys PW. Patient, lesion and procedural variables as risk factors for luminal re-narrowing after successful coronary angioplasty. A quantitative analysis in 653 patients with 778 lesions. J Cardiovasc Pharm 1993; 22:S45–S57

    Article  Google Scholar 

  61. Strauss BH, Serruys PW, de Scheerder IK, Tijssen JGP, Bertrand M, Puel J, Meier B, Kaufmann U, Stauffer JC, Rickards AF, Sigwart U. Relative risk analysis of angiographic predictors of restenosis in the coronary WallstentR. Circulation 1991; 84:1636–1643

    Article  PubMed  CAS  Google Scholar 

  62. Reimers B, di Mario C, Nierop P, Pasquetto G, Camenzind E, Ruygrok P. Long term restenosis after multiple stent implantation. A quantitative angiographic study. Circulation 1995; 92[supplement 1]:1–327 (abstract)

    Google Scholar 

  63. Schiele TM, Marx R, Vogt M, Leschke M, Heintzen MP. Eccentricity of coronary arteries is a predictor of chronic restenosis after directional atherectomy. Circulation 1995; 92[suppl 1]:1–328 (abstract)

    Google Scholar 

  64. Kimball BP, Cohen EA, Adelman AG. Influence of stenotic lesion morphology on immediate and long-term (6 months) angiographic outcome: comparative analysis of directional coronary atherectomy versus standard balloon angioplasty. J Am Coll Cardiol 1996; 27:543–551

    Article  PubMed  CAS  Google Scholar 

  65. Topol EJ, Ellis SG, Fishman J et al. Multicenter study of percutaneous transluminal angioplasty for right coronary ostial stenosis. J Am Coll Cardiol. 1987; 9:1214–1218

    Article  PubMed  CAS  Google Scholar 

  66. de Feyter PJ, van Suylen R-J, de Jaegere PPT, Topol EJ, Serruys PW. Balloon angioplasty for the treatment of lesions in saphenous vein bypass grafts. J Am Coll Cardiol 1993; 21:1639–49

    Google Scholar 

  67. Mathias DW, Mooney JF, Lange HW et al. Frequency of success and complications of coronary angioplasty of a stenosis at the ostium of a branch vessel. Am J Cardiol. 1991:67:491–495.

    Article  PubMed  CAS  Google Scholar 

  68. Popma JJ, Leon MB, Mintz GS, Kent KM, Satler LF, Garrand TJ, Pichard AD. Results of coronary angioplasty using the TEC catheter. Am J Cardiol. 1992:70:1526–1532

    Article  PubMed  CAS  Google Scholar 

  69. Sos TA, Saddekini S, Pickering TG, Laragh JH. Technical aspects of percutaneous transluminal angioplasty in renovascular disease. Nephron. 1986:supp11:45–50

    Google Scholar 

  70. Stewart J, Ward D, Davies M, Pepper J. Isolated coronary ostial stenosis: observations on pathology. Eur Heart J. 1987:8:917–920.

    PubMed  CAS  Google Scholar 

  71. Boehrer JD et al. Directional atherectomy versus balloon angioplasty for coronary ostial and nonostial left anterior descending coronary artery lesions: results from a randomized multicenter trial. J Am Coll Cardiol. 1995:25:1380–1386

    Article  PubMed  CAS  Google Scholar 

  72. Abdel-Meguid AE, Whitlow PL, Simpfebdorfer C, Sapp SK, Franco I, Ellis SG and Topol E. Percutaneous revascularization of ostial saphenous vein graft stenoses. J Am Coll Cardiol. 1995:26:955–960

    Article  PubMed  CAS  Google Scholar 

  73. Ghazzal ZYB, Burton E, Weintraub WS, Utvack F, Rothbaum DA, Klein L, King SB. Predictors of restenosis after excimer laser coronary angioplasty. Am J Cardiol. 1995:75:1012–1014

    Article  PubMed  CAS  Google Scholar 

  74. Strauss BH, Natarjan MK, Batchelor WB, Yardley DE, Sanbom TA, Power JA, Watson LE, Moothart R, Tcheng JE, Bittl JA, Chisholm RJ. Quantitative angiographic analysis of the vein graft lesions treated with excimer laser angioplasty: Immediate and follow-up results. Circulation 1995; 92:348–356

    Article  PubMed  CAS  Google Scholar 

  75. Colombo A, Itoh A, Maiello L Coronary stent implantation in aorto-ostiaJ lesions: immediate and follow-up results. J Am Coll Cardiol 1996; 27[suppl A]:253A

    Article  Google Scholar 

  76. Zampieri P, Colombo A, Almagor Y, Marello L, Finci L. Results of coronary stenting of ostial lesions. Am J Cardiol 1994; 73:901–903

    Article  PubMed  CAS  Google Scholar 

  77. Kaltenbach M, Kober G, Scherer D, Vallbracht C. Recurrence rate after successful coronary angioplasty. Eur Heart J 1985; 6:276–281

    PubMed  CAS  Google Scholar 

  78. DiSciascio G, Cowley MJ, Vetrovec GW. Angiographic patterns of restenosis after angioplasty of multiple coronary arteries. Am J Cardiol 1986; 58:922–925

    Article  PubMed  CAS  Google Scholar 

  79. Myler RK, Topol EJ, Shaw RE, et al. Multiple vessel coronary angioplasty in 494 consecutive patients. Cathet Cardiovasc Diagn 1987; 13:1–15

    Article  PubMed  CAS  Google Scholar 

  80. Black AJR, Anderson HV, Roubin GS, et al. Repeat coronary angioplasty: Correlates of a second restenosis. J Am Coll Cardiol 1988; 11714–718

    Google Scholar 

  81. Renkin J, Melin J, Robert A, et al. Detection of restenosis after successful coronary angioplasty: improved clinical decision making with use of a logistic model combining procedural and follow-up variables. J Am Coll Cardiol 1990; 16:1333–1340

    Article  PubMed  CAS  Google Scholar 

  82. Rupprecht HJ, Brennecke R, Bemhard G, Erbel R, Pop T, Meyer J. Analysis of risk factors for restenosis after PTCA. Cathet Cardiovasc Diagn 1990; 19:151–159

    Article  PubMed  CAS  Google Scholar 

  83. Leimgruber PP, Roubin GS, Hollman J et al. Restenosis after successful coronary angioplasty in patients with single-vessel disease. Circulation 1986; 73:710–717

    Article  PubMed  CAS  Google Scholar 

  84. de Feyter PJ, Suryapranata H, Serruys PW, et al. Coronary angioplasty for unstable angina: immediate and late results in 200 consecutive patients with identification of risk factors for unfavourable early and late outcome. J Am Coll Cardiol 1988; 12:324–333

    Article  PubMed  Google Scholar 

  85. Hermans WRM, Rensing BJ, Kelder JC, de Feyter PJ, Seruys PW. Postangioplasty restenosis rate between segments of the major coronary arteries. Am J Cardiol 1992; 69:194–200

    Article  PubMed  CAS  Google Scholar 

  86. Rensing BJ, Hermans WRM, Vos J, Tijssen JGP, Rutsch W, Danchin N, Heyndrickx GR, Mast EG, Wijns W, Serruys PW. Luminal narrowing after percutaneous transluminal coronary. A study of clinical, procedural and lesional factors related to long term angiographic outcome. In: Restenosis after percutaneous transluminal coronary angioplasty. A Quantitative angiographic approach. Rensing BJWM (PhD Thesis). Erasmus Univeristy 1992, Rotterdam.

    Google Scholar 

  87. Mintz GS, Popma JJ, Pichard AD, et al. Patterns of calcification in coronary artery disease.: A statistical analysis of intravascular ultrasound and coronary angiography in 1155 lesions. Circulation 1995,91:1959–1965

    Article  PubMed  CAS  Google Scholar 

  88. Ozaki Y, Keane D, Di Mario C, Camenzid E, Baptista J, de Feyter P, Roelandt JRTC, Serruys PW. Comparison of coronary luminal quantification obtained from both geometric and videdensitometric quantitative angiography and from intracoronary ultrasound pre and post coronary intervention. Submitted

    Google Scholar 

  89. Fitzgerald PJ, Ports TA, Yock PG. Contribution of localized calcium deposits to dissection after angioplasty in vivo assessed by intravascular ultrasound imaging. Circulation 1992; 86:64–70

    Article  PubMed  CAS  Google Scholar 

  90. Gil R, Di Mario C, Prati F, von Birgelen C, Ruygrok P, Roelandt JRTC, Serruys PW. Influence of plaque composition on mechanisms of percutaneous transluminal coronary balloon angioplasty assessed by ultrasound imaging. In: de Feyter PJ, Di Mario C and Serruys PW (eds). Quantitative Coronary Imaging. Barjesteh, Meeuwes & Co., Rotterdam 1995

    Google Scholar 

  91. Tenaglia AN, Buller C, Kisslo KB, et al. Mechanisms of balloon angioplasty and directional coronary atherectomy as assessed by intracoronary ultrasound. J Am Coll Cardiol 1992; 20:685–691

    Article  PubMed  CAS  Google Scholar 

  92. Botas J, Clark DA, Pinto F, et al. Balloon angioplasty results in increased segemental coronary distensibility: a likely mechanism of percutaneous transluminal coronary angioplasty. J Am Coll Cardiol 1994; 23:1043–1052

    Article  PubMed  CAS  Google Scholar 

  93. Matar FA, Mintz GS, Pinnow E, et al. Multivariate predictors of intravascular ultrasound endpoints after directional coronary atherectomy. J Am Coll Cardiol 1995; 25:318–324

    Article  PubMed  CAS  Google Scholar 

  94. Kovach J, Mintz GS, Javier S, et al. Mechanisms of lumen enlargement after excimer laser angioplasty and adjunct balloon angioplasty: a sequential intravascular ultrasound study. J Am Coll Cardiol 1994; 23:449A (abstract)

    Google Scholar 

  95. Gorge G, Liu F, Ge J, Haude M, Baumgart D, Caspary G. Intrvascular ultrasound variables predict restenosis after PTCA. Circulation 1995; 92[suppl 1]:1–148 (abstract)

    Google Scholar 

  96. Ramee SR, White CJ, Collins TJ, Mesa JE, Murgo JP. Percutaneous angioscopy during coronary angioplasty using a steerable microangioscope. J Am Coll Cardiol 1991; 17:100–5

    Article  PubMed  CAS  Google Scholar 

  97. Mizuno K, Satomura K, Miyamoto A, et al. Angioscopic evaluation of coronary artery thrombi in acute coronary syndromes. N Engl J Med 1992; 326:287–91

    Article  PubMed  CAS  Google Scholar 

  98. Den Heijer P, Foley D, Escaned J, et al. Angioscopic versus angiographic detection of intimal dissection and intracoronary thrombus. J Am Coll Cardiol 1994; 24:649–654

    Article  Google Scholar 

  99. Mizuno K, Miyamoto A, Isojima K, et al. A serial observation of coronary thrombi in vivo by a new percutaneous transluminal coronary angioscope. Angiology 1992; 43:91–99

    Article  PubMed  CAS  Google Scholar 

  100. Rensing BJ, Hermans WRM, Vos J et al Carport Group. Angiographic risk factors of luminaJ narrowing after coronary balloon angioplasty using balloon measurements to reflect stretch and elastic recoil at the dilatation site. Am J Cardiol 1992; 69:584–91

    Article  PubMed  CAS  Google Scholar 

  101. Di Mario C, The SHK, Madrestma S, et al. Detection and characterization of vascular lesions by intravascular ultrasound: an in vitro study correlated with histology. J Am Soc Echocardiogr 1992:5:135–46

    PubMed  Google Scholar 

  102. Gussenhoben EJ, Essed CE, Lancee CT, et al. Arterial wall characteristics determined by intravascular ultrasound imaging: an in vitro study. J Am Coll Cardiol 1989:14:947–52

    Article  Google Scholar 

  103. Peters RJG, PICTURE study group. Prediction of the risk of angiographic restenosis by intracoronary ultrasound imaging after coronary balloon angioplasty. J Am Coll Cardiol 1995; 25:35A (abstract)

    Article  Google Scholar 

  104. Mintz GS, Chuang YC, Popma JJ, et al. The final % cross-sectional narrowing (residual plaque burden) is the strongest intravascular ultrasound predictor of angiographic restenosis. J Am Coll Cardiol 1995; 25:35A (abstract)

    Article  Google Scholar 

  105. GUIDE Trial Investigators. Discrepancies between angiographic and intravascular ultrasound appearance of coronary lesions undergoing interventions. J Am Coll Cardiol 1993; 21:118A

    Google Scholar 

  106. Athanasiadis A, Schmid KM, Wullen B, Haase KK, Voelker W. Is the incidence of severe dissections predictable by pre-interventional intravascular ultrasound lesion morphology? Circulation 1995; 92[suppl 1]:1–148 (abstract)

    Google Scholar 

  107. Detre K, et al. Percutaneous transluminal coronary angioplasty in 1985-86 and 1977-81. N Engl J Med 1988; 312:265

    Article  Google Scholar 

  108. Plante S, Laarman G, de Feyter PJ, et al. Acute complications of percutaneous transluminal coronary angioplasty for totally occluded coronary arteries. Am Heart J 1991:121:417–426

    Article  PubMed  CAS  Google Scholar 

  109. Holmes DR Jr., Vlietstra RE, Reader GS, et al. Angioplasty in total coronary artery occlusions. J Am Coll Cardiol 1984; 3:845–9

    Article  PubMed  Google Scholar 

  110. Bell MR, Berger QB, Bresnahan JF, Reeder GS, Bailey KR, Holmes DR. Initial and long-term outcome of 354 patients after coronary balloon angioplasty of total coronary artery occlusions. Circulation 1992; 85:1003–11

    Article  PubMed  CAS  Google Scholar 

  111. DiSciasco G, Vetrovec GW, Cowley MJ, Wolfgang TC. Early and late outcome of PTCA for subacute and chronic coronary occlusion. Am Heart J 1986; 111:833–839

    Article  Google Scholar 

  112. Serruys PW, Umans V, Heyndrickx GR, et al. Elective PTCA of totally occluded arteries not associated with acute myocardial infarction; short-term and long-term results. Eur Heart J 1985; 6:2–12

    PubMed  CAS  Google Scholar 

  113. Melchior JP, Meier B, Urban P, et al. PTCA for chronic total coronary arterial occlusion. Am J Cardiol 1987; 59:536–8

    Article  Google Scholar 

  114. Lange RA, Cigarroa RG, Hillis LD. Influence of residual antegrade coronary blood flow on survival after myocardial infarction in patients with multivessel coronary artery disease. Coronary Artery Dis 1990; 1:59–63

    Article  Google Scholar 

  115. Ellis SG, Shaw RE, Gershony G, et al. Risk factors, time course and treatment effect for restenosis after successful percutaneous transluminal coronary angioplasty of chronic total occlusion. Am J Cardiol 1989; 63:897–901

    Article  PubMed  CAS  Google Scholar 

  116. Foley DP, Deckers J, van den Bos AA, Heyndrickx GR, Laarman GJ, Suryapranata H, Zijlstra F, Serruys PW. Usefulness of repeat coronary angiography 24 hours after successful balloon angioplasty to evaluate early luminal deterioration and facilitate quantitative analysis. Am J Cardiol 1993; 72:1341–1347

    Article  PubMed  CAS  Google Scholar 

  117. Hanet C, Wijns W, Michel X, Schroeder E. Influence of balloon size and stenosis morphology on immediate and delayed elastic recoil after percutaneous transluminal coronary angioplasty. J Am Coll Cardiol 1991; 18:506–511

    Article  PubMed  CAS  Google Scholar 

  118. Buller C, et al. Early recoil, dissection and reocclusion following PTCA of total coronary occlusions. Can J Cardiol 1994; 10[suppl]:276A (abstract)

    Google Scholar 

  119. Puma JA, Sketch MH Jr, Tcheng JE, Harrington RA, Phillips HR, Stack RS, Califf RM. Percutaneous revascularization of chronic coronary occlusions: An overview. J Am Coll Cardiol 1995; 26:1–11

    Article  PubMed  CAS  Google Scholar 

  120. Serruys PW, Leon M, Hamburger JN, et al. Recanalization of chronic total coronary occlusions using a laser guide wire: The Eu and US total experience. J Am Coll Cardiol 1996; 27[suppl A]: 152A

    Article  Google Scholar 

  121. Holmes DR Jr, Forrester JS, Utvack F, et al. Chronic total obstruction and short term outcome: The excimer laser coronary angioplasty registry experience. Mayo Clinic Prod 1993; 68:5–10

    Article  Google Scholar 

  122. Warth D, Cowley M. Percutaneous transluminal coronary rotational ablation of total coronary occlusions. Circulation 1992; 86 Suppl 1:1–781 (abstract)

    Article  Google Scholar 

  123. Hinohara T, Rowe MH, Roberstono GC, et al. Effect of lesion characteristics on outcome of directional coronary atherectomy. J Am Coll Cardiol 1991; 17:1112–20

    Article  PubMed  CAS  Google Scholar 

  124. Goldberg SL, Colombo A, Maiello L, Borrione M, Find L, Almagor Y. Intracoronary stent insertion after balloon angioplasty of chronic total occlusions. J Am Coll Cardiol 1995; 26:713–719

    Article  PubMed  CAS  Google Scholar 

  125. Medina A, et al. Effectiveness of coronary stenting for the treatment of chronic total occlusions in angina pectoris. Am J Cardiol 1994; 73:1222

    Article  PubMed  CAS  Google Scholar 

  126. Dorros G, Cowley MJ, Simpson J, et al. Percutaneous transluminal coronary angioplasty: report of complications from the National Heart, Lung, and Blood Institute PTCA Registry. Circulation 1983; 67:4723–730

    Article  Google Scholar 

  127. Hermans WRM, Rensing BJ, Foley DP, Deckers JW, Rutsch W, Emanuelsson H, Danchin N, Wijns W, Chappuis F, Serruys PW. “Therapeutic dissection” and the occurrence of restenosis. A quantitative angiographic analysis in 778 lesions after successful angioplasty. J Am Coll Cardiol 1992; 20:767–80

    Article  PubMed  CAS  Google Scholar 

  128. Rupprect HJ, Brennecke R, Bemhard G, Erbel R, Pop T, Meyer J. Analysis of risk factors for restenosis after PTCA. Cathet Cardiovasc Diagn 1990; 19:151–159

    Article  Google Scholar 

  129. Smith SH, Geer JC. Morphology of saphenous vein coronary artery bypass grafts. Arch Pathol Lab Med 1983; 107:13–18

    PubMed  CAS  Google Scholar 

  130. Cox JL, Chiasson DA, Gotlieb AV. Stranger in a strange land: the pathogenesis of saphenous vein graft stenosis with emphasis on structural and functional differences between veins and arteries. Prog Cardiovasc Dis 1991; 34; 45–68

    Article  PubMed  CAS  Google Scholar 

  131. Holmes DR JR, Topol EJ, Califf RM, et al. A multicenter, randomized trial of coronary angioplasty versus directional atherectomy for patients with saphenous vein bypass graft lesions. Circulation 1995; 91:1966–1974

    Article  PubMed  Google Scholar 

  132. Safian RD, Grines CL, May MA, Uchtenberg A, Juran N, Schreiber TL, Pavlides G, Meany TB, Savas V, O’Neill WW. Clinical and angiographic results of transluminal extraction coronary atherectomy in saphenous vein bypass grafts. Circulation 1994; 89:302–312

    Article  PubMed  CAS  Google Scholar 

  133. de Feyter PJ, van Suylen R-J, de Jaegere PPT, Topol EJ, Serruys PW. Balloon angioplasty for the treatment of lesions in saphenous vein bypass grafts. J Am Coll Cardiol 1993; 21:1539–49

    Article  PubMed  Google Scholar 

  134. Platko WP, Hollman J, Whitlow PL, Franco I. Percutaneous transluminal angioplasty of saphenous vein graft stenosis: long term follow-up. J Am Coll Cardiol 1989; 14:1645–50

    Article  PubMed  CAS  Google Scholar 

  135. Douglas JS, Gruentzig AR, King SB III, Hollman J, Ischinger T, Meier B, Craver JM, Jones EL, Waller EL, Bones DK, Guyton R. Percutaneous transluminal angioplasty in patients with prior coronary artery bypass surgery. J Am Coll Cardiol 1983; 2:745–754

    Article  PubMed  Google Scholar 

  136. Corbelli J, Franco I, Hollman J, Simpfendorfer C, Galan K. Percutaneous transluminal coronary angioplasty after previous coronary artery bypass surgery. Am J Cardiol 1985; 56:398–403

    Article  PubMed  CAS  Google Scholar 

  137. Reeder GS, Bresnahan JF, Holmes DR, Mock MB, Orszulak TA, Smith HC, Vlietstra RE. Angioplasty for aortocoronary bypass graft stenosis. Mayo Clin Proc 1986; 61:14–19

    Article  PubMed  CAS  Google Scholar 

  138. Meester BH, Samson M, Suryapranata H, et al. Long-term follow-up after attempted angioplasty of saphenous vein grafts: the Thoraxcenter experience 1981-1983. Eur Heart J 1991; 12:648–53

    PubMed  CAS  Google Scholar 

  139. Webb JG, Myler RK, Shaw RE, et al. Coronary angioplasty after coronary bypass surgery: initial results and late utcome in 422 patients. J Am Coll Cardiol 1990; 16:812–20

    Article  PubMed  CAS  Google Scholar 

  140. Plotter HWT, Meester BH, Serruys PW. The Dutch experience in percutaneous transluminal angioplasty of narrowed saphenous veins used for aortocoronary arterial bypass. Am J Cardiol 1991; 67:361–6

    Article  Google Scholar 

  141. Bittl JA, Sanbom TA, Yardley DE, Tcheng JE, Isner JM, Chokshi SK, Strauss BH, Abela GS, Schmidhofer M, Power JA. Percutaneous excimer laser coronary angioplasty of saphenous vein bypass graft lesions: Predictors of outcome. Am J Cardiol 1994; 74:144–148

    Article  PubMed  CAS  Google Scholar 

  142. Eeckhout E, Kappenberger L, Goy JJ. Stents for intracoronary placement: current status and future directions. J Am Coll Cardiol. 1996:27:757–765

    Article  PubMed  CAS  Google Scholar 

  143. Piana RN, Moscucci M, Cohen DJ, Kugelmass AK, Senerchia C, Kuntz RE, Baim DS. Palmaz-Schatz stenting for treatment of focal venin graft stenosis: immediate results and long-term outcome. J Am Coll Cardiol 1994; 23:1296–304

    Article  PubMed  CAS  Google Scholar 

  144. Wong SC, Bairn DS, Schatz RA, Teirstein PS, King SB, Curry JR RC, Heuser RR, Ellis SG, Cleman MW, Overlie P, Hirshfeld JW, Walker CM, Utvack F, Fish D, Brinker JA, Buchbinder M, Goldberg S, Chuang YC, Leon MB. Immediate results and late outcomes after stent implantation in saphenous vein graft lesions: the multicenter US Palmaz-Schatz stent experience. J Am Coll Cardiol 1995; 26:704–12

    Article  PubMed  CAS  Google Scholar 

  145. Savage M, Douglas J, Fischman D et al. Coronary stents versus balloon angioplasty for aorta-coronary saphenous vein bypass graft disease: interim results of a randomized trial. JACC. 1995:25:79A (abstract)

    Google Scholar 

  146. van der Zwet PMJ, Reiber JHC. A new approach for the quantification of complex lesion morphology: The gradient field transform (GFT): Basic principles and validation results. J Am Coll Cardiol 1994:24:216–224

    Article  PubMed  Google Scholar 

  147. Keane D, Gronenschild E, Slager C, Ozaki Y, Haase J, Serruys PW. In-vivo validation of an experimental adeaptive quantitative coronary angiography algorithm to circumvent overestimation of small luminal diameters. Cathet Cardiovasc Diagn 1995:36:17–24

    Article  PubMed  CAS  Google Scholar 

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Strauss, B.H., Natarajan, M.K. (1997). Lesion Morphology and Composition: Risk of Restenosis Following Coronary Interventions. In: Klein, L.W. (eds) Coronary Stenosis Morphology: Analysis and Implication. Developments in Cardiovascular Medicine, vol 190. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6287-0_13

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