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Radiation-induced bone and soft tissue sarcomas: Clinical aspects and molecular biology

  • Chapter
Soft Tissue Sarcomas: Present Achievements and Future Prospects

Part of the book series: Cancer Treatment and Research ((CTAR,volume 91))

Abstract

The development of treatment-induced cancer is one of the most devastating late complications of cancer therapy. Fortunately, these are quite uncommon in adult patients, that is, less than 1 in 200 at 20 years. In pediatric patients the risks are higher and may approach 1 in 5 at 20 years for patients with Ewing’s sarcoma and retinoblastoma.

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Authors
  1. Ira J. Spiro
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  2. Herman D. Suit
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Editors and Affiliations

  1. Department of Medical Oncology, Rotterdam Cancer Institute, Rotterdam, The Netherlands

    J. Verweij

  2. Department of Medical Oncology, Free University Hospital, Amsterdam, The Netherlands

    H. M. Pinedo

  3. Department of Radiation Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

    H. D. Suit

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Spiro, I.J., Suit, H.D. (1997). Radiation-induced bone and soft tissue sarcomas: Clinical aspects and molecular biology. In: Verweij, J., Pinedo, H.M., Suit, H.D. (eds) Soft Tissue Sarcomas: Present Achievements and Future Prospects. Cancer Treatment and Research, vol 91. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6121-7_10

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  • DOI: https://doi.org/10.1007/978-1-4615-6121-7_10

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